Clinical Chemistry 2 Lecture Notes PDF

TRACE AND TOXIC ELEMENTS ======================== **Essential element** - **Metalloenzyme** - **Metalloprotein** - **Dietary Requirement for Nutrients** - **Nonessential elements** - - **Trace Element** - **Ultratrace Element** - INSTRUMENTATION AND METHODS ----...

TRACE AND TOXIC ELEMENTS ======================== **Essential element** - **Metalloenzyme** - **Metalloprotein** - **Dietary Requirement for Nutrients** - **Nonessential elements** - - **Trace Element** - **Ultratrace Element** - INSTRUMENTATION AND METHODS --------------------------- **Atomic Absorption Spectrometer (AAS)** - **Emission Spectrum** - **Inductively Coupled Plasma Mass Spectrometry (ICP-MS)** - **Atomic Emission Spectroscopy** - **Atomic Absorption Spectroscopy** - SAMPLE COLLECTION AND PROCESSING -------------------------------- - - - - ATOMIC EMISSION SPECTROSCOPY ---------------------------- - 1. 2. 3. ATOMIC ABSORPTION SPECTROSCOPY ------------------------------ - - - 1. - a. b. 2. - 3. 4. INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY (ICP-MS) ----------------------------------------------------- - - 1. 2. 3. - - - - - ALUMINUM (Al) ------------- - - - ### SIGNS AND SYMPTOMS OF Al TOXICITY - - - - ### CLINICAL MANIFESTATIONS OF Al TOXICITY - - - ### LAB EVAL OF Al STATUS - - - - ARSENIC (As) ------------ - - ### SIGNS AND SYMPTOMS OF As TOXICITY - - - - - - - - - - ### ABSORPTION, TRANSPORT, AND EXCRETION - - - - - - - - - ### LAB EVAL OF As STATUS - - - CADMIUM (Cd) ------------ - - - ### ABSORPTION, TRANSPORT, AND EXCRETION - - - - - ### HEALTH EFFECTS AND Cd TOXICITY - - - ### LAB EVAL OF Cd STATUS - - - CHROMIUM (Cr) ------------- - - ### ABSORPTION, TRANSPORT, AND EXCRETION - - ### HEALTH EFFECTS, DEFICIENCY, AND Cr TOXICITY - - - - - - - - - - - ### LAB EVAL OF Cr STATUS - - - - COPPER (Cu) ----------- - - ### ABSORPTION, TRANSPORT, AND EXCRETION - ### HEALTH EFFECTS, DEFICIENCY, AND Cu TOXICITY - - - 1. 2. 3. 4. - - - - - - - - - - - ### LAB EVAL OF Cu STATUS - - -