Metabolism II Biochemistry II 2022 PDF

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Jordan University of Science and Technology

Leen Hawamdeh

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metabolism biochemistry oxidative phosphorylation energy production

Summary

This document is a set of lecture notes on metabolism. It details the stages of energy production, starting with digestion, then the formation of acetyl CoA, followed by the Krebs cycle and, finally, the process of oxidative phosphorylation which extracts electrons to produce energy molecules. The document also explains the structure and function of mitochondria, the process and important components in oxidative phosphorylation emphasizing the role of two membranes.

Full Transcript

7 Leen Hawamdeh Dua’ Al-Shrouf Nafez Au-tarboush Oxidative Phosphorylation As we said before, in this subject we are mainly discussing the stages of energy production , starting with digestion, then the formation of acetyl CoA from monomers, followed by Krebs cycle which extract electrons, and in or...

7 Leen Hawamdeh Dua’ Al-Shrouf Nafez Au-tarboush Oxidative Phosphorylation As we said before, in this subject we are mainly discussing the stages of energy production , starting with digestion, then the formation of acetyl CoA from monomers, followed by Krebs cycle which extract electrons, and in order to diverse these electrons into energy molecules , we pass through the oxidative phosphorylation (1) (2) (3)  What is oxidative phosphorylation? This process includes two reactions (oxidation and phosphorylation) coupled together in the mitochondria, so they’ll happen at the same time  The Mitochondria Firstly, let's take a closer look on the mitochondria where oxidative phosphorylation takes place and where 95% of ATP is produced, and remember one of the special properties of mitochondria is that they have two Cardiolipins are phospholipids membranes: composed of 3 glycerol molecules, Outer membrane: leaky/permeable to small molecules (MW

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