Lecture 3 Oxygen effect and Reoxygenation PDF

Summary

This document covers the oxygen effect and reoxygenation in radiation biology. It discusses radiolysis of water, hypoxia in tumours, and strategies for overcoming tumor radioresistance due to hypoxia.

Full Transcript

07/Mar/24 HSC403: Radiation Biology 07 March 2024 1 2 07/Mar/24 Radiolysis of Water 3 Peroxidation – chemical reaction between reactive forms of oxygen,...

07/Mar/24 HSC403: Radiation Biology 07 March 2024 1 2 07/Mar/24 Radiolysis of Water 3 Peroxidation – chemical reaction between reactive forms of oxygen, hydroxyl radicals, hydrogen peroxide 4 07/Mar/24 5 6 07/Mar/24 7 8 07/Mar/24 9 Blue –perfused; Red –blood vessel; green - hypoxia 10 07/Mar/24 11 12 07/Mar/24 13 14 07/Mar/24 15 16 07/Mar/24 17 18 07/Mar/24 19 20 07/Mar/24 21 22 07/Mar/24 23 24 07/Mar/24 25 26 07/Mar/24 27 28 07/Mar/24 29 30 07/Mar/24 31 32 07/Mar/24 33 34

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