Anti-Ulcer Drugs, NSAIDs, Gout, Asthma, Antihistamines PDF

ANTI-ULCER DRUGS ‡ H-2 BLOCKERS ‡ Cimetidine, Ranitidine, Raniitidine, Famotidine, Nizatidine Nizatidine ‡ PROTON PUMP INHIBITORS ‡ KŵĞƉ KŵĞƉƌĂnjŽůĞ͕>ĂŶƐŽƉƌĂnjŽůĞ͕͞-ƉƌĂnjŽůĞƐ͟ ƉƌĂnjŽůĞ͕>ĂŶƐŽƉƌĂnjŽůĞ͕͞-ƉƌĂnjŽůůĞƐ͟ ‡ ANTACIDS ‡ N...

ANTI-ULCER DRUGS ‡ H-2 BLOCKERS ‡ Cimetidine, Ranitidine, Raniitidine, Famotidine, Nizatidine Nizatidine ‡ PROTON PUMP INHIBITORS ‡ KŵĞƉ KŵĞƉƌĂnjŽůĞ͕>ĂŶƐŽƉƌĂnjŽůĞ͕͞-ƉƌĂnjŽůĞƐ͟ ƉƌĂnjŽůĞ͕>ĂŶƐŽƉƌĂnjŽůĞ͕͞-ƉƌĂnjŽůůĞƐ͟ ‡ ANTACIDS ‡ NaHCO NaHCO3, O3, NaCO3 ‡ SUCRALFATE ‡ BISMUTH ‡ HELIDAC Bis Bismuth smuth subsalicyla subsalicylate, ate, tetracycli tetracycline ine aand nd metronidazole ‡ MISOPROSTOL NSAIDs Drug Classes: Examples Exammples propionic acid derivativee ibuprofen ibuprofen pyrrolealkanoic acid derivativee tolmeetin tolmetin phenylalk kanoic acid derivative phenylalkanoic flubiprofen flubiprofen indole derivative deerivativee indomethacin indomeethacin pyrazolone pyrazolon ne derivative phenylbutazone phenylbutazonee phenylacetic phenylace etic acid derivative diclofenac diclofenaac Fenamatee meclofenamate meeclofenamatee aacid ci d Oxicam piroxicam m naphthylacetic acidaciid prodrug prodrug nabumetone nabbumetone SSalicylate alicylate ASA ASA Drugs used in GOUT ‡ COLCHICINE ‡ acute gouty arthritis ‡ INDOMETHACIN ‡ OXAPROZIN ‡ ALLOPURINOL ‡ chronic tophaceous gout ‡ URICOSURIC AGENT ‡ PROBENECID ‡ SULFINPYRAZONE  ANTI-ASTHMA DRUGS ‡ Bronchodilators - ȕ2 agonist ʹ ͞-dZK>͟ - Methylxanthines ʹ Theophylline - Anticholinergics/Antimuscarinics ‡ Anti-inflammatory agents - Leukotriene modifiers ʹ Zileuton, Zafirluskast, Montelukast - Glucocorticoids ‡ Mast cell stabilizers ‡ Nedocromil ‡ Cromolyn Antihistamines 1. 1st Genera Generation ation Antihistamines a. Ethanolamines: Ethanolamiines: Carbonoxamine, Dimenhydrinate, Dimenhydrinate, Diphenhydramine, nhydramine,, Doxylamine Diphen Doxylamine b. Ethylaminediamines: Pyrilamine, Tripelennamine c. Pipera Piperazine: aziine: Hydroxyzine, Hydrox xyzine, Cyclizine, Cyclizine, Meclizine Meclizin ne d. Alkylamines: Alkylammines: Bromp pheniramine, Chlorp Brompheniramine, pheniraminee Chlorpheniramine e. Phenot thiazines: Phenothiazines: Promethazine Prometh hazine f. Methylpiperidine: Methylpiperiidine: Cyproheptadine Antihistamines 2. 2nd Generation Antihistamines a. Piperidines: Fexofenadine Fe exo ofenadine b. Miscellaneous: Loratidine, Cetirizine