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Allosteric Modifiers (Inhibitors and Activators) PDF

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Document Details

SpeedyBarbizonSchool

Uploaded by SpeedyBarbizonSchool

Tanta University Faculty of Medicine

Tags

allosteric inhibitors enzymes biology molecular biology

Summary

This document explains allosteric inhibitors and activators. It describes how these small organic molecules can bind to enzymes outside of their active site to potentially decrease or increase activity. The document includes an example of ATP as an allosteric modifiers

Full Transcript

- Allosteric modifiers (inhibitors and activators) Allosteric inhibitors: They are usually small organic molecules that bind to a specific site away from the catalytic site and produce conformational changes in protein structure that lead to decreased activity of the enzyme Example : ATP for phospho...

- Allosteric modifiers (inhibitors and activators) Allosteric inhibitors: They are usually small organic molecules that bind to a specific site away from the catalytic site and produce conformational changes in protein structure that lead to decreased activity of the enzyme Example : ATP for phosphofructokinase-1 - Allosteric modifiers (inhibitors and activators) 1

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