Topic 8 Drugs affecting the Hematologic System PDF
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This is a quiz on drugs affecting the Hematologic System. It contains multiple-choice questions with rationale for answers. The quiz seems to be for a professional medicine course.
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Performance Exit Topic 8 Drugs affecting the Hematologic System Due Jun 30, 2024 by 11:59 pm Final Score 17% 6 out of 35 questions answered correctly...
Performance Exit Topic 8 Drugs affecting the Hematologic System Due Jun 30, 2024 by 11:59 pm Final Score 17% 6 out of 35 questions answered correctly Completed on Jun 30, 2024 10:53 pm Incorrect (29) Report content error Which statement by the nurse explains the reason for Which statement by the nurse explains the reason for discontinuing aspirin 7 days before surgery? “Aspirin has prolonged platelet activity.” “Aspirin can interact with the anesthesia.” “Aspirin has prolonged anticoagulant activity.” “Aspirin can interact with postoperative pain medication.” Rationale Aspirin is classified as an antiplatelet drug with prolonged platelet activity. This can pose an increased risk for bleeding during surgery. Thus the statement by the nurse that aspirin has prolonged platelet activity explains the reason for discontinuing aspirin 7 days before surgery. Aspirin is not known to interact with anesthesia. Aspirin is not an anticoagulant and therefore does not have prolonged anticoagulant activity. Aspirin is not known to interact with postoperative pain medications. p. 539 Report content error Which patient(s) cannot safely receive clopidogrel? Select all that apply. One, some, or all responses may be correct. Some correct answers were not selected A patient with thyroid cancer A patient with an active gastrointestinal (GI) bleed A patient with type 2 diabetes mellitus A patient with gout A patient with an intracranial hemorrhage Rationale Clopidogrel is an antiplatelet drug that works by inhibiting platelet aggregation and prevents adenosine diphosphate (ADP) from binding with the ADP platelet receptor. Clopidogrel is contraindicated in active bleeding, so a patient with an active GI bleed and a patient with an intracranial hemorrhage cannot safely receive clopidogrel. Clopidogrel may be safely given to a patient with thyroid cancer, a patient with gout, and a patient with type 2 diabetes mellitus. p. 540 Report content error Which item(s) will a nurse include in medication teaching for a patient prescribed an anticoagulant? Select all that apply. One, some, or all responses may be correct. Some correct answers were not selected “It is safe to take aspirin or ibuprofen for a headache, but avoid acetaminophen.” “Use a moisturizing shaving cream to avoid nicks and cuts when shaving.” “Carry a medical identification card that includes the name of the medication and the dosage.” “Notify the primary health care provider of bruising, tarry stools, or bloody nose or gums.” “Avoid herbal and over-the-counter (OTC) drugs unless they are approved by the health care provider.” Rationale Carrying a medical identification card is recommended to promote safety while on anticoagulants. Bleeding is a side effect of anticoagulants and may present as bruising, tarry stools, or bloody nose or gums. Many herbal and over-the-counter medications interfere with anticoagulant medications and should be avoided until approved by the health care provider. Acetaminophen is appropriate to use for a simple headache, but aspirin or ibuprofen would increase the risk for bleeding. A moisturizing shaving cream is usually used with a regular bladed razor, which is to be replaced by an electric razor while on anticoagulants. p. 537 Report content error Which statement(s) by a nurse about interventions for a patient undergoing thrombolytic therapy indicates (indicate) a need for further teaching? Select all that apply. One, some, or all responses may be correct. Some correct answers were not selected “I will check for signs of hemorrhage.” “I will frequently monitor the patient’s vital signs.” “I will collect blood samples for analysis from the veins.” “I will monitor the electrocardiogram for any dysrhythmias.” “I will administer nonsteroidal antiinflammatory drugs if the patient reports discomfort.” Rationale Venipuncture or arterial sticks should be avoided in patients who are undergoing thrombolytic treatment, so the nurse’s statement about collecting blood samples from the veins indicates a need for further teaching. Aspirin or nonsteroidal antiinflammatory drugs are contraindicated when using thrombolytics, as the combination may cause bleeding, so the nurse’s statement about administering nonsteroidal antiinflammatory drugs also indicates a need for further teaching. An increased pulse rate followed by decreased blood pressure usually indicates blood loss and impending shock. Therefore recording vital signs and reporting changes at regular intervals is necessary. Hemorrhage is a serious complication of thrombolytic treatment. Signs and symptoms of active bleeding from the mouth or rectum should be checked regularly. Reperfusion dysrhythmias are common as the blood clot is dissolving, so the electrocardiogram should be monitored continuously. p. 542 Report content error Which action will a nurse take to address a patient’s request for aspirin to treat a headache if the nurse knows that the patient is receiving warfarin? Teach the patient that acetaminophen is the preferred drug for a headache. Explain that the headache is an expected side effect and will subside shortly. Administer 650 mg of acetylsalicylic acid and reassess pain in 30 minutes. Explain to the patient that aspirin is contraindicated and administer ibuprofen instead. Rationale The nurse will teach the patient that acetaminophen, not aspirin, is the drug of choice when experiencing a headache while receiving warfarin.Aspirin should not be administered to the patient to treat a headache while the patient is receiving warfarin because it would increase the patient’s risk for bleeding. Ibuprofen is not the best alternative to aspirin; acetaminophen would be preferred for pain relief. A headache is not an expected side effect of warfarin therapy. p. 537 Report content error Which explanation describes how anticoagulants work? They dissolve clots. They alter platelet function. They prevent clots from forming. They interfere with drug metabolism. Rationale Anticoagulants prevent clots from forming but do not dissolve clots that are already formed. Anticoagulants inhibit clotting by acting on clotting factors and do not alter platelets or drug metabolism. Test-Taking Tip: Once you have decided on an answer, look at the stem again. Does your choice answer the question that was asked? If the question stem asks “why,” be sure that the response you have chosen is a reason. If the question stem is singular, be sure that the option is singular, and the same goes for plural stems and plural responses. Many times, checking to make sure that the choice makes sense in relation to the stem will reveal the correct answer. p. 533 Report content error Which instruction would the nurse include in the plan of care for a patient receiving warfarin? “Do not take aspirin for pain.” “Do not eat foods with potassium.” “Avoid the use of acetaminophen.” “Increase your intake of leafy green vegetables.” Rationale A patient on warfarin should not take nonsteroidal antiinflammatory drugs (such as aspirin) for pain because this may cause increased bleeding due to antiplatelet effects. Thus the nurse would instruct the patient not to take aspirin for pain. The patient should take acetaminophen for pain, as acetaminophen will not have an effect on the clotting process. Potassium is not a concern for patients taking warfarin. The patient should not increase consumption of leafy green vegetables because these are likely to have high levels of vitamin K and could counteract the therapeutic effect of the medication. Test-Taking Tip: Because few things in life are absolute without exceptions, avoid selecting answers that include words such as always, never, all, every, and none. Answers containing these keywords are rarely correct. p. 536 Report content error Which type of drug is cilostazol? Antiplatelet Thrombolytic Anticoagulant Antifibrinolytic Rationale Cilostazol is an antiplatelet drug that works through inhibition of type 3 phosphodiesterase in the platelets and primarily lower-extremity blood vessels. It is not a thrombolytic, anticoagulant, or antifibrinolytic drug. Test-Taking Tip: Be alert for details. Details provided in the stem of the item, such as behavioral changes or clinical changes (or both) within a certain time period, can provide a clue to the most appropriate response or, in some cases, responses. p. 539 Report content error Which antiplatelet drug is also used as a vasodilator? Cilostazol Eptifibatide Abciximab Dipyridamole Rationale Cilostazol inhibits platelet aggregation and is also used as a vasodilator. It is indicated for intermittent claudication and peripheral vascular disease. Eptifibatide is used to prevent thrombosis in percutaneous coronary intervention, unstable angina, and myocardial infarction. Abciximab prevents the reocclusion of coronary arteries after percutaneous transluminal coronary angioplasty by inhibiting platelet aggregation. Dipyridamole inhibits platelet aggregation. It is used to prevent thromboembolism after myocardial infarction, which is associated with prosthetic devices. p. 539 Report content error Which laboratory value in a patient receiving intravenous heparin requires immediate action by the nurse? Platelet count of 170,000 mm3 International normalized ratio (INR) of 1.0 Blood urea nitrogen (BUN) level of 12 mg/dL Activated partial thromboplastin time (aPTT) of 120 seconds Rationale The aPTT value of 120 seconds is too prolonged and requires immediate action by the nurse. The heparin drip should be managed per the health care provider’s prescription. The typical aPTT value for a patient on anticoagulant therapy is between 1.5 and 2.5 times the control value, with the normal control value being between 20 and 35 seconds. The normal platelet range is 150,000 to 400,000, and this patient’s platelet count is within the normal range. The normal range for BUN is 7 to 20 mg/dL, and this patient’s BUN level falls within that range. The normal range for INR is 0.8 to 1.1, and this patient’s INR lies within that range. Note that heparin does not affect the INR or the BUN level. p. 536 Report content error Which statement made by a patient receiving warfarin requires immediate correction by the nurse? “I will use a soft toothbrush.” “I will take the drug at the same time each day.” “I will increase leafy green vegetables in my diet.” “I will contact my health care provider if I develop excessive bruising.” Rationale Leafy green vegetables are rich in vitamin K, which would antagonize the effects of warfarin. Thus the patient’s statement about increasing consumption of leafy green vegetables requires immediate correction by the nurse. Rather than increase the intake of these foods, the patient should maintain a consistent daily intake of vitamin K. A soft toothbrush is recommended to prevent gums from bleeding. The drug should ideally be taken at the same time each day, and if excessive bruising occurs, the patient should be counseled to contact the health care provider. p. 537 Report content error Which nursing intervention is essential for the patient receiving alteplase? Monitor blood glucose. Assess for dysrhythmias. Administer prescribed vitamin K if bruising is observed. Stop the drug if the systolic blood pressure drops below 110 mm Hg. Rationale Alteplase can cause bleeding and dysrhythmias, so assessing for dysrhythmias is an essential nursing intervention. Alteplase does not directly affect blood glucose. Vitamin K will not reverse the effects of alteplase. Vital sign changes can alert the nurse to complications; however, a systolic blood pressure below 110 mm Hg is not, in itself, cause for alarm. p. 542 Report content error Which statement made by a patient indicates an understanding of the nurse’s teaching on warfarin? “I should keep taking ibuprofen for my arthritis.” “I will shave with an electric razor.” “I should decrease the dose if I start bruising easily.” “I will double my dose if I forget to take it the day before.” Rationale Patients on warfarin are advised to shave with electric razors, as bleeding from cuts can be difficult to control. Thus the patient’s statement about switching to an electric razor indicates an understanding of the nurse’s teaching on warfarin. Ibuprofen would potentiate bleeding and would not be advised. The patient should call the health care provider if excessive bruising occurs. The patient should not double the dose of warfarin. p. 537 Report content error Which action would a nurse take to address an international normalized ratio (INR) of 6 in a patient receiving warfarin who is experiencing a bleed? Stop the intravenous (IV) drip. Monitor the INR after holding the drug. Administer protamine sulfate intravenously. Administer vitamin K1 (phytonadione) intravenously. Rationale The nurse would administer vitamin K1 (phytonadione) to the patient who is on warfarin, has an extremely elevated INR, and is bleeding. This drug would block the vitamin K–dependent clotting factors. Warfarin is given by mouth, not intravenously. Because the INR is elevated and the patient is bleeding, it would be inappropriate to monitor the INR and hold the drug, as the drug has a long half-life of 20 to 60 hours. It would take too long for the drug to be eliminated from the body. Protamine sulfate is an antidote to heparin, not warfarin. Test-Taking Tip: If the question asks for an immediate action or response, all of the answers may be correct, so base your selection on identified priorities for action. p. 536 Report content error Which patient does the nurse anticipate will receive alteplase therapy? The patient with peptic ulcer disease The patient with gastrointestinal bleeding The patient with an acute myocardial infarction The patient with a local thrombosis from a peripheral IV Rationale The best candidate for therapy with alteplase is the patient who has an acute myocardial infarction. Thus the nurse anticipates that this patient will receive alteplase therapy. Thrombolytic therapy could dissolve the clot and alleviate the myocardial ischemia and the pain. It should be administered within 3 to 4 hours or within 30 minutes after arriving at the hospital for treatment. However, benefits may be seen when administered within 12 hours after initial symptoms. Necrosis resulting from the blocked artery can be prevented or minimized, and hospitalization time may be decreased. The patient with peptic ulcer disease and the patient with gastrointestinal bleeding would have an increased risk for bleeding with this therapy. The patient with a local thrombosis would not need treatment because local thromboses are typically small and reabsorbed with local therapy. Test-Taking Tip: Watch for grammatical inconsistencies. If an option is not grammatically consistent with the stem, the alert test taker can identify it as a probable incorrect option. When the stem is in the form of an incomplete sentence, each option should complete the sentence in a grammatically correct way. p. 541 Report content error Which drugs are known as “clot busters”? Antiplatelets Thrombolytics Anticoagulants Antifibrinolytics Rationale Thrombolytics are the class of drugs that attack and dissolve a thrombus or blood clot that has already formed; thus they are called “clot busters.” Antiplatelets prevent platelets from clumping together to form a clot. Anticoagulants prevent the formation of clots, which inhibit circulation. Antifibrinolytics control bleeding by stimulating the blood-clotting mechanism. p. 533 Report content error Which step is an essential nursing intervention when preparing to administer enoxaparin sodium to a patient? Rub the administration site after injecting. Utilize the Z-track method to inject the medication. Administer the medication into subcutaneous tissue of the abdomen. Draw up the medication in a syringe with a 22-gauge, 1½-inch needle. Rationale Enoxaparin sodium is a low–molecular-weight heparin that is administered subcutaneously into the abdomen. The site should not be rubbed after injection, and the Z-track method should never be used to administer enoxaparin sodium. The use of a 22-gauge, 1½-inch needle is more appropriate for the administration of an intramuscular injection. p. 534 Report content error A patient presents to the health care provider (HCP) for a follow-up appointment after starting treatment with clopidogrel bisulfate. Which sign or symptom during the assessment indicates a complication from this medication? Fever Nausea Melena Joint pain Rationale Clopidogrel bisulfate is an antiplatelet drug that can cause bleeding. If the patient is experiencing melena, or bloody stools, the HCP should be notified about the complication. Clopidogrel bisulfate does not cause fevers, nausea, or joint pain. p. 540 Report content error Which anticoagulant is considered a low-molecular-weight heparin (LMWH)? Warfarin Apixaban Enoxaparin Argatroban Rationale Enoxaparin is an LMWH used prophylactically to prevent deep vein thromboses. Warfarin is an oral anticoagulant. Apixaban is a selective factor Xa inhibitor. Argatroban is a direct-acting thrombin inhibitor. p. 535 Report content error Which laboratory test is used to monitor warfarin therapy? Activated partial thromboplastin time (aPTT) International normalized ratio (INR) Fibrinogen Complete blood count (CBC) Rationale The INR is used to monitor warfarin therapy. The aPTT is used to monitor heparin therapy. Fibrinogen is a clotting factor. A CBC monitors platelet counts. p. 536 Report content error By which route would the nurse expect to administer clopidogrel? Orally Intravenously Intramuscularly Subcutaneously Rationale Clopidogrel is only available orally. Heparin and cangrelor are administered intravenously. Antiplatelet drugs are not administered intramuscularly due to bleeding risks. Heparin can be administered subcutaneously to prevent deep vein thrombosis. pp. 539,540 Report content error Which action would the nurse take if a patient on atorvastatin reports muscle pain and tenderness? Call the health care provider (HCP). Seek a prescription for a muscle relaxant. Instruct the patient to rest as much as possible. Advise the patient to take ibuprofen for the pain. Rationale Patients taking high doses of atorvastatin, or any statin, are at risk for myopathy and rhabdomyolysis (disintegration of striated muscle fibers). If the patient reports muscle pain or tenderness, the nurse would immediately report these symptoms to the HCP. A muscle relaxant, rest, and ibuprofen are not appropriate treatments for rhabdomyolysis. p. 546 Report content error Which nonpharmacologic method of cholesterol reduction would the nurse include in a teaching session for a group of community members? Hypnotherapy Regular exercise Increased saturated fat intake Low-sodium diet Rationale Regular exercise is a nonpharmacologic method of reducing cholesterol levels. Hypnotherapy has not been shown to be effective in lowering cholesterol levels. Reducing, not increasing, the intake of saturated fats is a nonpharmacologic method of reducing cholesterol levels. A low- sodium diet has not been shown to be effective in lowering cholesterol levels. p. 545 Report content error Which action would the nurse take if a patient who is on Which action would the nurse take if a patient who is on cilostazol reports eating licorice several times a day? Obtain a complete dietary history. Draw blood for a potassium test. Assess the patient’s breath sounds. Monitor the patient’s blood pressure. Rationale Licorice may cause hypokalemia, which can potentiate cilostazol toxicity. Thus the nurse would draw blood for a potassium test. Obtaining a complete dietary history, assessing the patient’s breath sounds, and monitoring the patient’s blood pressure would not be appropriate actions for licorice ingestion. Test-Taking Tip: Be alert for details. Details provided in the stem of the item, such as behavioral changes or clinical changes (or both) within a certain time period, can provide a clue to the most appropriate response or, in some cases, responses. p. 548 Report content error Which laboratory value would be monitored in a patient taking statin therapy? Select all that apply. One, some, or all responses may be correct. Some correct answers were not selected Cholesterol and triglyceride levels Amylase and lipase Low-density lipoprotein (LDL) levels and high-density lipoprotein (HDL) levels Prothrombin time and international normalized ratio (PT/INR) Alanine aminotransferase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT) Rationale If the patient is taking a statin, the patient’s cholesterol, triglyceride, LDL, and HDL levels would be monitored every 3 months to evaluate drug effectiveness. In addition, the patient’s ALT, ALP, and GGT levels would be routinely monitored, as statins can be hepatotoxic. Amylase and lipase are laboratory tests used to diagnose pancreatitis, so they would not be necessary for this patient. The PT/INR is used to monitor the effects of warfarin or warfarin-like drugs on blood coagulation. Thus the PT/INR would not need to be monitored in this patient. p. 546 Report content error Which underlying condition is a primary cause of peripheral Which underlying condition is a primary cause of peripheral arterial disease (PAD)? Renal disease Arteriosclerosis Protein S deficiency Hypertension Rationale The primary causes of PAD are arteriosclerosis and hyperlipidemia, resulting in atherosclerosis, after which the arteries become occluded. Renal disease is not a primary cause of PAD. Protein S deficiency is a clotting disorder that places patients at risk for deep vein thrombosis; it is not a primary cause of PAD. Hypertension is not a primary cause of PAD. Test-Taking Tip: Stay away from other nervous students before the test. Stop reviewing at least 30 minutes before the test. Take a walk, go to the library, read a magazine, listen to music, or do something else that is relaxing. Go to the test room a few minutes before class time so that you are not rushed in settling down in your seat. Tune out what others are saying. Crowd tension is contagious, so stay away from it. p. 546 Report content error Which consequence may result from abrupt cessation of a Which consequence may result from abrupt cessation of a statin? Acute myocardial infarction Acute glomerular necrosis Acute pulmonary edema Acute hepatotoxicity Rationale Abruptly stopping a statin drug could cause a threefold rebound effect that may cause death from acute myocardial infarction. Patients taking a statin drug should be taught that antihyperlipidemic therapy is a lifetime commitment for maintaining a decrease in serum lipid levels. Acute glomerular necrosis (renal failure) and acute pulmonary edema are not effects of abrupt withdrawal of statins. Hepatotoxicity may be an adverse reaction to statins, so hepatic panels should be monitored, but this is not caused by stopping treatment abruptly. p. 546 Report content error Which instruction would the nurse give to a patient to reduce the patient’s risk for adverse effects associated with atorvastatin? Select all that apply. One, some, or all responses may be correct. Some correct answers were not selected “Get an annual eye examination.” “Have regular renal function tests.” “Have your serum liver enzymes monitored regularly.” “Have your international normalized ratio monitored.” “Report any muscle weakness immediately.” Rationale The nurse would instruct the patient to get an annual eye examination, to have serum liver enzymes monitored regularly, and to report any muscle weakness immediately. An annual eye examination should be performed because there may be a risk of cataract formation with statin therapy. Serum liver enzymes should be monitored regularly because they may be elevated by statins. The patient should immediately report any muscle aches or weakness to the primary health care provider because this could be an indication of rhabdomyolysis, a potentially fatal side effect of statins. Renal function tests should be performed if there is any renal disorder; however, there is no mention of renal dysfunction in this case. The international normalized ratio should be monitored if the patient is on anticoagulant therapy; however, there is no mention of the patient receiving anticoagulant therapy in this case. Test-Taking Tip: Be alert for details about what you are being asked to do. In this question type, you are asked to select all options that apply to a given situation or patient. All options likely relate to the situation or patient, but only one or some of the options may relate directly to the situation or patient. p. 545 Report content error Which statement made by a patient about antihyperlipidemic drugs indicates an understanding of discharge instructions? “Antihyperlipidemic drugs will replace the other interventions I have tried to decrease my cholesterol.” “To maintain therapeutic blood levels, it is important to double my dose if I miss one.” “I will stop taking the drug if it causes nausea and vomiting.” “I will continue my exercise program to help increase my high- density lipoprotein levels.” Rationale The patient’s statement about continuing an exercise program indicates an understanding of discharge instructions. Patients should continue their exercise programs while on antihyperlipidemic drugs to help increase high-density lipoprotein (HDL) levels. Antihyperlipidemic drugs are an addition to, not a replacement for, the therapeutic regimen used to decrease serum cholesterol levels. The dose should never be doubled if one is missed. Nor should the drug be stopped because of side effects. Patients should not discontinue the drug without consulting the health care provider. Test-Taking Tip: Practicing a few relaxation techniques may prove helpful on the day of an examination. Relaxation techniques such as deep breathing, imagery, head rolling, shoulder shrugging, rotating and stretching of the neck, leg lifts, and heel lifts with feet flat on the floor can effectively reduce tension while causing little or no distraction to those around you. It is recommended that you practice one or two of these techniques intermittently to avoid becoming tense. The more anxious and tense you become, the longer it will take you to relax. p. 545 Correct (6) Report content error Which antidote is used for warfarin overdose? Vitamin A Vitamin B Vitamin D Vitamin K Rationale Warfarin is an oral anticoagulant that inhibits hepatic synthesis of vitamin K, thus affecting the clotting factors II, VII, IX, and X. The antidote for warfarin overdose is vitamin K, but it takes 24 to 48 hours to be effective. Vitamin A, vitamin B, and vitamin D are not affected by the oral anticoagulant warfarin. p. 536 Report content error Which oral anticoagulant requires routine coagulation monitoring? Apixaban Warfarin Dabigatran etexilate Rivaroxaban Rationale Warfarin is an oral anticoagulant that requires regular monitoring of prothrombin time and/or international normalized ratio because it prolongs clotting time. Apixaban, dabigatran etexilate, and rivaroxaban are anticoagulants that do not alter clotting time; therefore a patient on these drugs would not require routine coagulation monitoring. p. 536 Report content error The nurse is preparing to administer alteplase to a patient who presented to the emergency department and was diagnosed as having an ischemic stroke. Which question would the nurse ask prior to administering this medication? “When did you consume your last meal?” “When did your stroke symptoms begin?” “Do you have a family history of strokes?” “Do you take blood pressure medication?” Rationale Thrombolytic medications, such as alteplase, must be administered within 3 to 4 hours of the onset of symptoms. Therefore the nurse would ask the patient when the symptoms began. Alteplase can be given without regard to meals. A family medical history and a list of home medications, such as blood pressure medication, would be obtained during the history and physical assessment. This information is not needed prior to giving the medication. Test-Taking Tip: Avoid looking for an answer pattern or code. There may be times when four or five consecutive questions have the same letter or number for the correct answer. p. 541 Report content error Which medication would the nurse anticipate the health care provider prescribing for a patient with a new diagnosis of peripheral vascular disease? Aspirin Cilostazol Dipyridamole Anagrelide hydrochloride Rationale Cilostazol is an antiplatelet drug used to treat claudication and peripheral vascular disease. Thus the nurse would anticipate the health care provider prescribing cilostazol. Aspirin is used for stroke and MI prevention. Dipyridamole is used to prevent thromboembolic events in patients with prosthetic heart valves. Anagrelide hydrochloride is used to treat chronic myelogenous leukemia and polycythemia vera. p. 539 Report content error Which patient parameter is important to consider after learning that the patient has been prescribed atorvastatin? The patient takes prescription drugs with grapefruit juice. The patient takes kava kava. The patient takes lisinopril. The patient was started on penicillin for a respiratory infection. Rationale Grapefruit juice can increase atorvastatin concentrations, which can increase the risk for side effects. Thus this combination should be avoided. Kava kava, lisinopril, and penicillin are not contraindications to using atorvastatin. p. 546 Report content error Which intervention would be needed for a patient who is receiving treatment with antihyperlipidemic drugs? Test the patient’s hearing. Assess the patient’s blood pressure. Monitor alkaline phosphatase (ALP) levels. Put the patient on a low-sodium, high-fat diet. Rationale The nurse would monitor laboratory tests for liver function, including alanine aminotransferase (ALT) and ALP levels, because antihyperlipidemic drugs can cause liver disorders. Antihyperlipidemic agents may cause changes to visual acuity, not hearing. Antihyperlipidemic drugs do not affect the blood pressure. Patients receiving treatment for high lipid levels would be instructed to begin a low-fat diet, not a high-fat diet. p. 546