Clinical Pathology Learning Objectives for Exam 2 PDF

Summary

This document is a set of learning objectives for an exam in clinical pathology, focusing on transfusion medicine. It covers topics like canine blood groups, feline blood types, neonatal isoerythrolysis, hemolytic assays, agglutinating assays, crossmatching, and hemolytic transfusion reactions.

Full Transcript

VM 7589 Clinical Pathology Learning Objectives for Exam 2 **[Transfusion Medicine]** 1. [Canine blood groups -- DEA = dog erythrocyte antigen] - - [Feline blood types] - - - - [Horse] - 2. \[see slides\] Know there are a lot! 3. *Neonatal Isoerythrolysis* - -...

VM 7589 Clinical Pathology Learning Objectives for Exam 2 **[Transfusion Medicine]** 1. [Canine blood groups -- DEA = dog erythrocyte antigen] - - [Feline blood types] - - - - [Horse] - 2. \[see slides\] Know there are a lot! 3. *Neonatal Isoerythrolysis* - - - - 4. **Hemolytic assay** → looks for hemolysis as an endpoint **Agglutinating assay** → loos for agglutination as an endpoint 5. Crossmatching: identifying serologic incompatibility between the donor and the recipient Why blood type and crossmatch? - - - Major crossmatch: donor RBC (antigen) + recipient plasma/serum (antibody) Minor crossmatch: donor plasma/serum (antibody) + recipient RBC (antigen) - A *compatible* crossmatch indicates that antibodies against red blood cells cannot be *detected*. 6. [Hemolytic transfusion reaction?] - - - - -

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