Infectious Diseases MCQ Revision Questions PDF

Infectious Diseases: Revision MCQs ID1, ID2 Dr. Katherine Hargreaves Integrated Pathology 6H6Z1002 2425 In this session Learning Outcomes  POLL OPEN Has the human microbiome project results so far shown that: 1. Microbial commu...

Infectious Diseases: Revision MCQs ID1, ID2 Dr. Katherine Hargreaves Integrated Pathology 6H6Z1002 2425 In this session Learning Outcomes  POLL OPEN Has the human microbiome project results so far shown that: 1. Microbial community's functional pathways change by site 0% 2. Microbial communities are site specific 0% 3. Microbial communities share common representatives but vary 0% 4. Microbial communities show varying diversity depending on site 0% 5. All statements are correct 0%  POLL OPEN Which of these types of pathogen is non- cellular? 1. Protist 0% 2. Bacteria 0% 3. Helminth 0% 4. Fungi 0% 5. Virus 0%  POLL OPEN What does WGS stand for? 1. World genome sample 0% 2. Whole genome sequencing 0% 3. Whole gene sequencing 0% 4. Whole genome sample 0% 5. World genes sampled 0%  POLL OPEN What makes detecting microorganisms challenging? 1. Their different cell types 0% 2. Their size 0% 3. Their location in tissues 0% 4. Some have the ability to invade human cells 0% 5. All of these statements 0%  POLL OPEN What is meant by a commensal species of microorganism? 1. it is harmless 0% 2. it causes disease when conditions change 0% 3. it always causes disease 0% 4. it gives a benefit to its host 0% 5. it does not survive in a host 0%  POLL OPEN Why are antibiotics not used in treating Influenza? 1. it has resistance genes against antibiotics 0% 2. antifungals are used to treat it 0% 3. antivirals are used to treat it 0% 4. antibiotics are used to treat it 0% 5. it self resolves with no specific treatment available 0%  POLL OPEN Which is not one of Koch's postulates? 1. The agent must be cultured as a single isolate 0% 2. The agent must be present in all cases of the disease 0% 3. The agent must be inoculated into a health, non-disease state model and cause disease 0% 4. The agent must show host to host transmission 0% 5. The agent must be recovered and shown to be the same after disease occurrence 0%  POLL OPEN What is the specific mechanisms by which vaccine provides protective immunity? 1. To evoke immunological memory in T cells 0% 2. To out compete an infection caused by the circulating pathogen 0% 3. To produce antibodies in the blood for protection 0% 4. To confer novel genes to cells for resistance to invading microorganisms 0% 5. To confer novel genes for the microorganism to lose resistance 0%  POLL OPEN What step does not break the chain of transmission? 1. frequent use of hand sanistiser 0% 2. quarantine of infected individuals 0% 3. use of mosquito nets 0% 4. shaking hands 0% 5. improving sanitation of water supplies 0%  POLL OPEN What does the term microbiota mean? 1. A community of microorganisms inhabiting humans 0% 2. A community of all microorganisms' genes in a defined habitat 0% 3. A community of microorganisms in a defined habitat 0% 4. A community of bacteria inhabiting humans 0% 5. A community of all microorganism's genomes in humans 0%  Join: vevox.app ID: 159-344-597 POLL OPEN What approaches could be used to develop a vaccine against a new virus? 1. use of recombination viral particles containing antigen 0% 2. use of viral vectors containing genes for expression of antigen 0% 3. use of inactivated viruses 0% 4. use of attenuated viruses 0% 5. all of the above statements 0%  POLL OPEN Which is the least common form of anthrax? 1. cutaneous 0% 2. injected 0% 3. gastrointestinal 0% 4. inhalation 0% 5. vector borne 0%  POLL OPEN What does the pathology of infectious disease not result from? 1. damage caused to host tissues by the pathogen exiting the host 0% 2. damage caused to host tissues by the host immune response 0% 3. damage caused to host tissues by pathogen route of entry 0% 4. damage caused to host tissues by pathogen replicating 0% 5. damage caused to host tissues by pathogen acquiring nutrients 0%  POLL OPEN Which of these statements describes the prodromal phase of infection? 1. Non-specific symptoms of disease onset 0% 2. Symptomatic disease specific for that infection 0% 3. Clearance of the disease 0% 4. Recovery of patient 0% 5. Subsidence of symptoms 0%  Join: vevox.app ID: 159-344-597 POLL OPEN Which type of microorganisms typically only causes an acute infection? Vote for up to 2 choices 1. Ebola 0% 2. HIV 0% 3. HPV 0% 4. HSV 0% 5. Influenza 0% (% = Percentage of Voters)  POLL OPEN Which factor/s do not influence the resulting pathology of an infectious disease? 1. Route of transmission 0% 2. Aetiological agent 0% 3. Host immune response 0% 4. Population density 0% 5. Toxins produced by the infectious agent 0%  POLL OPEN Why are there different types of stains used in light microscopy to detect microorganisms? Vote for up to 2 choices 1. to show locations of microorganisms 0% 2. to show immune cells 0% 3. to show different types of microorganism 0% 4. to show activity of microorganisms 0% 5. to show toxins 0% (% = Percentage of Voters) Study Guide Brock Chapter Quizzes  Infection Control, 18/05/22 Revision techniques Chain of transmission 6 links.that cycle through a infection cycle from host to new host. Used to identify ways to intervene and “block” transmission (at different Stages. Occurs for any infectious disease. Cornell notes Infectious infectious agent, (microorganism), pathogens/opportunistic pathogens e.g. bacteria (E coli , C. difficile, P, aeruoginosa), protists/parasites (e.g. agent Plasmoidum falciparum), fungi (e.g. Candida albicans), viruses (e.g. Measles virus) Expand topics reservoir ( source of microorganism (environment, other host, food, water), List the main topic areas out down the Reservoir E. coli on contaminated food, in contaminated water ways such as rivers, left side of a page with plenty of space From contaminated surfaces, p. falciparum from mosquito, P.aeruginosa between. from water supplies, influenza from hosts/contaminated surfaces On the right hand side, fill in note form as Portal of exit portal of exit from reservoir (e.g. coughing/sneezing expulsion faeces/vomit much information about each topic. Shedding for direct contact, in bodily fluid loss (e.g. bite from animal) e.g. E.coli from feaces or, C. Difficile from in faeces, M tuberculosis from coughing or spitting Influenza virus as sneezing/ Add to this with the use of your notes and coughing, additional sources of information. Mode of transmission – via contact with contaminated surface (e.g. CDI – Repeat to revise the content, and be able Mode of faecal oral route) /direct contact (e.g. measles)/ through air to expand each topic to cover key transmission (E.g. inflluenza aersol ) or water (e.g. P. aeruginosa – aersol ), information. ingestion of contaminated food (e.g. E. coli – faecal oral route), vector (e.g. malaria) Portal of into new host – inhalation – onto mucus membrane, entry ingestion into mucus membrane or on endothelial layer, inoculation via A wound or direct via injection or tube such as catheter Susceptable host – the person vulnerable to infection.  Infection Science, 18/05/22, Infection control Chain of Revision techniques transmission Infectious agent Expand topics – practice activity Reservoir List the main topic areas out down the left side of a page with plenty of space Portal of exit between. Add to each key topic examples of interventions that would stop transmission at this step. Mode of transmission Portal of entry  Non-selective Molecular media Antigen Revision techniques detection Culture based Indicator media Make connections Selective media Laboratory Selective growth Create a topic mind map – place the topic or key based conditions information centre page and link key information Time areas to this. Further testing (e.g. AMR Can’t culture all microorganism Specialist personal /typing Database for comparisons Accurate – sensitivity Add to this with notes. Diagnostics Rapid Expensive Link with explanations topics. Not trained personal For difficult to culture Need to develop and test for all- microorganisms Sensitivity Can arrange more information such as Positive or negative results- Selectivity clear to interpret POCT Positive or negative Advantages/disadvantages, comparisons between results- limit information topics with separating areas. available Molecular E.g. POCT and Lab based Pros on left and Cons on right Antigen detection (antibody) Revision techniques Make connections – practice activity Spend 5 minutes on your mind map using Disease “human microbiome” as the starting topic. characteristics Next - revise for 3 minutes: Either; Discuss the topic with a neighbour. Access the lecture notes on moodle. At the end of the 3 minutes put away the notes what can you add to your mind map?  Contagious Disease 1 Microbiota 5 Microbiome Revision techniques 3 2 4 6 7 Make connections Pathogens 8 Germ theory 9 Commensals Link topics with explanations: try a template like on the right hand side. If trying to think of terms, try using those from left Choose key terms for a topic (or even topics) and hand side of notes in activity 1 write explanations for how they link. Contagious Disease: 1. Infectious agent may be part of microbiota or microbiota may offer protection against some contagious disease when in tact and health (e.g. CDI causes disease from gut dysbiosis). Disease with an infectious agent that can be transmitted between hosts, or from reservoirs to host. 2. Germ theory that contagious diseases had infectious agent responsible and this was specific for disease- causative rather than correlation. (Can be virus, bacteria, fungi, protist/parasite) Germ theory of disease rather than miasma (at the time) and that could spread between hosts/in populations from source. 3. Pathogens are term for infectious disease microorganisms causing pathological harm to host either by damage of host tissue/cells, causing subsequent symptoms of disease.