BC-Exam 1-F24-Gift.pdf

Exam 1: A New Life The Gift N.B.: the questions may not appear in the order presented here as everything is randomized. The short answer question is not provided. An indicator of [REDACTED] means that 1 or more words, data, figures, etc., are not provided. Gerbil! Gerbil! Gerbil! Two structures...

Exam 1: A New Life The Gift N.B.: the questions may not appear in the order presented here as everything is randomized. The short answer question is not provided. An indicator of [REDACTED] means that 1 or more words, data, figures, etc., are not provided. Gerbil! Gerbil! Gerbil! Two structures are shown. Which one can exist? [REDACTED] Provide the single letter abbreviation for the shown amino acid: What is the overall charge of the shown peptide at pH 7? N-[REDACTED]-C Comparing a mutated form of a protein to a non-mutated form, the following sequence is determined to be the cause of the alpha-helix failure. What error(s) does the mutated form contain that can cause the helix to unwind? (Select all that apply) n-[REDACTED]-c Match the single letter abbreviation to the amino acid name Considering the side-chains of the amino acids, which other amino acid would have a titration curve similar to amino acid [REDACTED]? Determine if the statement provided is correct or incorrect. If the statement is incorrect, determine if clause (A), clause (B) or both possess errors. (A)The acidic proton of [REDACTED], (B) the proper name of [REDACTED]. Examining a mutated form of a protein to a non-mutated form, the following sequence is determined to be the cause of the alpha-helix failure. What error(s) does the mutated form contain that can cause the helix to unwind? (Select all that apply) n-[REDACTED]-c Provide the single letter abbreviation for the shown amino acid: The following sequence is from a section of an alpha helix. Given the sequence, to which amino acids is [REDACTED] hydrogen bonded? (Select all the apply) n-[REDACTED]-c From the given information determine the pH. (Use 2 decimal places) [REDACTED] Match the material with its correct classification: [REDACTED] Which covalent interaction is most likely to generate a bond with the greatest polarity? [REDACTED] Which of the solutions provided contains the greatest concentration of proton? pH [REDACTED] pH [REDACTED] pOH [REDACTED] pOH [REDACTED] For an acid HA, the concentration of HA and A- are [REDACTED]. What is [REDACTED]? (Use 2 decimal places) Which interaction is likely [REDACTED]? 1. Hydrogen bond in an ion rich environment. 2. Hydrogen bond in a hydrophobic environment. 3. Hydrogen bond in an aqueous environment. 4. Hydrogen bond in a low pH environment. An acid with a pKa of 7.07 is present in a solution with a pH of 7.69. [REDACTED]? (Use 2 decimal places) Below is shown the respiratory system and how the steady-state reactions interact with proton. An individual, unwillingly, shows a [REDACTED] rate. In terms of blood pH what could be happening? The [REDACTED] describes how [REDACTED] materials aggregate in aqueous solution. What is the driving force behind the [REDACTED] effect? What is a domain in reference to protein structure? Examining a mutated enzyme's alpha helix the following sequence is determined. The helix does not fold properly. What most likely explains this observation? n-[REDACTED]-c Match the structure with its descriptor. Examining a mutated enzyme's alpha helix the following sequence is determined. The helix does not fold properly. What most likely explains this observation? n-[REDACTED]-c Examining a mutated enzyme's alpha helix the following sequence is determined. The helix does not fold properly. What most likely explains this observation? n-[REDACTED]-c In the generation of [REDACTED] structure which of the following is true? Why does hemoglobin [REDACTED] binding affinity for oxygen as it moves through the blood to the [REDACTED]? (Select all that apply) What feature does a peptide bond possess that other [REDACTED] typically do not? (Select all that apply) Determine if the statement below is correct or incorrect. If the statement is incorrect determine if clause (A) or (B) or both contains the error. (A)[REDACTED] structure can be described as [REDACTED]; (B) [REDACTED] proteins with [REDACTED] structure do not have to possess [REDACTED] structures. For the following information determine the Vmax. (Enter a number only. Do not use units, do not use decimal places) [REDACTED] Which statement is one of the assumptions needed to use Michaelis-Menton Enzyme Kinetics analysis? Determine if the statement provided is correct or incorrect. If the statement is incorrect, determine if clause (A) or clause (B) or both possesses an error. (A)First order enzyme-reaction rates [REDACTED], (B) this asymptotic behavior of the velocity indicates [REDACTED]. If [S] = [REDACTED]Km, then what does the Vmax equal. Note: your answer will be some fraction of Vmax, not a specific number. Your answer should be in the form of X/YVmax When discussing first-order kinetics, using Michaelis Menton, what does the [REDACTED] reveal? For the following information determine the [REDACTED] of the enzyme system. [REDACTED] Vmax = [REDACTED] Km = [REDACTED] At [S] [REDACTED] For the following information determine the [REDACTED] of the enzyme system. (Use numbers only, not units. Do not use decimal places) Vmax = [REDACTED] Km = [REDACTED] At [S] [REDACTED] After dosing an enzyme-substrate system with an inhibitor, you note that the [REDACTED]-intercept of the Lineweaver Burke plot shifts from [REDACTED]. What is physically happening with the inhibitor and enzyme? What problem do [REDACTED] inhibitors encounter that reduces their effectiveness? For a Lineweaver Burke Graph, what does the [REDACTED] equal? Why is it frequently unfeasible to develop [REDACTED] inhibitors? Determine if the statement provided is correct or incorrect. If the statement is incorrect, determine if clause (A) or clause (B) or both possesses an error. (A)Transition-state inhibitors [REDACTED] target enzyme; (B) transition-state inhibitors [REDACTED] covalent bonds. Why can't Michaelis-Menton or Lineweaver-Burke approaches be used to analyze Transition state inhibitors and Suicide Inhibitors? For a Lineweaver Burke Graph, what does the [REDACTED] equal? After dosing an enzyme-substrate system with an inhibitor, you note that the [REDACTED] increases. What is physically happening with the inhibitor and enzyme? After dosing an enzyme-substrate system with an inhibitor, you see the following change in the graph. What is physically happening with the inhibitor and enzyme? (The black line is pre-treatment and the red line is post treatment). Consider the following Lineweaver-Burke equation. [REDACTED] What is the [REDACTED] of the system? (Enter a number only, do not use units, use up to 2 decimal places.) Warning potential gerbil question detected! Contact SCP! Short answer question, a kinetically active question to say the least!