Principles of Immunosuppression and Immunomodulation PDF
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Uploaded by SelfSatisfactionHeliotrope9824
University of Zakho
Hakar A.Kareem
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Summary
This lecture covers principles of immunosuppression and immunomodulation, including antihistamines, asthma medications, and corticosteroids. It also discusses TNF antagonists and other immunosuppressive agents.
Full Transcript
asthmaticdrugs anti histamines Vaccination enhance immunity treatment of allergy autoimmune diseases suppress immunity blocks H1 histaminereceptors produced by mast cells ana...
asthmaticdrugs anti histamines Vaccination enhance immunity treatment of allergy autoimmune diseases suppress immunity blocks H1 histaminereceptors produced by mast cells anaphylactic reactions should anti histamine uses betreated w Type I hypersensitivity reactions intramuscular Yen rhinitis adrenalinepinephr acutetype 1 allergicreactions urticaria Angioedema Anti histamine types sedative 1ˢᵗ generation chlorphenamine non sedative 2ndgeneration Loratidine pathogenic effectin a'th hToconstriction 2 3 steroids anti inflammatory immunosuppressivedrug p 2 3 6 Sodium cromoglicate block mast PnEmbra fif E Y.Ith Etion preventsdegranulati Entire.MY Yre beta 2 adrenoreceptor agonsists broncodilation chedkat monocytes suppressing macrophages non specificinflammatory cells granulocytes proinflammatory mediators produced by these cells Non-steroidal anti-in ammatory drugs inhibtifygenase I 2 3 4 TNF Infliximab Etanercept I 2 3 N 2 3 cyclophosphamide Tethleiate mycophenolate motet I 2 3 4 5 Monoclonal antibodies 3 4
