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## Actions of CCK - stimulates contraction of the gallbladder and simultaneously causes relaxation of the sphincter of Oddi for secretion of bile. - stimulates pancreatic enzyme secretion - potentiates secretin-induced stimulation of pancreatic $HCO_3^-$ secretion - stimulates growth of the exocrine...

## Actions of CCK - stimulates contraction of the gallbladder and simultaneously causes relaxation of the sphincter of Oddi for secretion of bile. - stimulates pancreatic enzyme secretion - potentiates secretin-induced stimulation of pancreatic $HCO_3^-$ secretion - stimulates growth of the exocrine pancreas - inhibits gastric emptying. Thus, meals containing fat stimulate the secretion of CCK, which slows gastric emptying to allow more time for intestinal digestion and absorption ## Stimuli for the release of CCK - CCK is released from the I cells of the duodenal and jejunal mucosa by - small peptides and amino acids - fatty acids and monoglycerides. - Triglycerides do not stimulate the release of CCK because they cannot cross intestinal cell membranes.