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# What is Appendicitis? ## Etiology and Pathogenesis? - Inflammation of the appendix of the cecum - Appendicitis is thought to result from obstruction of the appendiceal lumen, typically by lymphoid hyperplasia but occasionally by a fecalith, foreign body, tumor, or even worms. The obstruction leads...

# What is Appendicitis? ## Etiology and Pathogenesis? - Inflammation of the appendix of the cecum - Appendicitis is thought to result from obstruction of the appendiceal lumen, typically by lymphoid hyperplasia but occasionally by a fecalith, foreign body, tumor, or even worms. The obstruction leads to distention, bacterial overgrowth, ischemia, and inflammation. If untreated, necrosis, gangrene, and perforation occur. If the perforation is contained by the omentum, an appendiceal abscess results.