Clin Path LOs for Exam 2.docx

VM 7589 Clinical Pathology Learning Objectives for Exam 2 **[Transfusion Medicine]** 1. [Canine blood groups -- DEA = dog erythrocyte antigen] - - [Feline blood types] - - - - [Horse] - 2. \[see slides\] Know there are a lot! 3. *Neonatal Isoerythrolysis* - -...

VM 7589 Clinical Pathology Learning Objectives for Exam 2 **[Transfusion Medicine]** 1. [Canine blood groups -- DEA = dog erythrocyte antigen] - - [Feline blood types] - - - - [Horse] - 2. \[see slides\] Know there are a lot! 3. *Neonatal Isoerythrolysis* - - - - 4. **Hemolytic assay** → looks for hemolysis as an endpoint **Agglutinating assay** → loos for agglutination as an endpoint 5. Crossmatching: identifying serologic incompatibility between the donor and the recipient Why blood type and crossmatch? - - - Major crossmatch: donor RBC (antigen) + recipient plasma/serum (antibody) Minor crossmatch: donor plasma/serum (antibody) + recipient RBC (antigen) - A *compatible* crossmatch indicates that antibodies against red blood cells cannot be *detected*. 6. [Hemolytic transfusion reaction?] - - - - -