Biosafety Lecture (3)12 PDF

Biosafety BT (401) Prepared by Dr. Mohamed Hodhod Introduction to Biosafety and Risk Assessment “Guidelines and Regulations of Biosafety” Points preview Introduction. Guidelines in Biosafety. Regulations in Biosafety. Introducti Guideline Regulatio on...

Biosafety BT (401) Prepared by Dr. Mohamed Hodhod Introduction to Biosafety and Risk Assessment “Guidelines and Regulations of Biosafety” Points preview Introduction. Guidelines in Biosafety. Regulations in Biosafety. Introducti Guideline Regulatio on s ns Introduction Introducti Guideline Regulatio on s ns Introduction  Introducti Guideline Regulatio on s ns “There are several local, state, and federal agencies that either regulate or provide guidelines covering the use of biological agents”. Guidelines and Regulations  Introducti Guideline Regulatio on s ns Guidelines: “Biosafety guidelines are a set of practices and procedures necessary to be observed by personnel working in various facilities handling biological agents such as viruses, bacteria, fungi, parasites and GMOs”.  Introducti Guideline Regulatio on s ns Regulations: “Biosafety regulations are set of standards to be followed by personnel working in facilities handling biological agents. It is aimed to protect personnel from infections and also to avoid any harm to the community and the environment”.  Introducti Guideline Regulatio on s ns Glossary: CDC: “Centers for Disease Controls and Prevention”. NIH: “National Institutes of Health”. OSHA: “Occupational Safety and Health Administration”. USDA: “United States Department of Agriculture”. APHIS: “Animal and Plant Health Inspection Service”. Introducti Guideline Regulatio on s ns Introducti Guideline Regulatio on s ns Biosafety Guidelines  Introducti Guideline Regulatio on s ns Biosafety in Microbiological and Biomedical Laboratories (BMBL) Introducti Guideline Regulatio on s ns 2020 https://www.cdc.gov/labs/pdf/SF__19_308133-A_BMBL6_00-BOOK-WEB-final-3.pdf  Introducti Guideline Regulatio on s ns BMBL: “This document contains guidelines for microbiological safe work practices, procedures, safety equipment, and facilities that constitute the four established biosafety levels. Compliance with the BMBL is a requirement for work involving biological agents and toxins”.  Introducti Guideline Regulatio on s ns 2- Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines). Introducti Guideline Regulatio on s ns 2019 https://osp.od.nih.gov/wp-content/uploads/NIH_Guidelines.pdf  Introducti Guideline Regulatio on s ns NIH Guidelines: “This document provides guidelines for constructing and handling recombinant and synthetic nucleic acid molecules, and organisms containing such nucleic acid”. Introducti Guideline Regulatio on s ns Introducti Guideline Regulatio on s ns  Introducti Guideline Regulatio on s ns Biosafety Regulations  Introducti Guideline Regulatio on s ns 1- Occupational Safety and Health Administration (OSHA): Regulations for “Bloodborne Pathogens” Introducti Guideline Regulatio on s ns 2003 https://www.osha.gov/sites/default/files/publications/osha3186.pdf  Introducti Guideline Regulatio on s ns OSHA Regulations: “This document covers occupational exposure to human blood and other potentially infectious material, including human tissue and cells. OSHA specifies a combination of engineering controls, work practices, and training to reduce the risk of infection”.  Introducti Guideline Regulatio on s ns 2- Centers for Disease Controls and Prevention (CDC) and Animal and Plant Health Inspection Service (APHIS): Regulations for “Select Agent and Toxin Regulations”.  Introducti Guideline Regulatio on s ns 2021 https://www.selectagents.gov/compliance/guidance/training/docs/Regulation_Training_Requirements.pdf  Introducti Guideline Regulatio on s ns CDC and APHIS Regulations: “This document cover the possession, use, and transfer of biological agents and toxins that affect humans, animals, and plants and which have been determined to be potential bioterrorism agents. Entities and personnel who wish to work with select agents must be registered with the CDC or APHIS before acquiring or having access to select agents”. Thank you Any Question?!!!