Blood.pdf

Blood Marie A. Román Martínez, PhD Department of Biology Office hours: by appointment Email: [email protected] Copyright-This presentation is intended for educational purpose only. No part of this presentation may be reproduced or transmitted in any form without written permission. Objectives 1. D...

Blood Marie A. Román Martínez, PhD Department of Biology Office hours: by appointment Email: [email protected] Copyright-This presentation is intended for educational purpose only. No part of this presentation may be reproduced or transmitted in any form without written permission. Objectives 1. Describe the general characteristics and functions of blood. 2. Describe the appearance and healthy concentration of RBCs in blood. 3. Describe the structure of hemoglobin and its role. 4. Describe the process of hematopoiesis. 5. Explain how the RBCs are produced and destroyed. 6. Describe the structure and functions of each type of WBC. 7. Describe the production of WBCs. 8. Indicate the healthy concentration of WBCs in blood and the percentage of each type of WBC. 9. Describe the structure, production, and healthy concentration of platelets. 10. Describe the function of platelets. 11.Explain the CBC laboratory test. 12. Describe the sequence of events that occurs during hemostasis. 13. Explain the basis of blood typing and why it is important. 14. Identify the blood typing antigens and antibodies in each ABO blood type and Rh blood type. 15. Describe the major blood disorders. 2 General Characteristics of Blood Blood is a fluid connective tissue. Formed elements Formed elements the solid components, including blood cells and platelets suspended in plasma (matrix). It is heavier and more viscous than water. Blood pH: 7.35-7.45 Male blood volume: 5-6 Liters Female blood volume: 4-5 Liters Blood is approx. 8% of body weight Volume per body weight: 80-85 ml/kg Based on your body weight, estimate the volume in liters of your own blood? White Blood Cells (WBC) Red Blood Cells (RBC) 3 Blood composition If blood is centrifuged (spun at a very high speed) Blood fractionation 55% of blood volume consists of plasma. Liquid matrix of blood 45% of blood volume consists of formed elements hematocrit Most are red blood cells (RBCs)