Liver Medications PDF

1 LIVER MEDICATIONS CLASSIFICATION THERAPEUTIC USES MECHANISM OF ACTION ADVERSE EFFECTS DRUG EXEMPLARS Immune Stimulants Interferons Hepatitis B and C...

1 LIVER MEDICATIONS CLASSIFICATION THERAPEUTIC USES MECHANISM OF ACTION ADVERSE EFFECTS DRUG EXEMPLARS Immune Stimulants Interferons Hepatitis B and C Proteins which are capable of modifying Flu-like symptoms (fever, muscle, aches, Peginterferon alfa-2b, the immune response. Also, stimulate chills, lethargy), bone marrow Peginterferon alfa-2a interferon receptor sites on noninvaded suppression, cardiotoxicity, dyspnea, cells to produce antiviral proteins which alopecia, GI upset prevent viruses from entering the cell. NMONICS: ABCDGH *Monitor CBC levels, and cardiac and liver function throughout therapy Antiviral Agents Antiretroviral- Hepatitis C Protease Inhibitors: Block protease Protease Inhibitors: vGI effects, changes Boceprevir, Protease inhibitors activity to render HIV particle unable to in liver function, elevated cholesterol Glecaprevir, fuse with and inject itself into a cell and triglyceride levels, redistribution of Simeprevir fat, Stevens-Johnson syndrome Antiviral Drugs Hepatitis C Inhibit viral DNA replication by Nausea, vomiting, headache, Ribavirin (Copegus) competing with viral substrates to form depression, paresthesia, neuropathy, shorter, noneffective DNA chains rash, hair loss; renal dysfunction Supplements Vitamins (Thiamine Treatment of Replaces in deficiency states, required Reactions and side effects are extremely Thiamine specifically) deficiencies. Dietary for carbohydrate metabolism. rare and are usually associated with IV supplement with GI administration or extremely large doses. disease, alcoholism, or cirrhosis. Vaccines (List which diseases in the liver have vaccines and what you should know about it)