Lupus Med Surg: Immunology PDF

Lupus Med Surg: Immunology Pathophysiology Systemic Lupus Erythematosus (SLE) is an autoimmune disorder where the body attacks itself, causing major inflammation in the skin, joints, kidneys, & heart resulting in organ failure over time, most often in the kidneys. Triggers...

Lupus Med Surg: Immunology Pathophysiology Systemic Lupus Erythematosus (SLE) is an autoimmune disorder where the body attacks itself, causing major inflammation in the skin, joints, kidneys, & heart resulting in organ failure over time, most often in the kidneys. Triggers Causes & Risks Avoid anything that can irritate the body S S S S Sun exposure/ Stress: Cause is unknown Smoking Sepsis “infection” UV radiation NCLEX TIP physical & emotional Most cases: Women 14 - 45 years. UV radiation from the sun makes it worse UV Signs & Symptoms 1. A butterfly-shaped rash Labs Creatinine = 1.3 (cheeks & nose) NCLEX TIP Creatinine over 1.3 = Bad Kidney NCLEX TIP Decreased WBC (norm: 5,000 - 10,000) 2. Fever higher than 1000F CREATININE Inflammation: Report to HCP Increased ESR (erythrocyte sedimentation rate) 3. Joints (painful & swollen) CRP (C Reactive Protein) Client Education Pharmacology AVOID the 4 Ss NCLEX TIP Steroids “-sone” Prednisone OQUINE S - Sun exposure / UV light YCHLOR HYDROX Methotrexate Immunosuppressants: S - Smoking Hydroxychloroquine Methotrexate Prednisone S - Stress: physical & emotional Infliximab Infliximab AZATHIOPRINE S - Sepsis “infection” Azathioprine (brand: imuran) IMURAN Notify the HCP for fever* Notes