Chapter 10 Cell Division and Mitosis PDF
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This document contains multiple choice questions about cell division, mitosis and the packaging of DNA into chromosomes. It includes questions about the separation of duplicated chromosomes, the replication of DNA prior to mitosis, and the structure and function of chromatin and histones.
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**Multiple Choice** +-----------------------------------------------------------------------+ | 1. The separation of duplicated chromosomes into two new nuclei is | | known as \_\_\_\_. | |...
**Multiple Choice** +-----------------------------------------------------------------------+ | 1. The separation of duplicated chromosomes into two new nuclei is | | known as \_\_\_\_. | | | | --- ----- ----------------- | | a. mitosis | | b. cytokinesis | | c. binary fission | | d. meiosis | | e. fertilization | | --- ----- ----------------- | | | | -------------------------- ---------------------------------------- | | ---------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.1 - Explain the three | | interrelated systems of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ---------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 2. A somatic cell divides to form two genetically identical daughter | | cells during mitosis. Prior to mitosis, what must occur? | | | | --- ----- ------------------------------------------ | | a. The cell must replicate its DNA. | | b. The cell must first be fertilized. | | c. The nucleus must divide. | | d. Chromatids must be separated. | | e. The nuclear envelope must disintegrate. | | --- ----- ------------------------------------------ | | | | -------------------------- ---------------------------------------- | | ---------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.1 - Explain the three | | interrelated systems of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | ---------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 3. At the conclusion of mitosis, each daughter cell has \_\_\_\_. | | | | --- ----- --------------------------------------------------------- | | ----------- | | a. twice the amount of DNA and half the cytoplasm of the par | | ent cell | | b. DNA identical to the parent cell | | c. half the DNA and half the cytoplasm found in the parent | | cell | | d. twice the cytoplasm and the same amount of DNA as the pa | | rent cell | | e. DNA genetically different from the parent cell | | --- ----- --------------------------------------------------------- | | ----------- | | | | -------------------------- ---------------------------------------- | | ---------------------------------- | | *ANSWER: * b | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.1 - Explain the three | | interrelated systems of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | ---------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 4. If a diploid cell with 40 chromosomes undergoes meiosis, each | | daughter nuclei will have \_\_\_\_ chromosomes. | | | | --- ----- ----- | | a. 10 | | b. 20 | | c. 40 | | d. 60 | | e. 80 | | --- ----- ----- | | | | -------------------------- ---------------------------------------- | | ----------------- | | *ANSWER: * b | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.2 - Compare mitosis an | | d meiosis. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | ----------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 5. Loosely packed regions of DNA associated with histones are called | | \_\_\_\_. | | | | --- ----- ------------------------- | | a. euchromatin | | b. heterochromatin | | c. chromosomes | | d. nucleosomes | | e. 30-nm chromatin fibers | | --- ----- ------------------------- | | | | -------------------------- ---------------------------------------- | | -------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.3 - Illustrate how DNA | | is packaged into chromosomes. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 6. The tight packing of chromatin into the chromosomes visible | | during nuclear division is possible due to links between \_\_\_\_ | | proteins. | | | | --- ----- ------------- | | a. Cdk | | b. H1 histone | | c. H3 histone | | d. H4 histone | | e. nonhistone | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------------------- | | *ANSWER: * b | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.3 - Illustrate how DNA | | is packaged into chromosomes. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 7. What is the role of nonhistone proteins in the nucleus? | | | | --- ----- ------------------------------------------------- | | a. to regulate nuclear envelope formation | | b. to facilitate nuclear transportation | | c. to provide additional chromosomal structure | | d. to disassemble the nuclear envelope | | e. to aid in microtubule formation during mitosis | | --- ----- ------------------------------------------------- | | | | -------------------------- ---------------------------------------- | | -------------------------------- | | *ANSWER: * c | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.3 - Illustrate how DNA | | is packaged into chromosomes. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 8. A plant cell with three sets of chromosomes is \_\_\_\_. | | | | --- ----- ------------- | | a. haploid | | b. diploid | | c. triploid | | d. tetraploid | | e. hexaploid | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------------------------------- | | *ANSWER: * c | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.4 - Describe the parti | | tioning process of chromosomes by mitosis. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | -------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 9. How many unique chromosomes does an organism with a chromosome | | number of 4*n*=32 have? Assume that none of these are sex | | chromosomes, and do not count any duplicate homologous chromosomes in | | this number. | | | | --- ----- ----- | | a. 4 | | b. 8 | | c. 16 | | d. 32 | | e. 64 | | --- ----- ----- | | | | -------------------------- ---------------------------------------- | | -------------------------------------------- | | *ANSWER: * b | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.4 - Describe the parti | | tioning process of chromosomes by mitosis. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | -------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 10. The \_\_\_\_ genome was the first eukaryotic genome to be | | sequenced. | | | | --- ----- ------------------------------ | | a. *Escherichia coli* | | b. *Caenorhabditis elegans* | | c. *Drosophila melanogaster* | | d. *Saccharomyces cerevisiae* | | e. *Schizosaccharomyces pombe* | | --- ----- ------------------------------ | | | | -------------------------- ---------------------------------------- | | ---------------------------------- | | *ANSWER: * d | | *REFERENCES: * 10.1 The Cycle of Cell Growth and Divisi | | on: An Overview | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.1.1 - Explain the three | | interrelated systems of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ---------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 11. At the conclusion of S phase, a diploid cell with 40 chromosomes | | will have \_\_\_\_ chromosomes and \_\_\_\_\_ sister chromatids. | | | | --- ----- --------- | | a. 20; 40 | | b. 20; 20 | | c. 40; 40 | | d. 40; 80 | | e. 80; 80 | | --- ----- --------- | | | | -------------------------- ---------------------------------------- | | ------------------ | | *ANSWER: * d | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.1 - Illustrate chromos | | ome segregation. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | ------------------ | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 12. If a cell has 36 chromosomes at the beginning of G~1~, how many | | chromosomes will be present at the end of G~2~? | | | | --- ----- ----- | | a. 36 | | b. 18 | | c. 72 | | d. 64 | | e. 44 | | --- ----- ----- | | | | -------------------------- ---------------------------------------- | | ------------------ | | *ANSWER: * a | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.1 - Illustrate chromos | | ome segregation. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | ------------------ | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 13. Early in mitosis, chromatin condenses. Which process takes place | | more easily as a result? | | | | --- ----- ------------------------------------------------------ | | a. disappearance of the nuclear envelope | | b. replication of DNA | | c. orderly distribution of DNA into the two new nuclei | | d. formation of the mitotic spindle | | e. disintegration of nucleoli | | --- ----- ------------------------------------------------------ | | | | -------------------------- ---------------------------------------- | | ------------------ | | *ANSWER: * c | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.1 - Illustrate chromos | | ome segregation. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | ------------------ | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 14. Compared to the parent cell, each of two daughter cells that | | result from normal mitotic division contains \_\_\_\_ chromosomes and | | is genetically \_\_\_\_. | | | | --- ----- ---------------------------------- | | a. the same number of; different | | b. the same number of; identical | | c. half the number of; different | | d. half the number of; identical | | e. double the number of; identical | | --- ----- ---------------------------------- | | | | -------------------------- ---------------------------------------- | | ------------------ | | *ANSWER: * b | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.1 - Illustrate chromos | | ome segregation. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | ------------------ | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 15. Where is the centromere found? | | | | --- ----- --------------------------------------------------------- | | -------------- | | a. position where metaphase chromosomes align | | b. location where the mitotic spindle forms | | c. central region of a chromosome where the spindle microtu | | bules attach | | d. location where chromosomes cluster during telophase | | e. center of the cell where the nucleus is found during pro | | phase | | --- ----- --------------------------------------------------------- | | -------------- | | | | -------------------------- ---------------------------------------- | | ------------------ | | *ANSWER: * c | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.1 - Illustrate chromos | | ome segregation. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ------------------ | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 16. If a cell contains 84 sister chromatids at metaphase of mitosis, | | how many chromosomes will be present in each nucleus in late | | telophase? | | | | --- ----- -------------------------------------------------- | | a. 168 | | b. 84 | | c. 42 | | d. 21 | | e. cannot be determined from the information given | | --- ----- -------------------------------------------------- | | | | -------------------------- ---------------------------------------- | | ------------------ | | *ANSWER: * c | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.1 - Illustrate chromos | | ome segregation. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | ------------------ | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 17. The cells produced by mitotic divisions are considered to be | | \_\_\_\_ the original cell. | | | | --- ----- -------------------------- | | a. smaller versions of | | b. genetically unique from | | c. clones of | | d. mutants of | | e. plasmids of | | --- ----- -------------------------- | | | | -------------------------- ---------------------------------------- | | ------------------ | | *ANSWER: * c | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.1 - Illustrate chromos | | ome segregation. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ------------------ | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 18. Replication of DNA occurs during \_\_\_\_. | | | | --- ----- -------------- | | a. S phase | | b. G~1~ phase | | c. G~0~ phase | | d. prophase | | e. cytokinesis | | --- ----- -------------- | | | | -------------------------- ---------------------------------------- | | -------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.2 - Describe the inter | | phase and its three subphases. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 19. Once human nerve cells become mature, they normally exit the cell | | cycle and remain in \_\_\_\_. | | | | --- ----- ----------- | | a. G~0~ | | b. G~1~ | | c. G~2~ | | d. S phase | | e. prophase | | --- ----- ----------- | | | | -------------------------- ---------------------------------------- | | -------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.2 - Describe the inter | | phase and its three subphases. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 20. Generally, which phase of the cell cycle varies the most in | | length? | | | | --- ----- --------------------------------------------- | | a. G~1~ | | b. S | | c. G~2~ | | d. M | | e. All phases are the same length among cells | | --- ----- --------------------------------------------- | | | | -------------------------- ---------------------------------------- | | -------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.2 - Describe the inter | | phase and its three subphases. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | -------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 21. Chromatin condenses into chromosomes and the mitotic spindle | | begins to form during \_\_\_\_. | | | | --- ----- ------------- | | a. interphase | | b. prophase | | c. metaphase | | d. anaphase | | e. telophase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * b | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 22. Chromosomes decondense into chromatin at which point in the cell | | cycle? | | | | --- ----- -------------------------------- | | a. at the beginning of S phase | | b. at the end of interphase | | c. at the beginning of prophase | | d. at the beginning of metaphase | | e. at the end of telophase | | --- ----- -------------------------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * e | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 23. Chromosomes are in a condensed form at which stage(s) of the cell | | cycle? | | | | --- ----- ------------------------------------------ | | a. prophase only | | b. prophase and metaphase | | c. interphase | | d. all stages of interphase and mitosis | | e. throughout mitosis until late telophase | | --- ----- ------------------------------------------ | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * e | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 24. Which sequence of the cell cycle is correct? | | | | --- ----- --------------------------------------------------------- | | ------------ | | a. prophase, metaphase, interphase, telophase, anaphase | | b. prometaphase, anaphase, prophase, telophase, interphase, | | metaphase | | c. anaphase, interphase, telophase, prometaphase, prophase, | | metaphase | | d. interphase, prophase, prometaphase, metaphase, anaphase, | | telophase | | e. interphase, metaphase, prometaphase, prophase, telophase | | , anaphase | | --- ----- --------------------------------------------------------- | | ------------ | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * d | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 25. During which phase(s) of mitosis are chromosomes composed of two | | sister chromatids? | | | | --- ----- ------------------------------------------------- | | a. prophase and prometaphase only | | b. prophase, prometaphase and metaphase | | c. prophase, prometaphase, metaphase and anaphase | | d. anaphase and telophase only | | e. all phases of mitosis | | --- ----- ------------------------------------------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * b | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | | | | | Answer the following questions using the accompanying figure. | | | | | | | | Figure 10.1 | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 26. Identify the stage of mitosis shown in panel A. | | | | --- ----- ------------- | | a. interphase | | b. prophase | | c. metaphase | | d. anaphase | | e. telophase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * a | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *PREFACE NAME: * Figure 10.1 | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 27. Identify the stage of mitosis shown in panel B. | | | | --- ----- ------------- | | a. interphase | | b. prophase | | c. metaphase | | d. anaphase | | e. telophase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * d | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *PREFACE NAME: * Figure 10.1 | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 28. Identify the stage of mitosis shown in panel C. | | | | --- ----- ------------- | | a. interphase | | b. prophase | | c. metaphase | | d. anaphase | | e. telophase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * b | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *PREFACE NAME: * Figure 10.1 | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 29. Identify the stage of mitosis shown in panel D. | | | | --- ----- ------------- | | a. interphase | | b. prophase | | c. metaphase | | d. anaphase | | e. telophase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * e | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *PREFACE NAME: * Figure 10.1 | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 30. Identify the stage of mitosis shown in panel E. | | | | --- ----- ------------- | | a. interphase | | b. prophase | | c. metaphase | | d. anaphase | | e. telophase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * c | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *PREFACE NAME: * Figure 10.1 | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 31. Karyotype analyses are performed on cells in \_\_\_\_ of | | mitosis. | | | | --- ----- --------------- | | a. prophase | | b. prometaphase | | c. metaphase | | d. anaphase | | e. telophase | | --- ----- --------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * c | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 32. Colchicine, a chemical extracted from the autumn crocus | | (C*olchicum autumnale*), inhibits the formation of microtubules. | | Mitotic cells exposed to colchicine will therefore be arrested at | | \_\_\_\_. | | | | --- ----- ------------- | | a. anaphase | | b. interphase | | c. prophase | | d. telophase | | e. metaphase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * e | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 33. During \_\_\_\_, microtubules disassemble, pulling the chromatids | | to the ends of the spindle. | | | | --- ----- ------------- | | a. prophase | | b. interphase | | c. anaphase | | d. metaphase | | e. telophase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * c | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 34. Embryonic development begins with a single egg fertilized by a | | single sperm, forming a zygote which then divides by mitosis. How | | many cells are present in the embryo at the conclusion of four | | mitotic divisions? | | | | --- ----- ----- | | a. 2 | | b. 4 | | c. 8 | | d. 16 | | e. 32 | | --- ----- ----- | | | | -------------------------- ---------------------------------------- | | ---------------------------- | | *ANSWER: * d | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.4 - Compare cytokinesi | | s between various species. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | ---------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 35. Cytokinesis typically begins during which stage of mitosis? | | | | --- ----- --------------- | | a. prophase | | b. prometaphase | | c. metaphase | | d. anaphase | | e. telophase | | --- ----- --------------- | | | | -------------------------- ---------------------------------------- | | -------------------- | | *ANSWER: * e | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.3 - Describe the five | | stages of mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | -------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 36. Which statement best describes the difference between cell | | division in plant and animal cells? | | | | --- ----- --------------------------------------------------------- | | --------------------------------------------------------------------- | | ----------------------- | | a. Cytokinesis occurs by formation of a cleavage furrow in | | animal cells, but not plant cells. | | b. Cytokinesis occurs by formation of a cleavage furrow in | | plant cells, but not animal cells. | | c. Centrosomes play an important role in spindle formation | | in plant cells, but not in animal cells. | | d. Chromosome replication occurs during interphase in anima | | l cells, while in plant cells, replication occurs when the nuclear en | | velope disintegrates. | | e. Animal cells divide via the cell cycle whereas plant cel | | ls divide by binary fission. | | --- ----- --------------------------------------------------------- | | --------------------------------------------------------------------- | | ----------------------- | | | | -------------------------- ---------------------------------------- | | ---------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.4 - Compare cytokinesi | | s between various species. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ---------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 37. Certain human cell types, such as skeletal muscle cells, have | | several nuclei per cell. Based on your understanding of mitosis, how | | could this happen? | | | | --- ----- --------------------------------------------------------- | | --------------------- | | a. The cell undergoes repeated cytokinesis but not mitosis. | | b. The cell undergoes repeated mitotic divisions with conco | | mitant cytokinesis. | | c. The cell undergoes repeated mitotic divisions but not cy | | tokinesis. | | d. The cell undergoes anaphase twice before entering teloph | | ase. | | e. The cell goes through multiple S phases before entering | | mitosis. | | --- ----- --------------------------------------------------------- | | --------------------- | | | | -------------------------- ---------------------------------------- | | ---------------------------- | | *ANSWER: * c | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.4 - Compare cytokinesi | | s between various species. | | *KEYWORDS: * Bloom's: Evaluate | | -------------------------- ---------------------------------------- | | ---------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 38. Organisms that reproduce asexually usually do so through the | | process of \_\_\_\_. | | | | --- ----- ------------------ | | a. mitosis | | b. meiosis | | c. gametogenesis | | d. spore formation | | e. fertilization | | --- ----- ------------------ | | | | -------------------------- ---------------------------------------- | | --------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.5 - Discuss the import | | ance of the mitotic cell cycle. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | --------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 39. When plants are produced by cloning, which process is most | | directly involved? | | | | --- ----- ------------------------ | | a. mitotic cell division | | b. binary fission | | c. meiotic cell division | | d. gamete production | | e. budding | | --- ----- ------------------------ | | | | -------------------------- ---------------------------------------- | | --------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.2 The Mitotic Cell Cycle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.2.5 - Discuss the import | | ance of the mitotic cell cycle. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | --------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 40. The mitotic spindle is primarily composed of \_\_\_\_. | | | | --- ----- ------------------------- | | a. actin | | b. intermediate filaments | | c. microtubules | | d. keratin | | e. motor proteins | | --- ----- ------------------------- | | | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | | *ANSWER: * c | | *REFERENCES: * 10.3 Formation and Action of the Mitotic | | Spindle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.3.1 - Explain the differ | | ent ways in which animals and plants form mitotic spindles. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 41. The microtubule organizing center (MTOC) of an animal cell is an | | identifiable structure known as the \_\_\_\_. | | | | --- ----- -------------- | | a. cell plate | | b. centrosome | | c. kinetochore | | d. centromere | | e. chromosome | | --- ----- -------------- | | | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | | *ANSWER: * b | | *REFERENCES: * 10.3 Formation and Action of the Mitotic | | Spindle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.3.1 - Explain the differ | | ent ways in which animals and plants form mitotic spindles. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 42. Centriole replication occurs during \_\_\_\_. | | | | --- ----- ------------- | | a. G~1~ phase | | b. S phase | | c. G~2~ phase | | d. prophase | | e. telophase | | --- ----- ------------- | | | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | | *ANSWER: * b | | *REFERENCES: * 10.3 Formation and Action of the Mitotic | | Spindle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.3.1 - Explain the differ | | ent ways in which animals and plants form mitotic spindles. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 43. Duplicated centrioles move to opposite poles of a(n) \_\_\_\_ | | cell during \_\_\_\_ of the cell cycle. | | | | --- ----- ---------------------------------------- | | a. animal; prophase | | b. plant; prophase | | c. animal; metaphase | | d. plant; metaphase | | e. both animal and plant cells; prophase | | --- ----- ---------------------------------------- | | | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.3 Formation and Action of the Mitotic | | Spindle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.3.1 - Explain the differ | | ent ways in which animals and plants form mitotic spindles. | | *KEYWORDS: * Bloom's: Understand | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 44. The microtubules making up the mitotic spindle attach to | | specialized structures called \_\_\_\_ that are found in the | | centromere region of the chromosome. | | | | --- ----- --------------- | | a. nucleosomes | | b. centrosomes | | c. kinetochores | | d. chromatids | | e. centrioles | | --- ----- --------------- | | | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | | *ANSWER: * c | | *REFERENCES: * 10.3 Formation and Action of the Mitotic | | Spindle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.3.1 - Explain the differ | | ent ways in which animals and plants form mitotic spindles. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 45. The microtubules of the mitotic spindle originate from the | | \_\_\_\_ in both plant and animal cells. | | | | --- ----- ----------------------------------------- | | a. microtubule organizing centers (MTOCs) | | b. centromere | | c. chromatid | | d. centriole | | e. centrosome | | --- ----- ----------------------------------------- | | | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | | *ANSWER: * a | | *REFERENCES: * 10.3 Formation and Action of the Mitotic | | Spindle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.3.1 - Explain the differ | | ent ways in which animals and plants form mitotic spindles. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 46. Research conducted by G.J. Gorbsky and colleagues suggests that | | during anaphase, chromosomes move as a consequence of \_\_\_\_. | | | | --- ----- ------------------------------------------------- | | a. a combined action of actin and microtubules | | b. the disassembly of kinetochore microtubules | | c. the movement of kinetochore microtubules | | d. constriction of the contractile protein actin | | e. sliding over or along kinetochore microtubules | | --- ----- ------------------------------------------------- | | | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | *ANSWER: * e | | *REFERENCES: * 10.3 Formation and Action of the Mitotic | | Spindle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.3.3 - Discuss the two me | | chanisms by which chromosomes move toward the poles during mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 47. In order to understand how chromosomes move during anaphase of | | mitosis, researchers tagged \_\_\_\_ with a fluorescent label before | | photobleaching the cell and examining chromosomal movement under a | | microscope. | | | | --- ----- ------------------------------ | | a. DNA | | b. kinetochore microtubules | | c. nonkinetochore microtubules | | d. histones | | e. motor proteins | | --- ----- ------------------------------ | | | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | *ANSWER: * b | | *REFERENCES: * 10.3 Formation and Action of the Mitotic | | Spindle | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.3.3 - Discuss the two me | | chanisms by which chromosomes move toward the poles during mitosis. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 48. In early experiments to understand the control of the cell cycle, | | researchers fused HeLa cells that were at different stages of the | | cell cycle. What did the results of these experiments suggest? | | | | --- ----- --------------------------------------------------------- | | -------------------------------------------------------- | | a. The concentrations of cyclin dependent kinases (Cdks) fl | | uctuate throughout the cell cycle. | | b. The concentrations of cyclins fluctuate throughout the c | | ell cycle. | | c. The cell cycle has three checkpoints through which the c | | ell must pass in order to progress through to mitosis. | | d. Microtubules play an essential role in the progression o | | f the cell cycle. | | e. Molecules in the cytoplasm control the progression of th | | e cell cycle. | | --- ----- --------------------------------------------------------- | | -------------------------------------------------------- | | | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ------------- | | *ANSWER: * e | | *REFERENCES: * 10.4 Cell Cycle Regulation | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.4.1 - Summarize the expe | | riments that led to the identification of molecules that control the | | cell cycle. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ------------- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 49. A cell is committed to progressing through the cell cycle through | | to mitosis once it transitions from \_\_\_\_. | | | | --- ----- --------------------------- | | a. G~2~ to prophase | | b. G~1~ to G~0~ | | c. G~1~ to S | | d. S to G~2~ | | e. telophase to cytokinesis | | --- ----- --------------------------- | | | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ---- | | *ANSWER: * c | | *REFERENCES: * 10.4 Cell Cycle Regulation | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.4.2 - Discuss the roles | | of the three internal checkpoints in the progression of the cell cycl | | e. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ---- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 50. Addition of mitosis-promoting factor (MPF) to germinal cells in | | the skin arrested in G~2~ leads the cells to \_\_\_\_. | | | | --- ----- -------------------------------------- | | a. stop dividing | | b. enter prophase | | c. undergo cytokinesis without mitosis | | d. die | | e. remain arrested in G~2~ | | --- ----- -------------------------------------- | | | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ---- | | *ANSWER: * b | | *REFERENCES: * 10.4 Cell Cycle Regulation | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.4.2 - Discuss the roles | | of the three internal checkpoints in the progression of the cell cycl | | e. | | *KEYWORDS: * Bloom's: Apply | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ---- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 51. One of the three internal cell cycle checkpoints occurs during | | \_\_\_\_ and monitors \_\_\_\_. | | | | --- ----- ---------------------------------------------------- | | a. the G~1~/S transition; mitotic spindle integrity | | b. late S phase; the presence of DNA damage | | c. the G~2~/M transition; the presence of DNA damage | | d. the G~2~/M transition; mitotic spindle integrity | | e. anaphase; the presence of DNA damage | | --- ----- ---------------------------------------------------- | | | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ---- | | *ANSWER: * c | | *REFERENCES: * 10.4 Cell Cycle Regulation | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.4.2 - Discuss the roles | | of the three internal checkpoints in the progression of the cell cycl | | e. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ---- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 52. During the mitotic spindle checkpoint, \_\_\_\_. | | | | --- ----- --------------------------------------------------------- | | ------------------ | | a. cells are in anaphase | | b. cells arrest if chromosomes are attached properly to the | | mitotic spindle | | c. cells become irreversibly committed to S phase | | d. proper spindle attachment to chromosomes is assessed | | e. cells enter G~0~ | | --- ----- --------------------------------------------------------- | | ------------------ | | | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ---- | | *ANSWER: * d | | *REFERENCES: * 10.4 Cell Cycle Regulation | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.4.2 - Discuss the roles | | of the three internal checkpoints in the progression of the cell cycl | | e. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | --------------------------------------------------------------------- | | ---- | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 53. What is the role of Cdks? | | | | --- ----- --------------------------------------------------------- | | --------- | | a. to add phosphate groups to target proteins | | b. to check for proper attachment of spindle fibers to chro | | mosomes | | c. to remove phosphate groups from cyclins | | d. to arrest the cell cycle | | e. to allow the cell cycle to work forward or backward | | --- ----- --------------------------------------------------------- | | --------- | | | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------------ | | *ANSWER: * a | | *REFERENCES: * 10.4 Cell Cycle Regulation | | *QUESTION TYPE: * Multiple Choice | | *LEARNING OBJECTIVES: * DYNS.RUSS.17.10.4.3 - Specify the role o | | f cyclins and cyclin-dependent kinases in cell cycle regulation. | | *KEYWORDS: * Bloom's: Remember | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------------ | +-----------------------------------------------------------------------+ +-----------------------------------------------------------------------+ | 54. If a dividing cell had no functional Cdk2 protein, the cell would | | not be able to \_\_\_\_. | | | | --- ----- --------------------------- | | a. phosphorylate cyclins | | b. transcribe the Cdk2 gene | | c. enter G~1~ | | d. translate cyclin mRNA | | e. degrade cyclins | | --- ----- --------------------------- | | | | -------------------------- ---------------------------------------- | | ------------------------------------------------------------------ | | *ANSWER: * c | | *REFERENCES: * 10.4 Cell Cycle Regulation | | *QUESTION TYPE: * Multiple Choice
