Liver Medications: Interferons and Protease Inhibitors
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Questions and Answers

Match the liver medications with their classifications:

Peginterferon alfa-2b = Immune Stimulants Boceprevir = Antiviral Agents Ribavirin = Antiviral Drugs Thiamine = Supplements

Match the therapeutic uses with the respective medications:

Hepatitis B and C = Peginterferon alfa-2a Hepatitis C = Glecaprevir Deficiencies = Thiamine

Match the mechanisms of action with the corresponding medication types:

Modify the immune response = Interferons Block protease activity = Protease Inhibitors Inhibit viral DNA replication = Antiviral Drugs Replace in deficiency states = Vitamins

Match the adverse effects with their related medication types:

<p>Flu-like symptoms = Immune Stimulants GI effects, elevated cholesterol = Protease Inhibitors Nausea, vomiting, headache = Antiviral Drugs Reactions extremely rare = Supplements</p> Signup and view all the answers

Match the drug exemplars with their classifications:

<p>Peginterferon alfa-2a = Immune Stimulants Simeprevir = Antiviral Agents Ribavirin = Antiviral Drugs Thiamine = Supplements</p> Signup and view all the answers

Match the types of adverse effects to their descriptions:

<p>Stevens-Johnson syndrome = Protease Inhibitors Bone marrow suppression = Immune Stimulants Renal dysfunction = Antiviral Drugs Chills and lethargy = Immune Stimulants</p> Signup and view all the answers

Match the components of treatment with their associated conditions:

<p>Hepatitis C = Protease Inhibitors Nutritional deficiencies = Thiamine Viral entry prevention = Interferons Shorter ineffective DNA chains = Antiviral Drugs</p> Signup and view all the answers

Match the primary action with its associated medication category:

<p>Stimulate immune response = Interferons Block viral replication = Antiviral Drugs Support carbohydrate metabolism = Vitamins Prevent viral entry = Protease Inhibitors</p> Signup and view all the answers

Study Notes

Liver Medications: Immune Stimulants

  • Interferons are proteins that modify the immune response and stimulate interferon receptor sites on non-invaded cells.
  • Interferons produce antiviral proteins that prevent viruses from entering the cell.
  • Interferon medications are used to treat Hepatitis B and C.
  • Common adverse effects of interferon therapy include flu-like symptoms, bone marrow suppression, cardiotoxicity, dyspnea, alopecia, and GI upset.
  • Monitor complete blood count (CBC) levels, cardiac function, and liver function during interferon therapy.

Liver Medications: Antiviral Agents - Protease Inhibitors

  • Protease inhibitors are antiretroviral medications that block protease activity, rendering HIV particles unable to fuse with and inject themselves into a cell.
  • Protease inhibitors are used to treat Hepatitis C.
  • Common adverse effects of protease inhibitors include gastrointestinal (GI) effects, changes in liver function, elevated cholesterol and triglyceride levels, fat redistribution, and Stevens-Johnson syndrome.

Liver Medications: Antiviral Drugs

  • Antiviral drugs inhibit viral DNA replication by competing with viral substrates to form shorter, non-effective DNA chains.
  • Antiviral drugs are used to treat Hepatitis C.
  • Common adverse effects of antiviral drugs include nausea, vomiting, headache, depression, paresthesia, neuropathy, rash, hair loss, and renal dysfunction.

Liver Medications: Supplements

  • Thiamine is a vitamin used to treat vitamin deficiencies.
  • Thiamine is required for carbohydrate metabolism.
  • Reactions and side effects from thiamine supplementation are extremely rare.

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Description

This quiz focuses on liver medications, specifically immune stimulants like interferons and antiviral agents such as protease inhibitors. Learn about their mechanisms, uses in treating Hepatitis B and C, and potential side effects. Stay informed on the importance of monitoring during therapy for effective patient management.

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