Neurotransmitters Classification PDF
Document Details
Uploaded by LivelyHexagon6175
An-Najah National University
Tags
Related
Summary
This document provides a table classifying neurotransmitters, their functions, and comments on their actions. It covers various neurotransmitters, including acetylcholine, biogenic amines, amino acids, and peptides. The table is well organized for easy reference.
Full Transcript
**[Neurotransmetters classification]** +-----------------------+-----------------------+-----------------------+ | **Neurotransmitters** | **Function** | **Comment** | +=======================+=======================+=======================+ | **Acetylcholine** | - Excitato...
**[Neurotransmetters classification]** +-----------------------+-----------------------+-----------------------+ | **Neurotransmitters** | **Function** | **Comment** | +=======================+=======================+=======================+ | **Acetylcholine** | - Excitatory at | - Use choline as a | | | nicotinic | precursor so it | | | receptor | is cholinergic | | | (skeletal muscle, | | | | autonomic | - Related to | | | ganglia) | Alzheimer's | | | | disease | | | - Excitatory or | | | | inhibitory | | | | depending on | | | | subtype of | | | | muscarinic | | | | receptor | | +-----------------------+-----------------------+-----------------------+ | **Biogenic amines** | | | +-----------------------+-----------------------+-----------------------+ | Norepinephrine | - Excitatory or | - Feel good | | | inhibitory | neurotransmitter | | | depending on | | | | subtypes of | - Increase heart | | | receptors ( alpha | rate and blood | | | and beta | pressure | | | adrenergic | | | | receptors) | | +-----------------------+-----------------------+-----------------------+ | Dopamine | - Excitatory at D1 | - Feel good | | | receptor | neurotransmitter | | | | | | | - Inhibitory at D2 | - Decreased level | | | receptor | in Parkinson's | | | | disease | | | | | | | | - Increased level | | | | in schizophrenia | +-----------------------+-----------------------+-----------------------+ | Serotonin | - Inhibitory | - Regulates | | | | attention and | | | | other cognitive | | | | functions such as | | | | sleep, eating, | | | | and mood | | | | | | | | - Too little | | | | serotonin leads | | | | to depression | +-----------------------+-----------------------+-----------------------+ | Histamine | - Excitatory or | - In CNS as | | | inhibitory | neurotransmitter | | | depending on type | | | | of receptor | - Connective tissue | | | (H1,H2,H3,H4) | (mast cell) as | | | | vasodilation | | | | | | | | - Blood cell | | | | (basophile) | +-----------------------+-----------------------+-----------------------+ | **Amino acids** | | | +-----------------------+-----------------------+-----------------------+ | GABA | - The main | - Too little GABA, | | (gamma-aminobutyric | inhibitory | epilepsy results | | acide) | neurotransmitter | | | | in brain | | +-----------------------+-----------------------+-----------------------+ | Glutamate | - The most common | - Called stroke | | | excitatory | neurotransmitter | | | neurotransmitter | | | | in brain | - Excessive amount | | | | leads to | | | | neuro-excitation | +-----------------------+-----------------------+-----------------------+ | Glycine | The main inhibitory | | | | neurotransmitter in | | | | spinal cord | | +-----------------------+-----------------------+-----------------------+ | **Peptides** | | | +-----------------------+-----------------------+-----------------------+ | Endorphin, ex; | - Inhibitory | - Natural opiates, | | enkephalins | | inhibit pain by | | | | inhibiting | | | | substance | +-----------------------+-----------------------+-----------------------+ | Substance P | - Excitatory | - Mediates pain | | | | transmission in | | | | PNS | +-----------------------+-----------------------+-----------------------+ | Somatostatin | - Inhibitory | - A gut-brain | | | | peptide | | | | | | | | - Inhibit growth | | | | hormone release | +-----------------------+-----------------------+-----------------------+ | Cholecystokinin | - Excitatory | - A gut-brain | | | | peptide | | | | | | | | - Inhibit appetite | +-----------------------+-----------------------+-----------------------+ | **Purines** | | | +-----------------------+-----------------------+-----------------------+ | ATP | - Excitatory or | - Released by | | | inhibitory | sensory neuron | | | depending on type | and injured cells | | | of receptors | | | | | - Provokes pain | +-----------------------+-----------------------+-----------------------+ | **Gases and lipids** | | | +-----------------------+-----------------------+-----------------------+ | Nitric oxide (NO) | - Excitatory or | - Vasodilator | | | inhibitory | | | | | - Its release | | | | Potentiate stroke | | | | damage | +-----------------------+-----------------------+-----------------------+ | Carbon monoxide (CO) | - Excitatory or | | | | inhibitory | | +-----------------------+-----------------------+-----------------------+ | Endocannabinoids | - Inhibitory | | +-----------------------+-----------------------+-----------------------+
