Laboratory Safety Manual PDF

LABORATORY SAFETY MANUAL DECEMBER 2023 EDITION Environmental Health and Safety University of Washington Box 354400 Seattle, WA 98195-4400 Phone: 206.543.7262 FAX: 206.543.3351 www.ehs.washington.edu FORWARD The policies and procedures in this manual were developed by the University of Washington Environmental Health and Safety (EH&S) Department to provide information to protect workers and the surrounding environment and to achieve compliance with applicable standards and regulations. This manual is developed in coordination with the University of Washington’s Institutional Chemical and Physical Safety Committee (ICAPS) with the expectation that updates will be necessary as changes in regulations, policies and procedures dictate. Implementation of these policies and procedures is the responsibility of the Responsible Party (RP) or Principal Investigator (PI) and depends largely on the efforts of laboratory supervisors and employees. It is essential that they seek additional advice and training when needed to conduct research in a manner that is safe for University personnel, students, and the surrounding community. To assist in this endeavor, the services of the Environmental Health and Safety Department are available at the University of Washington. TABLE OF CONTENTS December 2023 ￜ Page 3 of 213 TABLE OF CONTENTS EMERGENCY INFORMATION............................................................................................................................................... 13 LABORATORY-SPECIFIC INFORMATION............................................................................................................................. 14 SECTION 1: LABORATORY RESPONSIBILITIES................................................................................................................... 17 A. PURPOSE................................................................................................................................................................. 18 1. Chemical Hygiene Plan (CHP)....................................................................................................................... 18 2. Regulations Pertaining to the Chemical Hygiene Plan.............................................................................. 18 3. Chemical Hygiene Plan Accessibility............................................................................................................ 19 4. Other Plans and References......................................................................................................................... 19 5. Applicability to Students............................................................................................................................... 19 B. SCOPE AND APPLICATION..................................................................................................................................... 19 1. Chemical Laboratory..................................................................................................................................... 20 2. Chemical and Non-Chemical Hazards......................................................................................................... 20 C. RESPONSIBILITIES................................................................................................................................................... 20 1. Responsible Party (RP) and Chemical Hygiene Officer (CHO).................................................................. 21 2. Dean, Department Chair and Director........................................................................................................ 25 3. Employees/Students...................................................................................................................................... 27 4. UW Chemical Hygiene Officer (CHO)........................................................................................................... 28 5. Institutional Chemical and Physical Safety Committee (ICAPS)............................................................... 28 SECTION 2 - CHEMICAL MANAGEMENT............................................................................................................................ 29 A. BASIC LABORATORY SAFETY PRACTICES............................................................................................................. 31 1. Working Alone................................................................................................................................................ 31 2. Prevent Chemical Exposure.......................................................................................................................... 31 3. Washing Hands.............................................................................................................................................. 32 4. Food and Drink............................................................................................................................................... 32 5. Access to Emergency Exits and Equipment................................................................................................ 32 6. Laboratory Signs............................................................................................................................................ 32 7. Housekeeping................................................................................................................................................. 33 8. Sharps Safety.................................................................................................................................................. 33 B. CHEMICAL INVENTORY AND THE SAFETY DATA SHEET (SDS)........................................................................... 34 1. Access to MyChem......................................................................................................................................... 34 2. Conducting Your Chemical Inventory......................................................................................................... 34 3. Safety Data Sheet (SDS)................................................................................................................................. 35 C. CHEMICAL PROCUREMENT................................................................................................................................... 35 1. Hazardous Chemicals.................................................................................................................................... 35 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS Page 4 of 213 ￜ December 2. 2023 Pharmaceuticals............................................................................................................................................. 36 3. DEA Controlled Substances.......................................................................................................................... 36 4. Non-Denatured Ethyl Alcohol....................................................................................................................... 36 5. Radioactive Materials.................................................................................................................................... 36 6. Highly Dangerous Materials......................................................................................................................... 36 7. Compressed Gas Cylinder Procurement.................................................................................................... 36 8. Chemical Exchange........................................................................................................................................ 37 9. Additional exceptions.................................................................................................................................... 37 D. CHEMICAL STORAGE.............................................................................................................................................. 37 1. Evaluate Chemical Hazards for Storage...................................................................................................... 37 2. Chemical Storage Practices.......................................................................................................................... 38 3. Chemical Storage Quantity Limits............................................................................................................... 42 E. CHEMICAL LABELING............................................................................................................................................. 42 1. Original Container.......................................................................................................................................... 42 2. Labeling Stock / Working Solutions............................................................................................................. 43 F. TRANSPORTING CHEMICALS................................................................................................................................. 44 1. Transporting between Floors and Buildings on Campus......................................................................... 45 2. Transporting Chemicals off Campus........................................................................................................... 46 3. Receiving Chemical Shipments.................................................................................................................... 46 G. SPECIAL CHEMICAL HAZARDS............................................................................................................................... 47 1. Highly Dangerous Chemicals........................................................................................................................ 47 2. Particularly Hazardous Substances............................................................................................................. 47 3. Reactive Chemicals........................................................................................................................................ 48 4. Potentially Explosive Chemicals................................................................................................................... 49 5. Highly Toxic Substances................................................................................................................................ 51 6. Carcinogens and Reproductive Hazards..................................................................................................... 52 7. Sensitizing or Allergenic Chemicals............................................................................................................. 54 8. Synthesized Chemicals.................................................................................................................................. 54 9. Compressed Gases, Gas Cylinders and Liquid Cryogen Containers....................................................... 55 10. Flammable and Combustible Liquids.......................................................................................................... 57 11. Homeland Security Chemicals of Interest.................................................................................................. 60 12. Process Safety for Highly Hazardous Chemicals....................................................................................... 60 13. Chemotherapy and Hazardous Drugs........................................................................................................ 60 H. REGULATED HAZARDOUS CHEMICALS LISTED UNDER THE WAC WASHINGTON VERTICAL STANDARD 61 SECTION 3: CHEMICAL WASTE MANAGEMENT................................................................................................................ 63 A. HAZARDOUS CHEMICAL WASTE RESPONSIBILITIES........................................................................................... 65 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS December 2023 ￜ Page 5 of 213 1. Laboratory Workers....................................................................................................................................... 65 2. UW EH&S Environmental Programs............................................................................................................ 65 B. WHAT QUALIFIES AS HAZARDOUS WASTE?......................................................................................................... 65 1. Flammable/Ignitable...................................................................................................................................... 65 2. Corrosive......................................................................................................................................................... 66 3. Reactive........................................................................................................................................................... 66 4. Toxic................................................................................................................................................................. 66 5. Carcinogenic................................................................................................................................................... 68 6. Waste Evaluation Request............................................................................................................................ 68 C. HAZARDOUS WASTE ACCUMULATION RULES.................................................................................................... 69 1. Appropriate Containers................................................................................................................................ 69 2. Hazardous Waste Labels............................................................................................................................... 69 3. Segregation..................................................................................................................................................... 70 4. Accumulation Limits...................................................................................................................................... 70 5. Large Containers (Drums)............................................................................................................................. 70 6. Inherently Waste-like Chemicals.................................................................................................................. 71 D. HAZARDOUS WASTE COLLECTION REQUESTS................................................................................................... 71 1. Hazardous Waste Collection Overview....................................................................................................... 71 2. Collection Requests – One-Time.................................................................................................................. 71 3. Routine Collection Requests......................................................................................................................... 71 4. Waste Cleanouts............................................................................................................................................ 71 5. What Happens to Hazardous Waste?.......................................................................................................... 72 E. TRASH DISPOSAL.................................................................................................................................................... 72 1. Trash Disposal of Chemicals......................................................................................................................... 72 2. Trash Disposal of Empty Chemical Containers.......................................................................................... 72 3. Trash Disposal of Contaminated Items....................................................................................................... 73 F. DISCHARGES TO THE SANITARY SEWER.............................................................................................................. 74 1. King County Local Sewer Discharge Limits................................................................................................. 74 2. Outside King County...................................................................................................................................... 74 3. Treating Hazardous Wastes.......................................................................................................................... 74 4. Soaps, Bleach and Acetone........................................................................................................................... 74 5. Scintillation Fluids.......................................................................................................................................... 75 6. Dilution Prohibition....................................................................................................................................... 75 G. CHEMICAL WASTES OF PARTICULAR CONCERN................................................................................................. 75 1. Unknown Chemicals...................................................................................................................................... 75 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS Page 6 of 213 ￜ December 2. 2023 Potentially Explosive Wastes........................................................................................................................ 75 3. Legacy Chemicals........................................................................................................................................... 76 H. HAZARDOUS WASTE MINIMIZATION................................................................................................................... 76 1. Treatment and Recycling in the Laboratory............................................................................................... 76 2. Hazardous Materials Recycling.................................................................................................................... 76 I. SOLID WASTE AND RECYCLING............................................................................................................................... 77 1. Paper and Cardboard.................................................................................................................................... 77 2. Plastic and Glass............................................................................................................................................. 77 3. Packaging Materials....................................................................................................................................... 77 4. Printer Cartridges........................................................................................................................................... 77 5. Batteries.......................................................................................................................................................... 77 6. Metallic Lead................................................................................................................................................... 78 J. SHARPS, LAB GLASS AND PLASTIC.......................................................................................................................... 78 1. Sharps.............................................................................................................................................................. 78 2. Trace Chemo/Hazardous Drugs Sharps.................................................................................................... 79 3. Biohazardous Glass and Plastic Items........................................................................................................ 79 4. Lab Glass......................................................................................................................................................... 79 K. INFECTIOUS OR BIOLOGICAL WASTE................................................................................................................... 80 L. RADIOACTIVE WASTE............................................................................................................................................. 80 M. MIXED WASTE.......................................................................................................................................................... 80 N. LIQUID SCINTILLATION COCKTAILS..................................................................................................................... 80 O. ANIMALS AND ANIMAL BY-PRODUCTS................................................................................................................ 80 1. Contaminated Animals and Animal By-Products...................................................................................... 80 2. Non-Contaminated Animals and Animal By-Products.............................................................................. 80 P. GAS CYLINDERS...................................................................................................................................................... 81 SECTION 4 - LABORATORY EQUIPMENT AND FACILITIES............................................................................................... 83 A. EMERGENCY EYEWASHES AND SHOWERS.......................................................................................................... 85 1. Eyewash Stations........................................................................................................................................... 85 2. Safety Showers............................................................................................................................................... 85 3. Deluge Hoses.................................................................................................................................................. 85 B. FIRE SAFETY EQUIPMENT...................................................................................................................................... 86 1. Fire Extinguisher............................................................................................................................................ 86 2. Flammable Storage Cabinets........................................................................................................................ 87 3. Flammable Storage Refrigerators................................................................................................................ 87 C. LABORATORY SIGNS.............................................................................................................................................. 88 1. Lab Caution Sign............................................................................................................................................ 88 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS December 2023 ￜ Page 7 of 213 2. Emergency Procedures for Laboratories.................................................................................................... 89 3. Laboratory Floor Plan.................................................................................................................................... 89 4. Emergency/Safety Equipment Location Signs............................................................................................ 90 5. Hazards Warning Signs................................................................................................................................. 90 6. Natural Gas Emergency Shut Off Valve....................................................................................................... 90 7. Laboratory Water – Do Not Drink................................................................................................................ 90 D. LABORATORY VENTILATION.................................................................................................................................. 90 1. Laboratory Design......................................................................................................................................... 90 2. Fume Hoods.................................................................................................................................................... 90 3. Perchloric Fume Hoods................................................................................................................................. 93 4. Glove Boxes.................................................................................................................................................... 93 5. Biological Safety Cabinets............................................................................................................................. 93 6. Laminar Flow Hoods...................................................................................................................................... 93 7. Ductless Laboratory Hoods.......................................................................................................................... 93 8. Cold Rooms, Warm Rooms and Environmental Chambers..................................................................... 94 9. Other Ventilation Systems............................................................................................................................ 95 10. Maintenance of Ventilation Systems........................................................................................................... 95 E. OTHER FACILITY CONDITIONS.............................................................................................................................. 96 1. General Laboratory Environment................................................................................................................ 96 2. Electrical Hazards........................................................................................................................................... 98 3. Lockout / Tagout Concerns......................................................................................................................... 100 4. Equipment Guards and Mounting............................................................................................................. 100 5. Confined Spaces........................................................................................................................................... 100 F. LABORATORY APPARATUS AND EQUIPMENT................................................................................................... 100 1. General Safety Work Practices................................................................................................................... 101 2. Refrigerators and Freezers......................................................................................................................... 102 3. Stirring and Mixing Equipment.................................................................................................................. 102 4. Heating Equipment...................................................................................................................................... 102 5. Ultrasonicators............................................................................................................................................. 107 6. Centrifuges.................................................................................................................................................... 107 7. Rotary Evaporators...................................................................................................................................... 107 8. Autoclaves..................................................................................................................................................... 107 9. Vacuum Systems.......................................................................................................................................... 107 10. Equipment maintenance............................................................................................................................. 108 G. DECONTAMINATION OF WORK AREAS.............................................................................................................. 109 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS Page 8 of 213 ￜ December 1. 2023 Custodial Services........................................................................................................................................ 109 2. Servicing of Lab Area or Equipment.......................................................................................................... 109 H. DECONTAMINATION OF EQUIPMENT FOR DISPOSAL..................................................................................... 109 1. Equipment Used to Process/Store Chemicals.......................................................................................... 111 2. Equipment Used to Process/Store Radionuclides................................................................................... 111 3. Equipment Used to Process/Store Biological Material........................................................................... 111 SECTION 5 - EMPLOYEE HEALTH AND PPE..................................................................................................................... 113 A. ENVIRONMENTAL MONITORING AND MEDICAL SURVEILLANCE.................................................................. 114 1. Exposure Limits............................................................................................................................................ 114 2. Special Chemical Air Monitoring................................................................................................................ 114 3. Possible Over-Exposure.............................................................................................................................. 115 4. Medical Evaluations..................................................................................................................................... 115 B. PERSONAL PROTECTIVE EQUIPMENT (PPE)...................................................................................................... 115 1. Eye Protection............................................................................................................................................... 117 2. Personal Apparel.......................................................................................................................................... 118 3. Gloves............................................................................................................................................................ 119 4. Respirators.................................................................................................................................................... 120 5. Hearing Protectors....................................................................................................................................... 121 6. PPE: Outside the Laboratory...................................................................................................................... 121 SECTION 6 - STANDARD OPERATING PROCEDURES..................................................................................................... 123 A. STANDARD OPERATING PROCEDURES (SOPS)................................................................................................. 124 B. SOP COMPONENTS.............................................................................................................................................. 124 1. Process Identification.................................................................................................................................. 124 2. Chemicals and Hazards............................................................................................................................... 124 3. Personal Protective Equipment (PPE)........................................................................................................ 124 4. Environmental/Ventilation Controls.......................................................................................................... 125 5. Special Handling Procedures & Storage Requirements......................................................................... 125 6. Spill and Accident Procedures.................................................................................................................... 125 7. Waste Disposal............................................................................................................................................. 125 8. Special Precautions for Animal Use........................................................................................................... 125 9. Approval Required....................................................................................................................................... 125 10. Decontamination......................................................................................................................................... 126 11. Designated Area........................................................................................................................................... 126 C. EXAMPLE SOPS..................................................................................................................................................... 126 D. STEPS TO DEVELOP YOUR SOPS......................................................................................................................... 126 1. Step 1 – Modify Existing SOPs.................................................................................................................... 126 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS December 2023 ￜ Page 9 of 213 2. Step 2 – Identify Requirements.................................................................................................................. 126 3. Step 3 – Complete the SOPs....................................................................................................................... 127 4. Step 4 – File the SOPs.................................................................................................................................. 127 5. SOP Training................................................................................................................................................. 127 6. Distributing Copies of the SOPs................................................................................................................. 127 7. Update SOPs as Needed............................................................................................................................. 127 SECTION 7 - SAFETY TRAINING......................................................................................................................................... 129 A. SAFETY TRAINING REQUIREMENTS.................................................................................................................... 130 B. EH&S SAFETY TRAINING RECORDS.................................................................................................................... 130 C. LABORATORY-SPECIFIC TRAINING AND RECORDS.......................................................................................... 130 1. Undergraduate students in the laboratory.............................................................................................. 131 D. UW OFFICE OF RESEARCH - RESEARCH REQUIRED TRAINING........................................................................ 131 SECTION 8 - RECORD KEEPING......................................................................................................................................... 133 A. CURRENT RECORDS MAINTAINED IN THE LABORATORY/DEPARTMENT...................................................... 134 1. Chemical Hygiene Plan................................................................................................................................ 134 2. Chemical Inventory...................................................................................................................................... 134 3. Safety Data Sheets (SDSs)........................................................................................................................... 134 4. Incident/Accident Reports.......................................................................................................................... 134 5. Safety Training Records............................................................................................................................... 134 6. Chemical Treatment Log............................................................................................................................. 134 7. Exposure Monitoring Records.................................................................................................................... 134 8. Self-inspections............................................................................................................................................ 135 B. OBSOLETE AND SUPERSEDED RECORDS FROM THE LABORATORY.............................................................. 135 1. Obsolete Exposure Information................................................................................................................ 135 2. Other Obsolete Documents....................................................................................................................... 135 3. Records from Decommissioned Laboratories......................................................................................... 135 C. EH&S RECORDS..................................................................................................................................................... 135 1. Records Concerning Individuals................................................................................................................. 135 2. Centralized Records..................................................................................................................................... 135 SECTION 9 – EMERGENCY PREPAREDNESS AND RESPONSE........................................................................................ 137 A. BEFORE AN EMERGENCY..................................................................................................................................... 138 1. Planning and Prevention............................................................................................................................. 138 2. Spill, First Aid and Disaster Kits.................................................................................................................. 142 B. RESPONSE TO SPECIFIC INCIDENTS / ACCIDENTS........................................................................................... 144 1. Accidents Causing Serious Personal Injury or Exposure........................................................................ 144 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS Page 10 of 213 ￜ December 2. 2023 Exposure...................................................................................................................................... 144 Chemical 3. Fires and Explosions.................................................................................................................................... 145 4. Spills............................................................................................................................................................... 145 5. Earthquake Response.................................................................................................................................. 146 6. Gas Leaks or Other Odors.......................................................................................................................... 146 7. Utility Outage................................................................................................................................................ 147 8. Laboratory Floods........................................................................................................................................ 149 9. Inclement Weather...................................................................................................................................... 149 10. Intruders, Suspicious Packages, and Demonstrators............................................................................. 149 SECTION 10 – LABS: MOVE IN / MOVE OUT.................................................................................................................... 151 A. MOVE IN: OCCUPYING A NEW OR REMODELED LABORATORY...................................................................... 152 1. Move Planning.............................................................................................................................................. 152 2. Relocation Completion................................................................................................................................ 152 3. Checklist: Moving Into a Laboratory.......................................................................................................... 153 B. MOVE OUT: VACATING A LABORATORY............................................................................................................ 153 1. Responsibilities............................................................................................................................................ 153 2. Transportation Requirements and Logistics............................................................................................ 154 3. Checklist: Laboratory Move Outs............................................................................................................... 155 APPENDIX A:296-828 WAC (WASHINGTON ADMINISTRATIVE CODE)......................................................................... 157 APPENDIX B – GLOSSARY.................................................................................................................................................. 159 APPENDIX C: TEMPLATES – LAB SPECIFIC INFORMATION............................................................................................ 179 A. LABORATORY-SPECIFIC INFORMATION............................................................................................................. 180 B. LABORATORY FLOOR PLANS............................................................................................................................... 180 C.TRAINING DOCUMENTATION FORMS...................................................................................................................... 181 APPENDIX D - STANDARD OPERATING PROCEDURES (SOP) TEMPLATES.................................................................. 187 A. LIST OF STANDARD OPERATING PROCEDURES (SOP) TEMPLATES................................................................ 188 B. BLANK STANDARD OPERATING PROCEDURE (SOP) TEMPLATE FOR CHEMICALS....................................... 188 C. FORMALDEHYDE STANDARD OPERATING PROCEDURE (SOP) FORM........................................................... 188 APPENDIX E – CHECKLISTS................................................................................................................................................ 189 A. EARTHQUAKE PREPARATION CHECKLIST FOR LABORATORY PERSONNEL.................................................. 190 1. Preparing for a Major Earthquake..................................................................................................................... 190 2. Operations after a Major Earthquake....................................................................................................... 191 B. MOVING IN/NEW LABORATORY CHECKLIST..................................................................................................... 192 1. General Safety.............................................................................................................................................. 192 2. Emergency Planning.................................................................................................................................... 192 3. Facilities/Equipment.................................................................................................................................... 192 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS December 2023 ￜ Page 11 of 4. Chemical Safety............................................................................................................................................ 193 5. Biological Safety and Animal Research..................................................................................................... 194 6. Radiation Safety........................................................................................................................................... 194 7. Hazardous Waste......................................................................................................................................... 195 8. EH&S Training............................................................................................................................................... 195 APPENDIX F - CONTACTS FOR LABORATORY PERSONNEL........................................................................................... 197 A. CALLING FOR ASSISTANCE.................................................................................................................................. 198 B. ONLINE SAFETY RESOURCES............................................................................................................................... 204 APPENDIX G: CHEMICAL STORAGE GUIDANCE BASED ON GHS LABELS.................................................................... 211 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL TABLE OF CONTENTS Page 12 of 213 ￜ December 2023 This page has been intentionally left blank. Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL EMERGENCY INFORMATION December 2023 ￜ Page 13 of 213 EMERGENCY INFORMATION Telephone Responsible Party /Supervisor: Building Coordinator: Custodial or Environmental Services: UW SEATTLE CONTACTS University of Washington (UW) Police (On Campus) 911 Seattle Fire Department (On Campus) 911 Employee Health Center 206.685.1026 Seattle Campus, South Lake Union 206.897.1327 Harborview 206.744.3081 ENVIRONMENTAL HEALTH AND SAFETY (EH&S) EH&S Main Office (Seattle) 206.543.7262 Research and Occupational Safety section (Seattle) 206.221.7770 Tacoma Campus, EH&S Manager 253.692.4425 Bothell Campus, EH&S Liaison 425.352.3763 AFTER HOURS, WEEKENDS AND HOLIDAYS UW Police (On Seattle Campus) 911 Seattle Fire (On Seattle Campus) 911 Environmental Health and Safety Staff-On-Call Page through 206.685.UWPD SITE-SPECIFIC EMERGENCY CONTACTS Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL LABORATORY-SPECIFIC INFORMATION Page 14 of 213 ￜ December 2023 LABORATORY-SPECIFIC INFORMATION This Laboratory Safety Manual serves as the Chemical Hygiene Plan (CHP) belonging to: Laboratory Name: Chemical Hygiene Officer (CHO)*: Department: Phone: * The Chemical Hygiene Officer (CHO) is the Responsible Party (RP), Faculty Member, or Supervisor who is responsible for the Chemical Hygiene Plan (CHP) in the unit or laboratory. This CHP covers the following laboratory spaces: Building(s): Room #(s): Shared Rooms and Common Areas (include building and room #): Names of PI(s)/Lab(s) that share the space(s): This CHP, consisting of the UW Laboratory Safety Manual and our laboratory-specific information, was reviewed and updated (required annually): On: By: Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL LABORATORY-SPECIFIC INFORMATION December 2023 ￜ Page 15 of 213 Items listed below identify the laboratory-specific information included in this file or stored in the following location: Use checkmarks to indicate the item has been included, reviewed and updated as needed. Check the Chemical Hygiene Plan Components box if included Laboratory-specific information cover sheet (i.e., these pages) (required) Laboratory floor plan(s) (required) General laboratory safety rules, applicable throughout the laboratory Training records, including EH&S and lab-specific trainings (required) Standard Operating Procedures (SOPs), or location if filed separately (required) MyChem Chemical Inventory Report, or location if filed separately (requ ired) Locations of Safety Data Sheets (SDSs), (required) University or departmental safety rules that apply, equipment maintenance manuals, other documents (e.g., building evacuation plan or departmental health and safety plan) if filed separately from this CHP, etc., other reference materials Equipment maintenance and repair documentation/logs Designations of individuals performing particular tasks (e.g., checking first aid supplies, maintaining chemical inventories, etc.) Authorizations for individuals to use specific hazardous/controlled substances Any special instructions for receiving and storing hazardous materials Contents of chemical spill kit(s) Any special instructions for labeling containers Self-inspection records are stored in this file, on the laboratory survey dashboard, or another location (specify): Conducted on: By: Self-inspections are required at least once a year for the laboratory spaces covered by this CHP. Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL LABORATORY-SPECIFIC INFORMATION Page 16 of 213 ￜ December 2023 Personnel list for the lab (include all staff and students): Name UW NetID Title / Job Position Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES December 2023 ￜ Page 17 of 213 SECTION 1: LABORATORY RESPONSIBILITIES Contents A. PURPOSE................................................................................................................................................... 18 1. Chemical Hygiene Plan (CHP).............................................................................................................. 18 2. Regulations Pertaining to the Chemical Hygiene Plan..................................................................... 18 3. Chemical Hygiene Plan Accessibility.................................................................................................. 19 4. Other Plans and References............................................................................................................... 19 5. Applicability to Students...................................................................................................................... 19 B. SCOPE AND APPLICATION...................................................................................................................... 19 1. Chemical Laboratory............................................................................................................................ 20 2. Chemical and Non-Chemical Hazards............................................................................................... 20 C. RESPONSIBILITIES.................................................................................................................................... 20 1. Responsible Party (RP) and Chemical Hygiene Officer (CHO)........................................................ 21 2. Dean, Department Chair and Director.............................................................................................. 25 3. Employees/Students............................................................................................................................ 27 4. UW Chemical Hygiene Officer (UW CHO).......................................................................................... 28 5. Institutional Chemical and Physical Safety Committee (ICAPS)..................................................... 28 Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES Page 18 of 213 ￜ December 2023 A. PURPOSE The University of Washington (UW) has committed to create, maintain, and enhance a safe and healthful environment for all individuals associated with the institution, including students, faculty, staff, hospital patients, and visitors. This commitment is stated in UW Presidential Executive Order 55. A major part of demonstrating this commitment in chemical laboratories is documenting the safety program in the laboratory’s chemical hygiene plan. 1. Chemical Hygiene Plan (CHP) Washington Administrative Code (WAC) 296-828 requires that laboratories document their safety procedures in a Chemical Hygiene Plan (CHP). For UW chemical laboratories, the laboratory’s chemical hygiene plan is created by combining laboratory-specific information and safety requirements found in the UW Laboratory Safety Manual (LSM). Your lab’s CHP can be electronic, paper, or a mix. It must be accessible at all times to all personnel who work in areas containing hazardous chemicals. If the CHP is electronic, personnel must know where the files are located and how to access them. They must have access to the files on a computer that is retained in the space while working. For ease of electronic use, the UW Laboratory Safety Manual may be bookmarked in its entirety, or separate sections, templates, etc. can be bookmarked. When providing electronic information it must be obvious which files and documents are current. If an all-paper CHP is to be used, the lab- specific information can be filed in the front of the manual, behind the My Lab tab. The CHP must be accessible to all personnel, (i.e., it cannot be locked in an office). Laboratory- specific information such as chemical inventories, standard operating procedures (SOPs), safety data sheets (SDS) and other reference materials may be kept in the lab or elsewhere if necessary. Individuals may keep personal copies of the LSM and the lab’s SOPs, but a master index of where the complete CHP is located, identifying the current revision number or date for each part, should be easily available at all times to personnel. Information not directly associated with safety procedures, which might be difficult to replace if lost, such as training certifications, may be kept separately in locked cabinets. That location should be identified in the laboratory-specific information section. 2. Regulations Pertaining to the Chemical Hygiene Plan This generic LSM contains information applicable to all University laboratories and explanatory materials to comply with regulations. Pertinent regulations covering laboratories include: a. Hazardous Chemicals in Laboratories: WAC 296-828 State of Washington regulation (WAC) 296-828, Hazardous Chemicals in Laboratories, is the primary Washington regulation covering laboratories performing chemical manipulations; it may also be referred to as the Laboratory Safety Standard. A copy of the WAC standard is provided as Appendix A of this manual. In chemical laboratories, this standard supersedes most of the chemical- safety requirements in other regulations. b. Hazardous Drug Rule Washington State promulgated WAC 296-62-500, effective in 2014, which impacts the handling and disposal of drugs used for human treatment and veterinary care. The rule details the requirements for safe handling of chemotherapy and other hazardous drugs. Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES December 2023 ￜ Page 19 of 213 c. International Fire Code US cities require compliance with the International Fire Code (IFC) and additional local requirements. For assistance with compliance, contact EH&S at 206.685.0341. d. Chemical Waste Management The UW LSM also includes information on chemical waste management in order to assist laboratories in complying with State of Washington regulatory standard WAC 173- 303, Dangerous Waste Regulations. Section 3 of the manual outlines the specifics of these requirements and describes safe disposal of hazardous chemicals. e. US Department of Homeland Security Regulations The United States Department of Homeland Security developed the Chemical Facility Anti-Terrorism Standards (CFATS) to implement the federal regulations in 6 CFR Part 27. These standards required the University to track and control specific chemicals of interest. The federal CFATS act expired in July 28, 2023 and therefore there are no requirements for laboratories at this time. The University’s MyChem chemical inventory system will continue to administratively track the chemicals of concern listed in the CFATS act. 3. Chemical Hygiene Plan Accessibility The CHP must be accessible to personnel whenever the laboratory is occupied. If multiple rooms are included in the laboratory, the plan must be available withouthaving to get a key from another person or leaving the lab space. It must also be available on request to UW EH&S staff and Washington State Department of Labor and Industries (L&I) representatives. 4. Other Plans and References This CHP is a part of a complete safety program. Other University documents impacting laboratory operations may include the UW Radiation Safety Manual, Biosafety Manual, Laser Safety Manual, Field Operations Safety Manual, or the Diving Safety Manual. Research conducted in the field should align with requirements and guidance listed in the UW Field Operations Safety Manual. External to the University, agencies providing grants may require additional plans and certifications to be part of the safety program. 5. Applicability to Students It is the policy of the University that students in laboratories, while not legally covered under these procedures, are afforded the same level of protection as University employees. (Students who are not employees are not covered by Workers' Compensation in the event of an injury.) B. SCOPE AND APPLICATION In general, the policies and procedures in the LSM apply at all locations that serve as assigned workplaces and educational settings for UW faculty, staff, and students. This includes the Seattle, Bothell, and Tacoma campuses, and other University-owned property, University-leased space, and temporary field locations that are under the control and supervision of UW personnel. Any laboratory that meets the definition of a chemical laboratory (refer to B.1), must complete a CHP by adding laboratory-specific information to this manual. Laboratories that do not meet the definition of a chemical laboratory may refer to this manual for general safety information but must comply with industry regulations concerning chemical management. Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES Page 20 of 213 ￜ December 2023 1. Chemical Laboratory A chemical laboratory is defined as an area (single room, a group of rooms, or a part of a room identified as a particular researcher’s laboratory), where chemical manipulations are done for research, educational, or clinical purposes. The manipulations must involve multiple hazardous chemicals or procedures involving hazardous chemicals done on a small scale (one person can easily handle the volume of the chemical in use). According to WAC 296-828, a chemical laboratory must also utilize safety practices or safety equipment to reduce the risks of the hazardous chemicals. In addition, the chemical laboratory may not be a production-type facility where one process is performed repeatedly to produce a product for others. 2. Chemical and Non-Chemical Hazards Hazardous chemicals are those which either present or could cause a health hazard such as an acute skin burn from a corrosive acid or a disease from a chronic, long-term exposure, or a physical hazard from a chemical action such as a fire or explosion. Hazardous chemicals can often be identified from their labels, which could state “Danger,” “Warning,” “Caution” or words to that effect, or the label could have a symbol which indicates a hazard. The chemical’s SDS may also indicate that the chemical has dangerous properties, that the chemical could cause some disease or injury, or that personal protective equipment, such as gloves, is recommended when handling the chemical. In addition to chemical hazards, this LSM provides information about general hazards (e.g., electrical safety, high noise, etc.) which may be present in the laboratory environment. Appendix B is a glossary of useful terminology applicable to this manual and related to both chemical and non- chemical hazards. It would be impossible for one manual to provide complete information about all potential hazards and controls, so use of other references is encouraged. For example, refer to Prudent Practices in the Laboratory: Handling and Management of Chemical Hazards (National Research Council Committee on Prudent Practices for Handling, Storage, and Disposal of Chemicals in Laboratories). This document is accessible with a UW NetID. The EH&S website contains information about environmental, health and safety policies and procedures for all UW work areas, not just laboratories. Specific policies and procedures may be found in: Control of biological hazards in the UW Biosafety Manual: Research diving in the UW Scientific Diving Safety Manual: Laser safety in the UW Laser Safety Manual: Control of radioactive hazards in the UW Radiation Safety Manual: C. RESPONSIBILITIES Information about the appropriate actions to support safe laboratory environments, organized by level in the University organization, can be found in the UW Laboratories Safety Responsibility Matrix. Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES December 2023 ￜ Page 21 of 213 1. Responsible Party (RP) and Chemical Hygiene Officer (CHO) Each chemical laboratory must have a single Responsible Party (RP), who is most often the Principal Investigator (PI) or Director. The RP is an individual who is designated the authority by a University department, school or administrative unit to direct the research or teaching program or project. The RP has scientific and technical direction for the research or activities in the lab space. The RP has the responsibility and authority to enforce safety regulations and policies; this includes ensuring that the facilities are appropriate for the research conducted. Based on State requirements, each chemical laboratory must also have a designated CHO who is knowledgeable about the laboratory’s procedures, is actively involved or observant of those procedures performed, and has the authority to enforce correct procedures. In research and teaching laboratories, the RP is the CHO by default. If the RP has other commitments that prevent knowledge of the laboratory’s day-to-day activities, they may delegate that role to a person in their laboratory who is appropriately experienced and trained. This may be a laboratory supervisor, manager, or other senior-level person with authority familiar with activities within the laboratory. The CHO must be identified by name in the laboratory-specific section of the lab’s CHP. If the RP assigns another person to be the laboratory’s CHO, the RP is still the responsible party for the laboratory. The CHO must ensure that laboratory-specific information is documented in the CHP and that activities conducted within the laboratory are consistent with the CHP. To aid in compiling laboratory-specific information, a template and guides for laboratory-specific information are available at the beginning and in Appendix C of this manual. This template also makes it easier to identify the CHO by name and to remember when the annual review of the CHP is due. The laboratory’s RP must ensure the following is accomplished: a. Develop the CHP A chemical laboratory must have a CHP. It consists of the UW Laboratory Safety Manual plus laboratory-specific information. Major areas of the laboratory-specific information portion include: The safety requirements, either as laboratory rules or standard operating procedures (SOPs), including PPE requirements Laboratory-specific topics, including hazardous environments, materials and equipment used, covered in the laboratory’s training program Additional details specific to the laboratory and generally described on the laboratory-specific information at the beginning of the LSM b. Create a List of Chemicals Stored in the Laboratory An accurate list of chemicals must be entered into the UW MyChem inventory management system and reviewed annually, at minimum. If they are not already online, upload SDSs to the MyChem Inventory when received in the laboratory. MyChem procedures are described in Section 2.B of the UW Laboratory Safety Manual. Additional information can be found on the EH&S website. c. Identify Hazards and Assess Risk The laboratory’s RP must ensure all laboratory staff understand that new and changed procedures must be assessed for hazards. The laboratory’s RP, CHO, or another person familiar with the laboratory’s procedures must assess those procedures and determine controls to adequately minimize risks. Any laboratory member can identify hazardous conditions that could result in personal injury or property damage. Once identified, the hazardous conditions and level of risk must Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES Page 22 of 213 ￜ December 2023 be assessed. Steps in the assessment include: 1. Research chemicals and processes to be used. 2. Identify and evaluate all types of hazards involved. Some evaluations to consider: what are the hazards? What is the worst that can happen? What can be done to prevent that? What can be done to minimize each risk? What should be done if something goes wrong? 3. Consider if additional hazards may be present, if scaling up 4. Select controls to adequately lower the perceived risks, using the hierarchy of controls (starting with the most effective): Eliminate hazardous substances and hazardous steps in the process (if possible), Substitute with less-hazardous chemicals, smaller quantities, and safer processes, Implement engineering controls, such as local ventilation or remote controls, Implement administrative controls, such as an after-hours policy during exceptionally hazardous processes As a last line of defense, assess PPE requirements Refer to our website for additional guidance on general PPE practices. Additional information on hazard identification can be found in the document: Identifying and Evaluating Hazards in Research Laboratories: Guidelines Developed by the Hazards Identification and Evaluation Task Force of the American Chemical Society’s Committee on Chemical Safety, 2013. 5. Ensure emergency response situations have been addressed: Hazards identified and assessment of risk should be documented for any new procedures, practices, or spaces involving usage of hazardous chemicals or materials. A risk assessment tool and guide are available on our website. If the assessment results in requirements for controls, those requirements must be documented in lab protocols (as described in the following paragraph). For best practices, it is recommended that the assessment be documented whether or not controls are required. d. Document and Enforce Appropriate Safety Practices Safe work practices and rules required within the laboratory must be documented. Requirements can be documented as “general lab rules” (Section 2 of this manual) conspicuously posted in the laboratory or included in lab protocols or SOPs (Section 6). If an individual fails to follow the requirements, the laboratory’s RP must initiate enforcement actions and document those actions. Document lab hazard assessments and risk mitigation strategies in place for new or routine work. Update documents when any changes are made to the work, including change of location. Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES December 2023 ￜ Page 23 of 213 e. Ensure Signage/Labels in Place Appropriate signage must be posted, and hazardous material containers (including hazardous waste containers) must be labeled. Laboratory signage is described in Sections 2.A.6 and 4.C; labeling is described in Section 2.E of this manual. f. Assess, Provide and Document Training The laboratory’s RP must ensure that training requirements for personnel are determined depending on their duties. Employees, volunteers, visiting scientists, and students working in the laboratory must receive general and laboratory-specific training, including the hazards of the chemicals present, and the required safety procedures including proper use of PPE. The department (or others) may provide information about the UW’s general requirements such as the UW Accident Prevention Plan and emergency response procedures. Laboratory staff are responsible for training requirements concerning the materials and the processes conducted within the laboratory; the assessment and training must be documented. Details are available in Section 7 of this manual. A matrix that provides information about mandatory and recommended classes is available on our website. g. Ensure Staff Have Access to Safety Information All personnel who work in areas with hazardous chemicals must have access to essential safety information while they are at work, including the CHP, SDSs and the regulation WAC 296-828, Hazardous Chemicals in Laboratories). This information should be available in the laboratory space where work is performed. (Note: The CHP includes the UW LSM and laboratory-specific information such as SOPs and the chemical inventory. The regulation is Appendix A of the UW LSM.) h. Ensure Visitor Safety 1. Before starting any chemical use, visiting scientists and volunteers performing procedures within the laboratory must receive equivalent training as other employees on the hazards and safety precautions, including requirements for use of PPE. 2. Visitors, such as emergency responders, facilities workers and contractors, must be protected from the hazards within the laboratory (e.g., surfaces and equipment must be decontaminated and cleaned prior to allowing visitors to contact such surfaces and equipment.) Information about preparing work areas and equipment for servicing by maintenance personnel is in Section 4.G of this manual and online. Information about decontaminating equipment and facilities for disposal or lab relocation is in Section 4.H. i. Enforce Restrictions on Children and Minors In accordance with University of Washington Administrative Policy Statement 10.9 , the laboratory must not be used as a childcare area. Minors (ages 14-17) working in the laboratory as volunteer workers or as employees must not be exposed to agents that pose higher health risks as described in WAC 296-125-030 and the U.S. Department of Labor Child Labor Provisions. These risks include such materials as human body fluids, radioactive and hazardous substances, or jobs requiring PPE other than gloves, boots, eye protection or hard hats. Refer to our website for more information, Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES Page 24 of 213 ￜ December 2023 There are specific student-learner exemptions that apply to minors (ages 16 and 17) if the work or volunteer appointment is part of a vocational education program, or if the minor is enrolled in a UW academic course for credit. For questions about the regulatory exemption, contact EH&S at 206.543.7262 and refer to the EH&S website. j. Enforce Restrictions on Pets WAC 478-128 prohibits pets in all University facilities. Staff are prohibited from bringing pets into any University facility, including laboratories. Refer to WAC 478-128. Information on UW policies regarding service animals can be found here. UW Administrative Policy Statement 46.6 affords individuals with disabilities who require the assistance of a service animal equal opportunity to access University property, courses, programs, and activities. A service animal may be restricted from specific areas of the University when consistent with other University policies, state, and/or federal laws/regulations. Examples of these areas may include: Food preparation areas Animal research facilities and grounds Medically sensitive patient and clinic areas Biologically sensitive or hazardous research sites If a service animal is restricted from certain areas, the designated disability services offices are available to assist in evaluating reasonable accommodations for the owner. If service animals are NOT restricted from a laboratory area, then the RP for that area should manage all safety needs for the animal, including any needed PPE. k. Perform Annual Reviews and Update Documents Annually, someone in the laboratory must check that revised information has been integrated into the CHP and review that conditions have not altered from a safety perspective by doing the following: Check (December, annually) for revisions to the LSM; obtain a current copy of the LSM and make it available to all personnel. Check that actual laboratory procedures and conditions remain consistent with SOPs and other laboratory-specific information. Verify your lab’s MyChem chemical inventory is current; ensure that a collection of outdated or legacy chemicals does not occur in inventory and SDSs. Review internal inspection results, routine maintenance records, and the condition of equipment used by laboratory staff to identify possible safety deficiencies, such asdirty, defective, or worn equipment, out-of-date fire extinguisher, out-of-date emergency shower inspections, etc. It is recommended that laboratory staff make any changes necessary and note the annual review date of the CHP ; maintain documentation in the laboratory-specific information section of the CHP (refer to the template ). If there are major changes duringthe year, it is recommended that laboratory staff update the laboratory-specific information as conditions or procedures change. l. Perform Accident Follow-up All accidents and incidents must be investigated. Any accidents/incidents resulting in injury to personnel to the extent that they need medical attention and accidents/incidents involving unplanned fires and explosions must be reported to the laboratory’s RP and to EH&S. It is recommended that incidents that do not result in Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES December 2023 ￜ Page 25 of 213 significant injury or damage, but do result in near misses, also be reported to the laboratory’s RP and to EH&S. Details for accident follow-up are provided in Section 9.B of this manual, including reporting requirements. If it is recognized that an SOP could be improved to mitigate risk, it must be updated prior to performing the procedure again. m. Perform Lab Safety Inspections and Assist EH&S Inspections It is expected that laboratory personnel perform formal self-inspections using a checklist or other form of documentation at least annually. The inspection checklist used by the EH&S laboratory safety team is available here. and can be augmented with additional items regarding laboratory- specific conditions. It can also be completed and stored on the lab safety dashboard. Self- inspections should be independent of any other inspections— i.e., they should not be just preparation or response for third-party audits or inspections. If safety deficiencies are identified, they must be addressed as soon as possible. Documentation of the inspections and follow-up should be maintained for three years. It is recommended that all inspections have some type of documentation, and that different people perform them to spread knowledge and gain different viewpoints. The frequency of self-inspections may vary depending on the number of safety challenges identified, and the schedule may be changed on an annual basis (especially if laboratory personnel and procedures remain constant and few new pieces of equipment are obtained). A minimum of one self-inspection should be performed annually. Additional guidance and tools for self-inspections can be found on the EH&S website. When notified of third-party inspections (for example, the EH&S laboratory safety team), the RP should be responsive in scheduling and providing laboratory-specific information as requested. Inspection findings should be addressed and corrected in the time specified (typically 30 calendar days). All laboratory staff should support the inspection to ensure lab safety. 2. Dean, Department Chair and Director The Dean, Department Chair and Director are responsible for the following: a. Ensure Safety of Laboratory Occupants “Provide a safe and healthy workplace free from recognized hazards” (WAC 296-800-110). This can be accomplished by: Being aware of the University’s Accident Prevention Program (APP). Using the Supplemental Accident Prevention Plan (SAPP) Template health and safety information for a Department health and safety plan, and address employee protections from site-specific occupational hazards that extend beyond the University of Washington Accident Prevention Plan. Ensuring personnel are oriented to the APP and SAPP. Being aware of the general requirements in this manual and other safety and health requirements, and taking a reasonable approach in minimizing hazards and risks. Ensuring lab space assigned is suitable for the intended work and has been cleaned and/or decontaminated as appropriate if the space supported previous research activities. If ventilation is needed, ensure a fume hood (or equivalent) is present and in working order. If hazardous chemicals are in use, ensure emergency washing (eyewash and shower) is available. Ensuring new lab builds or remodels are designed following the Laboratory Safety Design Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES Page 26 of 213 ￜ December 2023 Guide. Enforcing corridor policy as it pertains to lab work, equipment, and supplies. Ensuring routine inspections of emergency washing equipment, fire extinguishers, and autoclaves are performed for all labs. Orienting new RPs, visiting scientists, and postdoctoral researchers to required lab safety training and safety resources. Providing information on required authorizations as needed. Ensuring lab moves are following clean out and decontamination procedures and ensure all surplus of laboratory items follow established surplus guidelines b. Ensure Visitor Safety The department should conduct a risk assessment and develop a plan to accommodate visitors for events such as field trips or lab tours. Conduct a visitor orientation on the potential hazards and safety measures including PPE requirements for the visit. Additional topics covered may include items allowed to be handled, safety and emergency equipment available, and emergency and evacuation practices. Additional considerations apply for youth in labs which can be found on the Office of Youth Protections website. c. Enforce Laboratory Control Methods Ensure SOPs concerning use of particularly hazardous substances identify authorization requirements and maintain records of training completion. (For more information, SOP development is described in Section 6 and recommended controls are provided in Section 2.G). Ensure that safety records are maintained as described in Section 7: Safety Training and in Section 8: Record Keeping. d. Review Accidents Have procedures in place to become aware of accidents affecting laboratory operations within your department, and ensure corrective actions are taken, if necessary, to prevent accident recurrence. e. Review and Follow Up on Inspection Findings Ensure that corrective actions are completed for safety inspections. Provide a response within 30 calendar days indicating when the findings were addressed. EH&S recognizes that some findings may require longer than 30 days to correct; in these cases, a response indicating the plan for making corrections is requested. f. Ensure Appropriate Laboratory Closures/Moves Ensure laboratory closures or moves are done responsibly (Section 10). g. Assume RP duties or assure a RP is appointed for a laboratory when there is an extended absence of the PI or RP. This may be due to a RP’s sabbatical, extended remote work assignment, retirement, or illness. h. Obtain Hazardous Material Permits Hazardous Material Permits must be obtained from your local fire department (Bothell, Seattle, Tacoma, or other). Departments or building management may obtain permits covering all their laboratories. If they do not, the laboratory’s RP must ensure the permit is acquired. This is most frequently a concern when a laboratory relocates, or a new research project involves highly hazardous chemicals. Contact your Departmental Safety Officer, Departmental Administrator, or Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFETY MANUAL SECTION 1: LABORATORY RESPONSIBILITIES December 2023 ￜ Page 27 of 213 EH&S at 206.685.0341 for advice. Permits must be readily available upon request by the fire code authority. EH&S may also need to review these permits to ensure permit conditions are met. 3. Employees/Students Employees and students have a responsibility to: a. Comply with Guidelines and Policies Know and comply with lab safety guidelines and policies required for all assigned tasks. b. Report Unsafe Conditions Report unsafe conditions to your laboratory’s CHO, PI, a faculty member, your immediate supervisor, the Departmental Safety Officer, or EH&S (206.543.7262). If you identify a procedure or assigned task as being exceptionally risky, you can perform it only after you believe the risk has been reduced to an acceptable level. c. Report Accidents Report accidents and incidents to your supervisor, and to the University using the online accident reporting system (OARS). d. Use Personal Protective Equipment Select, maintain and use PPE based on the requirements and exposure assessment and consistent with your training. Students may be required to provide their own PPE for use in academic laboratories and classrooms. Required PPE must be provided at no cost to personnel, including student employees. EH&S is responsible for the following: e. Develop the Laboratory Safety Manual (and other Safety manuals, such asthe Biosafety Manual and the Laser Safety Manual) Produce and update the University Laboratory Safety Manual, which provides general information for each laboratory’s Chemical Hygiene Plan; make the manual available through the EH&S website; announce updates on the EH&S website, in the EH&S newsletters, and by email, using MyChem contacts with active inventories. f. Liaise with Regulatory Agencies Act as the liaison between the University and the regulatory agencies enforcing environmental, health and safety regulations. g. Advise Concerning Laboratory Safety Assist laboratories (as needed) with the development of the laboratory-specific information required to complete their Chemical Hygiene Plan. Act as a resource regarding laboratory safety issues. h. Perform Laboratory Inspections/Certifications/Equipment tests Conduct regular laboratory inspections and assist in implementation of self-inspection procedures. Also conduct visits, inspections, surveys, and audits as appropriate for the lab support tasked to EH&S. Test or certify laboratory equipment (such as fume hoods, laminar flow hoods, and biosafety cabinets) on the schedules described in relevant EH&S SOPs. i. Maintain a Safety Data Sheet (SDS) Database Maintain an online SDS database that is available to the campus community. The MyChem database system also contains department-maintained chemical inventories, responsible parties and contacts, caution signs for visitors and emergency personnel, and a list of surplus chemicals. Environmental Health & Safety | www.ehs.washington.edu | LABORATORY SAFET

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