Pharmacist A Exam Paper 2021 PDF

# फार्मेसिस्ट ए / PHARMACIST-A ## Instructions for Candidates: 1. You have been called for the written test based on the online data furnished by you in the web application. If you have wrongly entered in the web any information or you do not possess the required qualification as per our advertise...

# फार्मेसिस्ट ए / PHARMACIST-A ## Instructions for Candidates: 1. You have been called for the written test based on the online data furnished by you in the web application. If you have wrongly entered in the web any information or you do not possess the required qualification as per our advertisement, your candidature will be rejected. 2. The Question paper is in the form of Question Booklet with 80 questions and the duration of the test is 02 hours. 3. The questions will be objective type with four options out of which only one will be unambiguously correct. 4. Each question carries 04 marks and one mark will be deducted for each wrong answer. 5. A separate OMR answer sheet with carbon coated copy will be provided to mark the answer options. 6. You have to select the right answer by marking the corresponding oval on the OMR answer sheet by blue/black ball point pen. 7. Multiple answers for a question will be regarded as wrong answer. 8. Question booklet code printed on the top right corner should be written in the OMR answer sheet in the space provided. 9. Enter your Name and Roll Number correctly in the question booklet. 10. All entries in the OMR answer sheet should be with blue/black ball point pen only. 11. You should sign the hall ticket only in the presence of the Invigilator in the examination hall. 12. Computers, calculators, mobile phones and other electronic gadgets, text books, notes etc., will not be allowed inside the written test hall. 13. On completion of the thest, tear the OMR answer sheet along the perforation mark at the thep and hand over the original OMR answer sheet to the invigilator and retain the duplicate copy with you. 14. The question booklet can be retained by the candidates. 15. Candidates are not permitted to leave the examination hall during the first hour of the examination. ## Questions: 1. Saccharin is sweeter than sucrose by _ times. * 50 * 100 * 500 * 1000 2. How many millilitres of U-100 insulin should be used to obtain 40 units of insulin? * 40 * 4 * 0.4 * 400 3. In coffee seed, caffeine is present as a salt of _ . * Chlorogenic acid * Lysergic acid * Miconic acid * Uric acid 4. Prostaglandin analogues in ulcer therapy causes _ . * Diarrhoea * Abortion * Uterine bleeding * All of the above 5. Oral hypoglycemic agent which is a Thiazolidinedione derivative is _ . * Repaglinide * Glipizide * Pioglitazone * Glimepiride 6. BCG vaccine is _ . * Live attenuated viral vaccine * Live attenuated bacterial vaccine * Killed bacterial vaccine * Inactivated viral vaccine 7. The Central Drugs Research Institute is situated at _ . * Kolkata * Kasauli * Izzat Nagar * Lucknow 8. A receipt given by a seller to a buyer who has returned goods, which can be offset against future purchases is a _ . * Credit note * Invoice * Debit note * Bill 9. Which of the following is not a macrolide antibiotic? * Erythromycin * Spiramycin * Azithromycin * Vancomycin 10. Morphine is present in _ . * Atropa belladonna * Papaver somniferum * Ricinus communis * Solanum nigrum 11. Autoclaving of ampoules in a dye bath is for _ . * Clarity testing * Pyrogen testing * Leak testing * Sterility testing 12. Anticancer drugs kill cancer cells by _ . * Zero order kinetics * Pseudo first order kinetics * First order kinetics * Second order kinetics 13. Dopamine is degraded by _ . * MAO-A * MAO-B * Both (a) and (b) * None of the above 14. Tyndallization is the process of _ . * Sterilization by heating under pressure for 3 days * Sterilization by heating without pressure for 3 days * Sterilization by heating under pressure for 1 day * None of the above 15. Which of the following may cause cycloplegia when used topically in the eye? * Cortisone * Physostigmine * Pilocarpine * Atropine 16. Captopril exerts action by inhibiting conversion of _ . * Angiotensin I to II * Angiotensin II to I * Angiotensinogen to Angiotensin * Angiotensin to Angiotensinogen 17. The largest peak in a mass spectrum is called as _ . * Parent peak * Daughter peak * Metastable peak * Base peak 18. Keller Kiliani test is the identification test for _ . * Digitalis * Senna * Metformin * Rifampicin 19. The storage form of Iron in the human body is _ . * Ferritin * Ferrous fumarate * Heme * Globulin 20. Micromeritics refers to the study of _ . * Microscopes * Micro organisms * Metric system of measurement * Small particles 21. How many half lives is required to disintegrate 90% of a drug? * 3 * 4 * 1 * 2 22. A patient with Glucose 6 phosphate dehydrogenase deficiency if treated with Dapsone will develop _ . * Hemolytic anaemia * Pernicious anaemia * Diarrhoea * None of the above 23. Aztreonam is a _ . * Monobactum * Carbapenem * Betalactamase inhibitor * None of the above 24. DOTS refers to _ . * Divided Option Treatment System * Drug resistance Optimizing Treatment System * Directly Observed Treatment Short course * None of the above 25. Sublingually used organic nitrate is _ . * Nitroglycerine * Isosorbide dinitrate * Isosorbide mononitrate * Both (a) and (b) 26. Thromboxane is mainly synthesized by _ . * Lungs * Spleen * Platelets * Endothelium 27. The Wurster process can be used to _ . * Coat tablets * Determine the disintegration time * Gas sterilize parenteral solutions * Automatic filling of capsules 28. Emulsions containing more than two phases are called as _ . * Mixed emulsion * Heterogenous emulsion * Homogenized emulsion * Multiple emulsion 29. The hypotensive effect of Clonidine is due to action on _ . * Alpha adrenergic receptor * Beta adrenergic receptor * H1 receptor * H2 receptor 30. Antidiabetic agent of choice in diabetic ketoacidosis is _ . * Protamine Zinc Insulin * Isophane Insulin * Crystalline Insulin * Tolbutamide 31. Black pepper consists of the dried unripe fruits of _ . * Piper betle * Piper cubeba - * Piper longum * Piper nigrum 32. Reddish brown colour of calamine is due to _ . * Zinc chloride * Ferric chloride * Ferric oxide * Potassium permanganate 33. Disposable syringes are made of _ . * Polypropylene * Glass * Polytetrachloroethylene * None of the above 34. Which of the following is a physical sunscreen? * TiO2 * Para aminobenzoic acid * Methyl salicylate * Silicone oil 35. Seal coating is applied _ . * To build up the tablet size * To prevent moisture penetration into the tablet core * To round the edges * None of the above 36. Which vitamin contain steroidal structure? * Vitamin E * Vitamin A * Vitamin D * Vitamin C 37. Endothelium dependent relaxing factor of blood is _ . * Acetyl choline * Nor adrenaline * Nitric oxide * None of the above 38. 5HT3 antagonist used as anti-emetic agent is _ . * Ondansetron * Domperidone * Cisapride * Both (a) and (b) 39. All the following causes hyperglycemia except _ . * Streptozotocin * Diazoxide * Glucagon * Miglitol 40. The breakdown of glucose to pyruvic acid is called _ . * Glycolysis * Glucogenesis * Glycogenolysis * TCA cycle 41. Standard for Cosmetics is included in _ . * Schedule P * Schedule T * Schedule S * Schedule F 42. Poorly manufactured tablets may have small pinholes on the surface. This is called _ . * Mottling * Picking * Leaching * Cracking 43. The term bioavailability refers to the _ . * Relationship between the physical and chemical properties of a drug and its systemic absorption * Movement of the drug into body tissues over time * Dissolution of a drug in the gastrointestinal tract * Measurement of the rate and amount of therapeutically active drug that reaches systemic circulation 44. Selective inhibition of serotonin uptake is by _ . * Desipramine * Fluoxetine * Maprotoline * Lobeline 45. Largest organ in the body is _ . * Liver * Skin * Bone * Lungs 46. Which one is the unit of wave number? * Kaiser * Hertz * ms-¹ * cps 47. Capacity limited processes can be described by _ . * Linear kinetics * Nonlinear kinetics * Michaelis - Menten kinetics * Mixed kinetics 48. The cytotoxic drug with maximum emetic activity is _ . * Cisplatin * Chlorambucil * Methotrexate * Busulphan 49. Liver microsomal enzymes are stimulated by _ . * Cimetidine * Phenobarbitone * Procaine * Adrenaline 50. Which one of the following is an example of nonionic emulsifying agent? * Yellow paraffin wax * Bee's wax * Liquid paraffin * Spans 51. Rotoweigh is used to measure _ . * Rotation speed of capsules * Weight of capsules * Sorting speed of capsules * None of the above 52. Solid Fat Index (SFI) is determined by _ . * Potentiometry * Amperometric titration * Voltametry * Dilatometry 53. Ergotoxine contains _ . * Ergocryptine * Ergocristine * Ergocornine * All of the above 54. The particles which are deeply bonded, settle rapidly, easily redispersible are known as _ . * Coagules * Defloccules * Floccules * Sediments 55. Nux vomica seeds contain _ . * Unicellular lignified covering trichomes * Unicellular conical covering trichomes * Unicellular biseriate head * Multicellular unbranched trichomes 56. The active metabolite of Diazepam is _ . * Nitrazepam * Nor Diazepam * Des methyl fluorazepam * None of the above 57. NSAIDs produce ulcerogenic actions because _ . * They decrease acid secretion in stomach * They increase mucus secretion in stomach * They increase mucosal blood flow in stomach * None of the above 58. End product of Purine catabolism in man is _ . * Allantoin * Inosine * Uric acid * Xanthine 59. Asafoetida is obtained from _ . * Afghanistan * Spain * Burma * Malaysia 60. Liquid paraffin is of _ . * Animal origin * Mineral origin * Synthetic origin * Semisynthetic origin 61. The term MDT (Multi Drug Therapy) is related to _ . * Leprosy * Tuberculosis * Amoebiasis * Giardiasis 62. Dihydropyridine ring containing Calcium channel blocker is _ . * Verapamil * Diltiazem * Nifedipine * Losartan 63. To prevent INH induced neurotoxicity, _ is given along with it. * Pyridoxine * Niacin * Cyanocobalamine * Riboflavin 64. Endotoxin is produced by the following bacteria except _ . * Salmonella typhi * Bordetella pertussis * Yersinia pestis * Clostridium tetani 65. The drug Amikacin is derived from _ . * Kanamycin * Sisomicin * Gentamicin * Neomycin 66. The term Amplum denotes _ . * Tablespoonful * Teaspoonful * Dessertspoonful * Wineglassful 67. Bile is produced by _ . * Gallbladder * Liver * Pancreas * Intestine 68. Morphine does not cause _ . * Constriction of pupil * CNS depression * Respiratory depression * Diarrhoea 69. Barrier creams are used to protect the skin from _ . * Sunlight injury * Microorganisms * Viral infections * Industrial chemicals and UV rays 70. Epinephrine is added to local anaesthetics to _ . * Cause haemostasis * Prolong the action of the drug * Stimulate healing of wound * Decrease side effects 71. The phenomenon of repeated administration of a drug resulting in cell receptor blockage is known as _ . * Tachyphylaxis * Idiosynchrosy * Tolerance * Synergism 72. BAL is used against which metal poisoning? * Copper * Cyanide * Mercury * Iron 73. An oral hypoglycemic agent which is a Dipeptidyl peptidase-4 inhibitor is _ . * Pioglitazone * Sitagliptin * Liraglutide * Empagliflozin 74. A low volume of distribution of a drug indicates _ . * Short biological life * Does not accumulate in various organs * Not bioavailable * None of the above 75. The mineral deficient in milk is _ . * Phosphorous * Sodium * Potassium * Iron 76. Which of the following monoclonal antibody is fully human in origin? * Daclizumab * Infliximab * Adalimumab * Edrecolomab 77. Optic neuritis is a side effect of _ . * Sulphasalazine * Rifampicin * Ethambutol * Pyrazinamide 78. Which among the following is contra indicated in patients with eGFR less than 15mg/ml/1.75m²? * Insulin * Metformin * Linagliptin * None of the above 79. Precursor of Thyroxine, epinephrine and nor epinephrine is _ . * Phenyl alanine * Valine * Threonine * Tyrosine 80. The hardness range of tablets is usually _ . * 1-2 kg * 0.5-1 kg * 3-7 kg * None of the above