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Campbell PA Program

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urologic imaging nephrological imaging medical imaging anatomy

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These notes provide a discussion on urologic and nephrological imaging techniques, covering topics like KUB, IVP, VCUG, RGP, renal ultrasound, CT scans, CT angiograms and MRIs. The notes cover indications, contraindications, and benefits for each technique.

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SKILLS Urologic and Nephrological Imaging 1. Discuss techniques, indications, contraindications, limitations, benefits, and risks of common uronephrological imaging studies including: KUB ○ In a KUB, the patient lies supine while 2-3 x-ray images are taken ○ KUB is indicated for abdominal pain in th...

SKILLS Urologic and Nephrological Imaging 1. Discuss techniques, indications, contraindications, limitations, benefits, and risks of common uronephrological imaging studies including: KUB ○ In a KUB, the patient lies supine while 2-3 x-ray images are taken ○ KUB is indicated for abdominal pain in the outpatient setting, kidney stones (mostly used in monitoring for stones), osseous abnormalities, and preliminary radiograph in series ○ Contraindications for the use of KUB is pregnancy ○ Patient does have to be able to hold breath for imaging in a KUB ○ The pros for a KUB is patient comfort, minimal radiation, and quick ○ The cons for a KUB is it provides a vague, non-specific imaging, and can produce poor imaging if the patient is constipated ○ KUB stands for kidney, ureters, and bladder Intravenous pyelography/urography (IVP) ○ In a IVP, patient will lies supine and be given IV contrast ○ A IVP requires bowel prep ○ A IVP is indicated for hematuria, recurrent UTI, flank pain and obstructive uropathy ○ A IVP is contraindicated in pregnancy, IV contrast allergy or iodine allergy, shellfish allergy, chronic kidney disease, Cr >2.0 ○ NOT commonly used since there are better imaging techniques Voiding cystourethrography (VCUG) ○ A VCUG requires the use of a urinary catheter to be able to push contrast media into the bladder. The imaging is then taken while voiding under fluoroscopy ○ A VCUG is indicated for young children with recurrent UTIs, or for monitoring post surgical corrections ○ A VCUG is contraindicated in pregnancy, shellfish allergy, iodine or contrast allergy ○ A VCUG is the only and best test for known vesicoureteral reflux ○ Cons for VCUG is possible UTI post-procedure Retrograde pyelography (RGP) ○ A RGP requires anesthesia ○ RGP is imaging of the ureters using contrast media directly into the ureters during fluoroscopy ○ Bowel prep is required for a RGP ○ You must educate your patients that a RGP procedure can cause mild hematuria, dysuria after procedure ○ A RGP is most commonly ordered in specialty urology care, not commonly used in primary care Renal ultrasound ○ A patient needs to arrive with a full bladder when getting a renal ultrasound and will void for a post-void residual imaging ○ A renal ultrasound can be dependant on body habitus and ultrasound technician ability ○ A renal ultrasound cannot evaluate ureters or surrounding anatomy ○ If a renal ultrasound is abnormal, the patient will need to be sent for a CT scan ○ A renal ultrasound is the test of choice for evaluation of renal failure ○ A renal ultrasound is the test of choice for unexplained acute kidney injury ○ A renal ultrasound is the test of choice for pregnant patients ○ A renal ultrasound is commonly used for children with suspected renal stones, renal cysts or palpable abdominal masses ○ A renal ultrasound is the screening test of choice for suspected PCKD ○ A renal ultrasound is the recommended initial modality for children and pregnant patients with microhematuria ○ A renal ultrasound can be used for evaluation of microhematuria Scrotal Ultrasound (not on objectives) ○ A scrotal ultrasound is indicated for for testicular pain, palpable mass, scrotal edema, scrotal trauma, and scrotal abscess ○ A scrotal ultrasound is the test of choice for testicular cancer and testicular torsion CT scan with or without contrast ○ A CT without contrast is indicated for possible kidney stones ○ A CT scan with or without contrast are contraindicated in pregnancy and in patients over 450 lbs ○ A CT with or without contrast should be cautiously used in children ○ A CT with IV contrast is indicated for patients with renal or adrenal masses, known malignancy staging, abdominal pain that is suspected appendicitis or diverticulitis, and trauma ○ CT of the abdomen with and without contrast is the preferred test for renal masses ○ Contraindications for a CT scan with contrast includes pregnancy, IV contrast allergy, chronic kidney disease or a CR > 1.9, or a prior history of CIN CT urogram ○ CT urogram is very similar to CT scans with/without contrast but has excellent specificity for renal, ureteral, bladder, and adrenal malignancy because the delayed phase will illuminate entire urinary tract and provide a 3D reconstruction ○ Indications for CT urogram are gross hematuria (meaning asymptomatic hematuria and smoker) and suspected pyelonephritis ○ Test of choice for microhematuria is the patient has asymptomatic microhematuria with a risk factors for a GU malignancy (such as smoking), but only if kidney function allows for the use of IV contrast CT Angiogram (not on objectives) ○ A CT angiogram is the best method for detecting renal artery stenosis and renal vein thrombus ○ CTA is the initial imaging study for renal artery stenosis ○ A CT angiogram should be performed in patients with unexplained progressive hypertension, since it could be renal artery stenosis MRI ○ A MRI should be cautioned for patients that are claustrophobic or unable to stay still ○ MRI cannot be used in patients with hardware and/or metal in the body ○ MRI is not commonly used in urology/nephrology, but can be used in a patient with chronic kidney disease with a suspicious renal or adrenal mass (with NO contrast) MR urogram ○ A MR urogram can be with or without contrast ○ A MR urogram is used to eliminate urinary system only and not the surrounding areas for evaluation ○ A MR urogram is okay to use in pediatric and pregnant patients ○ A MR urogram cannot reliably detect calculi 2. Nuclear medicine studies: Renal scintigraphy ○ A renal scintigraphy is only used for perfusion and function ○ A renal scintigraphy is the test of choice to determine obstructive versus nonobstructive hydronephrosis in children ○ This test detects obstructions by assessing images before and after administration of a diuretic ○ A renal scintigraphy is contraindicated in pregnant women or breastfeeding women Adrenal scintigraphy ○ NOT commonly used Captopril renogram ○ Captopril renogram helps determine if renovascular hypertension is present by comparing images before and after administration of Captopril (which is a ACE-inhibitor, given every 15 minutes for 1 hour) Renal angiography ○ In a renal angiography, dye is directly injected into the renal artery via a peripheral access in the groin to get a series of x-rays and fluoroscopy to watch for the dye to illuminate the renal artery ○ A renal angiography does require NPO for 6-8 hours before procedure, IV sedation, and leaving leg straight for 4-6 hours post procedure ○ Renal angiogram are indicated for confirmatory test following a CTA to look for renal artery stenosis ○ Renal angiography are contraindicated in pregnancy, therapeutic anticoagulation or antiplatelet therapy, bleeding disorders, IV contrast allergy, Chronic kidney disease, acute kidney injury or a Cr >1.9 ○ A con for renal angiogram is that CTA and MRA are better for initial tests 3. Counsel a patient on what to expect before, during, and after nephrourological imaging studies. 4. Compare and contrast “contrast induced nephropathy” and “nephrogenic systemic fibrosis” Contrast induced nephropathy ○ Contrast induced nephropathy is defined as “the impairment of kidney function after administration of IV contrast.” ○ Contrast induced nephropathy presents with a greater than 50% (or 0.5 increase) in creatinine from baseline that occurs within 48 to 72 hours post-procedure ○ Patients with chronic kidney disease or diabetes are at 4x greater risk for developing contrast induced nephropathy ○ If a patient is taking metformin, it must be stopped for 48 hours post contrast to prevent build up of the medication leading to lactic acidosis ○ A patient does not need any risk factors to have a contrast induced nephropathy ○ Symptoms include fatigue, peripheral edema, pruritus with lab changes of Cr increase >0.5 from baseline ○ Reversible Nephrogenic systemic fibrosis ○ Nephrogenic systemic fibrosis is defined as the thickening or tightening of the skin in large areas after exposure to gadolinium ○ Nephrogenic systemic fibrosis can occur within hours or years after exposure, but it typically occurs 2-10 weeks after exposure to gadolinium ○ There is no cure for nephrogenic systemic fibrosis and it will likely progressively worsen overtime ○ Symptoms include thick, tight skin, pruritus, papules with no lab changes

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