Virus Subtype Characteristics PDF

VIRUS Subtype Characteristics Location Mode of Population Symptoms Diagnosis Treatment/ /Description Transmission Affected Preventio...

VIRUS Subtype Characteristics Location Mode of Population Symptoms Diagnosis Treatment/ /Description Transmission Affected Prevention Herpesviridae DNA stranded Culture via Enveloped monkey kidney Inoculation cells (24-48 hrs.) Life-long Serology (recent of body fluid persistent Ganglia (in a o Primary vs. past) – infection non-replicating infection primary infection Reactivation state) o Reactivatio & HSV-2 Do not survive n PCR for prolonged Immunofluoresc Safe sex periods in the ence - Hygiene environment confirmatory Cesarean Lesions are Tzanck smear Avoid lesion most contact (gram/wright significant Most common stain) – most source of Occasionally rapid/cheap; not infection life- Humans are diagnostic Herpes simplex virus threatening natural reservoir o Multinucleate Via direct d giant cell * Worldwide exposure to intracellular secretions eosinophilic inclusion Herpes labialis Person- Ocular Person (via H./lesion HHV-1 Herpes Gingivostom HSV-1 Trigeminal face) Children simplex atitis Mucocutaneou ganglia Fever blister Infant virus 1 Pharyngitis s Contaminate Skin lesions d objects Oral fever blister Encephalitis  Genital Active lesions herpes Asymptomati Genital, c intravaginal Anal lesions Herpes HHV-2 lesions Thigh, simplex HSV-2 Sacral ganglia Semen buttocks virus 2 Genitoherpes Infected birth lesion canal Neonatal Ruptured infections amniotic sac Meningitis Characteristics Mode of Population Treatment/ VIRUS Subtype Location Symptoms Diagnosis /Description Transmission Affected Prevention Varicella Zoster Virus (“HHV-3) Start: Face Respiratory Primary Low grade Chest/Back (1- droplets infection Children fever 2 days after) Varicella “Chicken Pox” Direct Malaise Rest of the Dries off after contact w/ Rash Live body (3-4 1 week lesions Pruritus Culture attenuated days) Serology vaccine Sensory Vesicular Immunofluoresc Hygiene /Dorsal root eruption ence Avoid Reinfection/ ganglion Tingling Tzanck/Wright/Gr contact Reactivation Thoracic Direct All ages Itch/Stabbing am Cover rash Zoster “Shingles” CN V contact w/ Fluid-filled Isolation Dries off after CN VII lesion 3-5 weeks blisters Cornea  Characteristics/ Mode of Population Treatment/ VIRUS Subtype Location Symptoms Diagnosis Description Transmission Affected Prevention Human Herpes Virus 6 (HHV-6) Xanthem subitum Latent infection (roseola in T-cells infantum/6th Virus replicates Early disease) in the salivary childhood o Benign gland Organ maculopapular Trunk Rose colored Via Saliva transplant rash Neck rash (2-5 5mm) recipients Maculopapular 3-5 days high fever Not usually pruritic, with no URT infection vesicle Lymphadenopathy Characteristics/ Mode of Population Treatment/ VIRUS Subtype Location Symptoms Diagnosis Description Transmission Affected Prevention Human Parvovirus B19 All ages Cyclical local P-2-P Ethnic Erythema outbreaks Cheeks Saliva, groups infectiosum Mild rash illness Chin Mucus, o “slapped cheek” Fades after 2-4 Limbs Sputum o Mild rash illness Usually days Trunk Blood o Lace-like rash on during late Affect RBC Vertical winter or limbs/trunk ealy spring  Characteristics Mode of Population Treatment/ VIRUS Subtype Location Symptoms Diagnosis /Description Transmission Affected Prevention Human Papillomavirus TREATMENTS: Produce Cutaneous “epithelial Mucosa Podophyllin All ages cell tumors” 5-Flurouracil Trichloroaceti c acid (TCA) Electrocauter Painless y Common or Seed warts Elevated Direct School skin contact w/ Rough children 71% warts PREVENTION: Indirect contact w/ HPV Vax fomites Young Biopsy Warts Histologic Bivalent Painful Autoinoccula adults Plantar warts Sole of feet examination 16, 18 Deep tion Adolescent s Quadrivalent 6, 11 Painless 16, 18 Face Juvenile or Flat warts Flat Trunk Ninevalent Skin-colored Children Elbows 6, 11 “Verruca vulgaris” Least Knees 16, 18 common 31, 33 Genital warts 45 Most common Sexual 52, 58 Genitals “Condylomata STD contact acuminata”  Characteristics/ Mode of Population Treatment/ VIRUS Subtype Location Symptoms Diagnosis Description Transmission Affected Prevention Poxviruses Multiply in the DNA virus cytoplasm Enveloped o Epidermis Most complex o Subcutaneous Largest CT Brick- Well-defined shaped/Ovoid areas (Factory areas) Produce eruptive Inclusion bodies skin pustules (Guarnieri’s (pocks/pox) bodies) Fever Macular Malaise Most well- o Flat, red Rash known P2P Papular Start: Mouth & Muscle ache Serious Air o Raised, red Vaccine Variola Tongue Human Headache Contagious Fomites/Con Vesicular No specific Small pox Face, arms, legs Animals Fatigue Fatal taminated o Raised, red, w/ tx Trunk, hand, feet Deep pitted, “Disease of objects liquid non- the Past” Pustular pigmented o Raised w/ pus Orthopox scars virus Scratch, bite of infected 1ST STAGE animal From Face, Mouth Eating Dry swabs PCR Monkeypox monkeys, Primary 5 days Palm, Sole infected meat Crust Smallpox- rodents reservoir: Fever Genitals, anus Using TREATMENT: like More uniform Rodents Chills Chest infected Placed on Dry ice Tecovirimat and diffused Malaise animal Headache products Muscle ache Body fluids  Respiratory Lympadeno secretions pathy Sex Cough Hug, kiss Nasal Fomites congestion Vertical Sore throat 2ND STAGE 1-3 days after fever Rash First Fever, Second raSh Vaccina Local pox Cowpox Disappear after 2-12 months Sex Hygiene Papular, pearl Contact Molluscum Anywhere Rash Don’t Mollusci waxy sports contagiosu EXCEPT the sole Children Umbilicated scratch or poxvirus Pale Fomites m and palm lesions pick lesions Firm Auto- Keep inoculation lesions covered Avoid sex Pustular Orf Parapoxvi dermatitis rus Pseudocow Milker’s pox nodule Yatapoxvi Tanapox Local pox rus  Characteristics Mode of Population Treatment/ VIRUS Subtype Location Symptoms Diagnosis /Description Transmission Affected Prevention Rubeola Virus Cough Coryza Fever Maculopapul ar rash Conjunctiviti s Fever Lymphadenit is Respiratory Reservoir: Age aerosols Humans Unrelated to 2 weeks History Droplet Antibiotics rubella incubation Virus isolation RISK for Rare under 6 Start: Head Antigen test Measles/Red measles Infectious FACTORS: complicatio MOA Whole body KOPLIK’s Spots Immunofluoresc during: Crowding ns Transplacent Laryngitis ence Skin rash Malnutriti Vaccination al IgG Pneumonia PCR Incubation on Bronchitis Serology prodrome No vax Sinusitis Otitis Encephalitis Diagnostic Subacute sclerosing panencephaliti s  Characteristics Mode of Population Treatment/ VIRUS Subtype Location Symptoms Diagnosis /Description Transmission Affected Prevention Rubella Virus Malaise Fever Anorexia Rash Coryza Conjunctivitis Adenopathy FORSCHEIMER SPOTS Lesions on Throat swab the soft palate Urine Not All ages Synovial Fluid diagnostic Infant/fet Body secretions Vaccination German Measles/ Start: Head Droplet Red rash us Serology (IgM or (live, 3 day Measles Whole body Congenital Common: IgG) attenuated) Effects: 5-9 y.o. 4-fold titer increase 1st-2nd Mon. Amniotic fluid 65-85% Sponty abortion Congenital defects 3rd Mon. 30-35% Glaucoma/C ataracts Deaf Heart disease 4th Mon. 10% Single congenital defect