GPAT 2023 2ND SHIFT QUESTION PAPER PDF

GPAT - 2023 (2ND SHIFT) COMPLETE QUESTION PAPER WITH ANSWER KEY (Officially According to NTA) Application No: Roll No: Name: Exam Date: 22-May-2023 Exam Time: 14:30-17:30 Examination: 1. Course Code - 2. Field of Study - Phanna Chern and Allied Sub Question No.1 (Question ld 22733)...

GPAT - 2023 (2ND SHIFT) COMPLETE QUESTION PAPER WITH ANSWER KEY (Officially According to NTA) Application No: Roll No: Name: Exam Date: 22-May-2023 Exam Time: 14:30-17:30 Examination: 1. Course Code - 2. Field of Study - Phanna Chern and Allied Sub Question No.1 (Question ld 22733) Marks: 4.00 R Alkyl group in Grignard reagent sen·e as TE 1. Carbene 2. Free radical EN 3. Aromatic carbocation 4. Carbanion C 0 1 {Chosen option) 0 2 0 3 0 4 N IO Question No.2 (Question ld 22708) Marks: 4.00 SS The potential ofthe calomel electrode depends upon 1. The concentration of potassium chloride solution U 2. Concentration of mercuric chloride 3. Concentration of mercmy C 4. Membrane IS 0 1 0 2 D 0 3 0 4 I T Question No.3 (Question ld 22701) Marks: 4.00 I PA The addition of Monobasic P otassimn Phosphate to the suspended Bismuth Subnitrate particles cause the A to B O'Ning to the C. G 1. A- negatin zeta potential, B-decrease, C- adsolvtion of the negatively charged phosphate anion 2. A-positiYe zeta potentiaL B-increase, C- adsorption of the negatively charged phosphate anion 3. A-positive zeta potential, B-decrease, C- ads01ption of the negatively charged phosphate anion 4. A- positiYe zeta potential, B-decrease, C- ads01ption of the positiYely charged hydrogen anion 0 1 0 2 0 3 0 4 Question No.4 (Question ld 22713) Marks: 4.00 6/1/23, 8:00 PM View Question Paper \~Vhich of the following compound would be expected to have greatest florescence? l. 00 p 2. roN02 §- roOH R TE 3. ~ roCOOH EN 4. ~ C 0 1 0 2 N 0 3 0 4 IO Question No.5 (Question ld 22724) Marks: 4.00 SS Conversion of cyclic ketone to ring expended cyclic ester takes place by 1. Willgerodt rean·angement U 2. Michael rean·angement C 3. Lossen rearrangement IS 4. Baeyer Villiger rean·angement 0 1 0 2 D 0 3 0 4 (Chosen option) T Question No.6 (Question ld 22721) Marks: 4.00 PA Which of the following is not a sulphonamide deriYative? 1. Almotriptan G 2. Sumatriptan 3. Rizatriptan 4. Naratriptan 0 1 0 2 {Chosen option) 0 3 0 4 Question No.7 (Question ld 22735) Marks: 4.00 6/1/23, 8:00 PM View Question Paper \Vhen exposed to carbon monoxide, the base pigment of Cytochrome P enzymes absorb light at 1. 450 nm 2. 370 nm 3. 254 nm 4. 600 run 0 1 {Chosen option) 0 2 R 0 3 0 4 TE Question No.8 (Question ld - 22736) Marks: 4.00 EN Carbohydrates have hydrogen oxygen atom ratio of 1. 1 : 2 2. 3 : 1 C 3. 1 : 3 0 1 4. 2: 1 N IO 0 2 0 3 0 4 {Chosen option) SS Question No.9 (Question ld - 22726) Marks: 4.00 U Identify A , B and C in below reaction C IS D T PA 3. A = Br2 B = HCI, C = NaBH4 G 4. A = Br2 , B = KOH, C = NaBH4 0 1 0 2 0 3 0 4 Question No.1 0 (Question ld - 22728) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Identify intermediate fonns in following substitution reaction. CI NH~ ? NH~ OH O H NH3 N~ 1. Cyclohexa-1.3-dien-4-yne 2. Cyclohexa-1 ,3-dien-5-yne 3. Cyclohexa-1,4-dien-5-yne R 4. Cyclohexa-1. 5-clien-3-yne 0 1 TE 0 2 0 3 0 4 EN Question No.11 (Question ld - 22705) Marks: 4.00 C Match List I with List II LIST I LIST II II Name of the drug: (Chemical class) A. B. Zolpidem Zaleplon I. II. Cyclopyrrolone Benzodiazepine N IO C. Zopiclone III. Imidazopyridine D. Triazolam IV. Pyrazolopyrimidine Choose the correct answer fi·om the options given below: SS l. (A)-(IV): (B)-(III); (C)-(II): (D)-(I) 2. (A)-(II); (B)-(IV): (C)-(III); (D)-(I) U 3. (A)-(III) : (B)-(IV); (C)-(I) : (D)-(II) C 4. (A)-(I); (B)-(III): (C)-(IV): (D)-(II) IS 0 1 0 2 D 0 3 {Chosen option} 0 4 T Question No.12 (Question ld - 22725) Marks: 4.00 PA Addition ofHBr to 1.3-butadiene at 40 oc yields G 1. 80% 1,4-addition product and 20% 1,2-addition product 2. 80% 1,2-addition product and 20% 1.4-addition product 3. 80% 1.2-addition product and 20% 1,3-addition product 4. 80% 1,2-addition product and 20% 1,3-addition product 0 1 0 2 0 3 0 4 6/1/23, 8:00 PM View Question Paper Question No.13 (Question ld 22722) Marks: 4.00 \Vhich heterocyclic ring is fitsed to a steroidal nucleus in Danazol? 1. Thiazole 2. Isoxazole 3. Imidazole 4. Pyrazole 0 1 (Chosen option) R 0 2 0 3 TE 0 4 Question No.14 (Question ld - 22727) Marks: 4.00 EN Which of the following facto r make carbonyl group in acyl compounds. too, susceptible to nucleophilic at1ack? C 1. The tendency of oxygen to acquire electrons eYen at the expense of gaining positiYe charge 2. The tendency of oxygen to acquire electrons even at the expense of gaining negati\'e charge N 3. The tendency of carbon to loose electrons even at the expense of gaining negative charge IO 4. The tendency of carbon to loose electrons even at the expense of gaining positive charge 0 1 SS 0 2 0 3 0 4 U Question No.15 (Question ld 22715) Marks: 4.00 C In atomic absorption spectroscopy, back ground correction perfonned using a single hollow cathode lamp IS pulsed first with a low current and then with a high current is called 1. Smith Hieftje background C011'ection D 2. Continuous source background COITect.ion T 3. Zeeman effect background con·ection PA 4. Hollow cathode background correction 0 1 0 2 G 0 3 0 4 Question No.16 (Question ld - 22729) Marks: 4.00 Phenol reacts with chloroform in presence of aqueous sodimn hydroxide to give chief product? l. 2-Chloro Benzaldehyde 2. 2-Hydroxy Benzaldehyde 3. 3-Hydroxy Benzaldehyde 4. 3-Chloro Benzaldehyde 6/1/23, 8:00 PM View Question Paper 0 1 0 2 0 3 0 4 I Question No.17 (Question ld - 22730) Marks: 4.00 Replacement of the diazonium group by halogen in presence of copper powder is 1. Sandmeyer reaction 2. Gattennatm reaction R 3. Hofmann reaction TE 4. Gabriel reaction 0 1 0 2 EN 0 3 0 4 C Question No.18 (Question ld - 22702) Marks: 4.00 Which of the following ICH Harmonized Tripattite Guidelines related to stability, provides the general N requirements for stability. testing of new drug substances and products? IO 1. QlA (R2) 2. QlB SS 3. QlD 4. QlE U 0 1 0 2 C 0 3 0 4 IS Question No.19 (Question ld - 22714) Marks: 4.00 D All the following about back titration are true, EXCEPT T 1. It is perfonned when the rate of reaction between the analyte and reagent is fast. PA 2. It is perfonued when the rate of reaction between the analyte and reagent is slow. 3. It is performed when the standard solution lacks stability. G 4. It is the process in which excess of standard solution used to react with an analyte is determined by titration with a second standard solution. 0 1 0 2 0 3 0 4 I Question No.20 (Question ld - 22737) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Identify pair of C4 epimers. 1. D-glucose and D-galactose 2. D-glucose and D-fmctose 3. D -glucose and D-matmose 4. D -glucose and D-xylulose 0 1 0 2 R 0 3 0 4 TE Question No.21 (Question ld - 22732) Marks: 4.00 EN _ _ is an example of aromatic nucleophilic substitution reaction. 1. Chichibabin C 2. Gattennan Koch reaction 3. Kolbes reaction 4. Friedei-Crafts reaction N IO 0 1 0 2 0 3 {Chosen option) SS 0 4 Question No.22 (Question ld - 22719) Marks: 4.00 U Amphetamine undergoes one of tJ1e following metabolic reaction to convert to 1-phenyl-2-propanol metabolite Yia ketone fonnation C 1. hydrolysis IS 2. oxidation D 3. reduction 4. hydroxylation T 0 1 PA 0 2 0 3 0 4 G Question No.23 (Question ld - 22717) Marks: 4.00 What is the popular common name for a bioactiYe compound w ith chemical name of (m-hydroxyphenyl)- trimethyl ammonium methyl sulphate dimetJ1yl carbamate? 1. Neostigmine 2. Pyridostigmine 3. Physostigmine 4. Metastigmine 0 1 6/1/23, 8:00 PM View Question Paper 0 2 0 3 0 4 {Chosen option) Question No.24 (Question ld - 22712) Marks: 4.00 Aclu·omatograru of a peak provided a retention time at 5.4 minutes and 0.41 base vvidth of the peak. The munber of plates or the peak obtained is 1. 210.7 2. 173.5 R 3. 78.4 TE 4. 2775.5 0 1 0 2 EN 0 3 0 4 C Marks: Question No.25 (Question ld - 22718) 4.00 N \Vhich among the following Cephalosporins has an unusual 5-thio- 1,2,3 ,4-tetra zole substituent attached to core heterocyclic nucleus tluough a methylene bridge? IO 1. Cefazolin 2. Cefam andole SS 3. Cefoxitin 4. Cefadroxil U 0 1 0 C 2 0 3 IS 0 4 Question No.26 (Question ld - 2271 0) Marks: 4.00 D ·w hich one of the following mo lecules h as a dipole moment? T PA l. CS 2 2. CHC1 3 G 4. co2 0 1 {Chosen option) 0 2 0 3 0 4 Question No.27 (Question ld - 22716) Marks: 4.00 6/1/23, 8:00 PM View Question Paper In UV spectrophotometer, lamp used to generate UV spectrum is 1. Tungsten 2. Sodiwn vapor 3. 1ED 4. Deuterium 0 1 {Chosen option) 0 2 R 0 3 0 4 TE Question No.28 (Question ld - 22738) Marks: 4.00 EN Which one of the following is an example of a chelate? 1. Cisplatin 2. Hemoglobin C 3. Iodine 4. Fen·ocene 0 1 {Chosen option) N IO 0 2 0 3 SS 0 4 Question No.29 (Question ld - 22704) Marks: 4.00 U A 2.0% saline solution is C 1. Hypotonic IS 2. Hypertonic 3. Isotonic D 4. Iso-osmotic 0 1 T 0 2 0 3 PA 0 4 {Chosen option) Question No.30 (Question ld - 22731) Marks: 4.00 G The C-2 epimer ofD-glucose is 1. D-Mannose 2. 1-Fructose 3. D- Giuco pyranose 4. 1-Arabinose 6/1/23, 8:00 PM View Question Paper 0 1 0 2 0 3 0 4 Question No.31 (Question ld - 22709) Marks: 4.00 \~Vhich of the following factors affect the heat of reaction based on Kirchoff equation? 1. Molecularity 2. Temperature R 3. Pressure TE 4. Volume 0 1 0 2 (Chosen option) EN 0 3 0 4 C Question No.32 (Question ld - 22723) Marks: 4.00 Which of the following is correct order of stability of free radicals? N IO SS U 0 1 0 2 C 0 3 0 4 IS Question No.33 (Question ld - 22706) Marks: 4.00 D Following statement is correct with respect to \·oltage sensitive calcium channels : T 1. L-type Blocker : Nifedipine PA 2. T-type Blocker: Verapamil 3. N-type Blocker : Mibefradil G 4. R-type Blocker : Diltiazem\ 0 1 0 2 0 3 0 4 Marks: Question No.34 (Question ld - 22711) 4.00 6/1/23, 8:00 PM View Question Paper Predict the theoretical max value for the following compound using \Voodward-Fieser mles. Base value for the compow1d is 2 15 tun. 1. 240 lllll 2. 220 lllll R 3. 225 nm TE 4. 235 nm 0 1 0 2 {Chosen option} EN 0 3 0 4 Question No.35 (Question ld - 22703) Marks: 4.00 C EDTA is an example of 1. Unidentate Ligand N IO 2. Bidenatate Ligand 3. Tridentate Ligand SS 4. Hexadentate Ligand 0 1 {Chosen option} 0 2 U 0 3 0 4 C IS Question No.36 (Question ld 22734) Marks: 4.00 Isoquinoline on treatment with oleum at 90 °C yields majorly D 1. Isoquinoline-3-sulfonic acid T 2. Isoquinoline-5-sulfonic acid PA 3. Isoquinoline-6-sulfonic acid 4. Isoquinoline-7-sulfonic acid G 0 1 0 2 0 3 0 4 Question No.37 (Question ld - 22720) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Eicosanoids are polyunsaturated fatty acids of _ _ carbons. 1. 30 2.25 3. 15 4.20 0 1 0 2 R 0 3 0 4 TE Question No.38 (Question ld - 22707) Marks: 4.00 EN Efficiency of an reversible engine is given by 1. Clapeyron equation 2. Claussius Clapeyron equation C 3. Gibbs-Helmholtz equation 4. Camet theorem 0 1 N IO 0 2 0 3 SS 0 4 Phannaceutlcs and Allied Subjects - Marks: Question No.1 (Question ld - 22768) U 4.00 C Noye-\Vhitney's equation predicts : IS 1. an increase of dissolution rate if the particle size is reduced by micronization because of an increase in area D 2. relationship behveen the radius of the diffusing molecule and its diffusion coefficient 3. the influence of electrolyte on the rate constant T 4. an equilibrium between the surfactant and the drug molecules at the surface of the solution and in the PA bulk of the solution 0 1 (Chosen option) 0 2 G 0 3 0 4 Question No.2 (Question ld - 22772) Marks: 4.00 One of the following drugs is not meant for systemic use 1. N etilmycin 2. Sisomicin 3. Neomycin 4. Paramomycin 6/1/23, 8:00 PM View Question Paper 0 1 0 2 0 3 0 4 {Chosen option) Marks: Question No.3 (Question ld 22770) 4.00 Indicate which of the following molecular characte1istics will be expected to increase the solubility of a simple solute in an aqueous solution 1. A high melting point R 2. The presence of polar group TE 3. A high molecular smface area 4. A high boiling point EN 0 1 0 2 {Chosen option) 0 3 0 4 C Question No.4 (Question ld 22743) Marks: 4.00 N Which type of in-,·itro-in-,ivo correlation compares % dmg released Vs % drug absorbed? IO 1. LeYel C SS 2. Le\·eiA 3. Multiple level C 4. LeYel B U 0 1 C 0 2 0 3 IS 0 4 Question No.5 (Question ld 22745) Marks: 4.00 D Which of the following characteristics is most likely to be associated with a high apparent volwne of T distribution? PA 1. Penetration across the blood brain and blood testis ban·iers 2. ExtensiYe binding to plasma protein G 3. Distribution into total body water 4. Extensive binding to tissue constituents 0 1 0 2 0 3 0 4 {Chosen option) Question No.6 (Question ld 22775) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Ostwald's dilution law.is applicable to 1. weak electrolytes 2. strong electrolytes 3. non-electrolytes 4. all electrolytes 0 1 {Chosen option) 0 2 R 0 3 0 4 TE Question No.7 (Question ld - 22776) Marks: 4.00 EN Which among the following is not used as NSAID? 1. Indomethacin extended release 75 mg 2. A spirin 75 mg C 3. Naproxen 500 mg 4. Mefenamic acid 500 mg N IO 0 1 0 2 0 3 SS 0 4 Question No.8 (Question ld 22752) Marks: 4.00 U Autoimmunity refers to C 1. an automatic trigger of the immune system directed against a specific pathogen IS 2. Failure to distinguish between self and non-self 3. An automatic segregation of T and B cells D 4. F ailure of B-cells to interact with T-cells T 0 1 0 2 PA 0 3 {Chosen option) 0 4 Question No.9 (Question ld 22739) Marks: 4.00 G Ideally BA studies should be canied on _ _ Yolunteers. 1. aged 2. children 3. healthy 4. p atient 0 1 0 2 {Chosen option) 0 3 6/1/23, 8:00 PM View Question Paper 0 4 Question No.1 0 (Question ld 22750) Marb:4.00 \Vhich of the following is acellular? l. Bacteria 2. Fungus 3. Virus 4. Amoeba R 0 1 TE 0 2 0 3 0 4 {Chosen option) EN Question No.11 (Question ld 22746) Marb:4.00 Given below are two statements, one labelled as Assertion (A) and the other labelled as Reason (R) : C Assettion (A) In case of Salicylic Acid Ointment BP Wool Alcohol Ointment made with white soft paraffin is used. Reason (R) Wool Alcohol Ointment made with white soft paraffin is used because the medicament is N coloured. In the light ofthe above statements, choose the most appropriate answer from the options given below : IO l. Both (A) and (R) are true and (R) is the conect explanation of (A) 2. Both (A) and (R) are true but (R) is not the correct explanation SS of (A) 3. (A) is tme but (R) is false U 4. (A) is false but (R) is ttue C 0 1 0 2 IS 0 3 0 4 D Question No.12 (Question ld 22751) Marks: 4.00 T Recombination process in a cell occmTing through the mediation of phages is called PA 1. transfection 2. transduction G 3. conjugation 4. tt·ansfonnation 0 1 0 2 {Chosen option) 0 3 0 4 Marts: Question No.13 (Question ld 22771) 4.00 6/1/23, 8:00 PM View Question Paper In a mechanical model of a viscoelastic material, showing both viscosity of liquid state and elasticity of solid- state combined in series is termed as 1. Voigt Element 2. Creep Element 3. Maxwell Element 4. Retardation Element 0 1 R 0 2 0 3 TE 0 4 Marks: Question No.14 (Question ld 22754) 4.00 EN If S is the solubility of small particles of radius r. is the nonnal solubility (i.e., of a solid consisting of fairly large patticles). is the interfac ial energy, M is the molecular weight of the solid, p is the density of the bulk solid, R is the gas constant and T is the thermodynamic temperature, then C which of the following equation indicates the changes in interfacial free energy that accompany the dissolution of particles of vary ing sizes causing the solubility of substance to increase with decreasing patt icle size? 1. Log (S0 I S) = 2yMr 12.303RT p N IO 2. Log (SI S0 ) = 2yMr 12.303RT p SS 3. Log (S0 IS)= 2yMr 12.303RT pr U 4. Log (SI S0 ) = 2yM I 2. 303RT pr C 0 1 0 IS 2 0 3 0 4 D Question No.15 (Question ld 22766) Marks: 4.00 T M atch List I ,,,-ith List II PA List- ! List-IT (Dissolution (~a me) apparatus) A. Type l I. Reciprocating holder G B. Type 5 II. Paddled oYerdisk C. USPApp6 III. Basket type D. USPApp 7 IV \...ylinder apparatus Choose the con·ect answer from the options given below: 1. (A)-(III); (B}-(II): (C)- (IV): (D)-(I) 2. (A)-(IV): (B)-(I): (C)- (II) : (D)-(III) 3. (A)-(II): (B)-(III): (C)-(I): (D)-(II) 4. (A)-(I): (B)-(II); (C)-(III): (D)- (IV) 0 1 {Chosen option} 6/1/23, 8:00 PM View Question Paper 0 2 0 3 0 4 I Question No.16 (Question ld - 22757) Marks: 4.00 A clear. sweetened hydroalcoholic liquid containing medicament, is known as 1. Elixir 2. Symp R 3. Tincture 4. Decoction TE 0 1 {Chosen option) 0 2 0 3 EN 0 4 Question No.17 (Question ld - 22753) Marks: 4.00 C The Schick test is used to detennine susceptibility to 1. Measles N IO 2. D iptheria 3. Polio SS 4. Typhoid 0 1 0 2 {Chosen option) U 0 3 0 4 C Question No.18 (Question ld - 22742) Marks: 4.00 IS Abs01ption of Vitamin B 12 is facilitated by D 1. Hydrogel T 2. Glycoprotein PA 3. Lipoprotein 4. Mucoprotein 0 1 G 0 2 0 3 {Chosen option) 0 4 Marks: Question No.19 (Question ld - 22760) 4.00 6/1/23, 8:00 PM View Question Paper A sample of glucose was decomposed at 140° C in a solution containing 0·030 M HCl. The \·elocity constant, k. was found to be 0 ·0080 lu·- 1. If the spontaneous rate constant, is 0·0010 hr- 1, and the catalysis due to hydroxyl ions in this acidic solution is considered as negligible, then the catalytic coefficient. kH is 1. 0 ·22 per mole per hom 2. 0· 233 per mole per hour 3. 0·27 per mole per hom· 4. 0·29 per mole per hour R 0 1 TE 0 2 0 3 0 4 EN Question No.20 (Question ld - 22762) Marks: 4.00 Match List I with List II C List- 1 List- II (Name of Emulsifier) (Remark) N A. Triethanolamine ole.ate I. Surface-active agent (non-ionic) B. N-cethyl N-ethy morpholinium ethosulfate (Atlas G-263) II. ~ydrophilic colloid C. Polyxyethelene sorbitan mono oleate (Atlas Tween 80) III. Surface-active agent (aniomc) IO D. Gelatin IV. v/o Emulsifier (HLB=4.3) \'. Surface actiYe agent (cationic) SS Choose the correct ans\-.·er fi·om the options given below: 1. (A)-(II): (B)-{IV); (C)-(V): (D)-{III U 2. (A)- (III); (B)-{V); (C)-(I); (D)-{II) 3. (A)- (V): (B)-{IV): (C)-(II); (D)-{III) C 4. (A)-(IV); (B)-{III): (C)-{V): (D)-{I) IS 0 1 0 2 (Chosen option) D 0 3 0 4 T Question No.21 (Question ld - 22763) Marks: 4.00 PA Which of the following equipment is based on the principle of Pohlman liquid whistle? 1. Ultrasonifier G 2. Mechanical stin:er 3. Silverson homogeniser 4. Colloid mill 0 1 0 2 0 3 0 4 Marks: Question No.22 (Question ld - 22764) 4.00 6/1/23, 8:00 PM View Question Paper \Vhich of the following is the con·ect choice of particle size measurement teclmique in scoring order of size? a. SieYe b. Anderson Pipette c. Coulter counter d. Light scattering 1. a. b. c, d 2. b , d, c, a 3. a, c, b. d R 4. d, a. c, b TE 0 1 0 2 0 3 EN 0 4 Question No.23 (Question ld - 22747) Marks: 4.00 C ·w hich one of the following is an example of ointment prepared by trituration and containing liquids and solids? 1. Salicylic and Sulphm Ointment BPC N IO 2. Whitfield's Oitnment BPC 3. H amamelis Ointment BPC SS 4. Resorcinol Ointment Compound BPC 0 1 0 2 U 0 3 0 4 C IS Question No.24 (Question ld 22740) Marks: 4.00 Which of the following drugs does not bind to haemoglobin? D A. Chlorpromazine B. Phenobarbital C. Phenothizine T D. Phenytoin Choose the most appropriate answer from the options gi\:en below : PA l. B , C and D only 2. B and C only G 3. C and D only 4. A only 0 1 0 2 0 3 0 4 {Chosen option) Marks: Question No.25 (Question ld - 22756) 4.00 6/1/23, 8:00 PM View Question Paper ' Picking' is a term used to describe 1. Separation of tablet into two or more layers 2. The situation when the smface material from a tablet that is sticking to and being remoYed from the tablet 's surface by a punch 3. Unequal distribution of colour on a tablet 4. Patti a! or complete separation of the top and bottom crowns of a tablet from the main body of the tablet 0 1 R 0 2 {Chosen option} 0 3 TE 0 4 Question No.2& (Question ld - 22774) Marks: 4.00 EN Enzyme asparaginase is obtained from 1. Clostridium histolyticum C 2. Bacillus subtilis 3. Erwinia caratovora 4. Kluyveromycas lactis N IO 0 1 {Chosen option} 0 2 SS 0 3 0 4 Question No.27 (Question ld - 22773) Marks: 4.00 U Which of these is not a colligative property? C 1. Osmotic pressure IS 2. Depression of fi-eezing point D 3. Elention in boiling point 4. Polymotphism T 0 1 PA 0 2 0 3 0 4 {Chosen option} G Question No.28 (Question ld - 22767) Marks: 4.00 Sarong SpA semiautomatic equipment is used for the 1. Filling and packaging line for topical phannaceutical aerosols 2. Filling of hard gelatin capsule 3. Production of suppositories 4. Insetting rubber closure in vials 0 1 6/1/23, 8:00 PM View Question Paper 0 2 0 3 0 4 Question No.29 (Question ld - 22769) Marks: 4.00 Ri Hingers hypothesis relates (a) energy used in size reduction (b) new surface area produced (c) equiYalent shape (d) Reynold's number R 1. a and b TE 2. band c 3.aandc EN 4. a and d 0 1 0 2 0 3 C 0 4 Marks: Question No.30 (Question ld - 22765) N 4.00 IO Given below· are two statements : Statement I Rubber stoppers cannot \Vithstand pyrogen-destmctive temperatures. Statement II In case of rubber stopper for injections reliance must be on an effective sequence of SS washing, thorough rinsing w ith WFL prompt sterilization. and protectiYe storage to ensure adequate pyrogen control. In the light of the above statements, choose the most appropriate answer from the options given below : U l. Statement I and Statement II are con·ect C 2. Statement I and Statement II are inconect IS 3. Statement I is correct but Statement II is u1con·ect 4. Statement I is incotTect but Statement II is conect D 0 1 0 2 0 3 T 0 4 PA Question No.31 (Question ld - 22759) Marks: 4.00 In 1798 Edward Jenner published his work on _ _ G 1. Vaccination 2. Prescription writing 3. Isolation of morphu1e 4. Isolation of codeine 0 1 (Chosen option) 0 2 0 3 0 4 Question No.32 (Question ld - 22755) Marks: 4.00 6/1/23, 8:00 PM View Question Paper M atch List I with L ist II List-I List- IT (P a rts of the valve (Pm]Jose of parts) assembly) A. Gasket I..t...inks the dip tube and the stem and the actuator B. Spring II. Prevents the leakage C. Yfounting cup III. Holds the Gasket in place D. Housing IV. Holds the \"al\"e in place Choose the con·ect answer from the options g iven below: l. (A)-(III) ; (B}-(II): (C)-(IV): (D}-(I) R 2. (A}-(II): (B}-(III): (C)-(IV); (D}-(I) TE 3. (A)-(IV); (B}-(I): (C)- (II); (D}-(III) 4. (A)-(III); (B}-(I); (C)-(IV): (D}-(II) EN 0 1 0 2 {Chosen option) 0 3 C 0 4 Question No.33 (Question ld - 22744) Marks: 4.00 N IO Conjugation of a drug includes the fo llowing except : 1. Glucuronidation SS 2. Sulfate fonn ation 3. Hydrolysis U 4. M ethy lation 0 C 1 0 2 IS 0 3 {Chosen option) 0 4 D Question No.34 (Question ld - 22741) Marks: 4.00 T Absolute solubility does not rely on standard condition of PA 1. pH 2. pressure G 3. temperature 4. volume 0 1 {Chosen option) 0 2 0 3 0 4 Question No.35 (Question ld - 22758) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Modified Lo,:vTy's Procedme is used to characterize 1. Protein-Content in allergen product 2. Protein profile in allergen product 3. Potency of allergen product 4. Storage condition of allergen product 0 1 0 2 R 0 3 0 4 TE Question No.3& (Question ld - 22748) Marks: 4.00 EN Vanishing cream is an ointment that may be classified as 1. water soluble base 2. oleaginous base C 3. absorption base 4. emulsion base 0 1 N IO 0 2 0 3 SS 0 4 {Chosen option} Question No.37 (Question ld - 22761) Marks: 4.00 U In tenns of the kinetics. degradation in suspension is C 1. first order IS 2. second order 3. pseudo zero order D 4. zero order 0 1 {Chosen option} T 0 2 PA 0 3 0 4 Question No.38 (Question ld - 22749) Marks: 4.00 G 6/1/23, 8:00 PM View Question Paper \Vhile preparing the following : Rx Salicylic acid : 3g Sulfur ppt: 7g Lanolin : 1Og White petroleum : 1Og The phanuacist should : 1. use a rubber spatula to weigh and levigate the salicylic acid 2. mix the powders using geometric dilution in a m01tar R 3. place on an ointment tile and levigate the ingredients using geometric dilution TE 4. All of the above 0 1 0 2 EN 0 3 0 4 {Chosen option) Phannacognosy and Allied Subjects· C Question No.1 (Question ld 22779) Marks: 4.00 The follo\ving are adulterants of clove except one, choose the most appropriate option : 1. Mother Clove N IO 2. Clove Stalk SS 3. Blown Clove 4. Clove Bud 0 1 U 0 2 0 3 (Chosen option) C 0 4 IS Marks: Question No.2 (Question ld 22782) 4.00 D Unicellular conical, warty trichomes, paracytic stomata, xylem vessel.s with annular thickening are impmtant microscopical features of which p lant T 1. Datura metel PA 2. Cassia angustifolia 3. Digitalis purpurea G 4. Atropa belladonna 0 1 0 2 (Chosen option) 0 3 0 4 Question No.3 (Question ld 22778) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Sesquitetpenes are biosynthesised from _ _ in plants. 1. Famesyl-pyrophosphate 2. Geranyl fam esyl pyrophosphate 3. Tetpenes 4. Degraded products oftetpeues 0 1 0 2 {Chosen option} R 0 3 0 4 TE Marks: Question No.4 (Question ld - 22785) 4.00 EN The alcohol solution of Sudan-III and tincture of alkana are the reagents used for identification of following type of secondmy metabolites 1. resins C 2. alkaloids 3. fixed oils N IO 4. \'Olatile oils 0 1 0 2 SS 0 3 {Chosen option} 0 4 U Question No.5 (Question ld - 22777) Marks: 4.00 C Aloe contains _ _ type of glycosides. IS 1. C-glycosides 2. 0 -glycosides D 3. S-glycosides T 4. N-glycosides 0 1 PA 0 2 {Chosen option} 0 3 0 4 G Question No.6 (Question ld 22780) Marks: 4.00 Ayurvedic fermented prepar ation includes 1. Chumas 2. Tailas 3. Bhasmas 4. Aristas and Asa\'as 0 1 {Chosen option} 0 2 6/1/23, 8:00 PM View Question Paper 0 3 0 4 Question No.7 (Question ld - 22783) Marks: 4.00 Modified borntrager's test is used to detect the presence of which type of glycosides 1. 0 -type of glycosides 2. C-type of glycosides 3. S-type of glycosides R 4. N-type of glycosides TE 0 1 0 2 (Chosen option) 0 3 EN 0 4 Question No.8 (Question ld - 22784) Marks: 4.00 C Terpene indole alkaloid derived fi·om L-Tryptophan via secologanin is 1. Morphine 2. Codeine N IO 3. Ajamalicine 4. Thebaine SS 0 1 (Chosen option) 0 2 0 3 U 0 4 C Question No.9 (Question ld - 22786) Marks: 4.00 IS Chemically volatile oils differ from fixed oils in one of the following characters D 1. mixtures of eleoptenes and steroptenes 2. presence of flavonoids T 3. presence of plant acids PA 4. hydrophilic in nature 0 1 0 2 G 0 3 0 4 Question No.10 (Question ld ·22781) Marks: 4.00 6/1/23, 8:00 PM View Question Paper \Vhich on.: of the following drug is skeletal muscle rdaxant? 1. Datura stramonium 2. Atropa belladonna 3. Hyoscyamus niger 4. Chondrodendron tomentosum 0 1 0 2 {Chosen option) R 0 3 0 4 TE Pharmacology and Allied Subjects - Question No.1 (Question ld - 22795) Marks: 4.00 EN Fight or flight responses are mediated by 1. Parasympathetic division of Autonomous nervous system C 2. Sympathetic di"·ision of Autonomous nervous system 3. Serotonergic nervous system 4. Histaminergic nervous system N IO 0 1 {Chosen option) 0 2 SS 0 3 0 4 Question No.2 (Question ld - 22797) Marks: 4.00 U Which on.: of the following is an autosomal dominant syndrome in its inheritance? C 1. Gilbert's syndrome IS 2. Crigler-Naijar syndrome Type-! D 3. Dubin-Johnson syndrome 4. Rotor syndrome T 0 1 PA 0 2 {Chosen option) 0 3 0 4 G Marks: Question No.3 (Question ld 22804) 4.00 One of the following match is con·ect choose it : 1. M 1 Acetylcholine receptors confined to brain M 2 Acetylcholine receptors neural M 3 Acetylcholine receptors are cardiac M 4 Acetylcholine receptors glandular 2. M 1 Acetylcholine receptors neural M 2 Acetylcholine receptors confined to brain M 3 Acetylcholine receptors are cardiac M 4 Acetylcholine receptors glandular 3. M 1 Acetylcholine receptors neural M 2 Acetylcholine receptors cardiac M 3 Acetylcholine receptors are confined to glandular M4 Acetylcholine receptors confined to brain R 4. M 1 Acetylcholine receptors glandular M 2 Acetylcholine receptors neural M 3 Acetylcholine receptors are confined to brain M4 Acetylcholine receptors cardiac TE 0 1 0 2 0 3 {Chosen option) EN 0 4 Question No.4 (Question ld - 22788) Marks: 4.00 C _ _ is a protein marker \vhich can be detected within three hours of acute ischemic kidney injmy from patient's urine. N 1. N-acetyl- P-D-glncose aminidase IO 2. Glutathione-S-transferase 3. Neutrophil gelatinase associated lipocalin SS 4. ')'-glutamyl tm nspeptidase 0 1 U 0 2 0 3 C 0 4 IS Question No.5 (Question ld - 22798) Marks: 4.00 D ·which of the following genes responsible for graft rejection in humans? 1. Highly polymorphic HLA genes T 2. APP genes PA 3. h1vl:SH2 gene 4. FMRI gene G 0 1 0 2 0 3 0 4 Question No.& (Question ld - 22796) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Match List I with List II LIST I LIST II A. Vibrations in skeletal muscles oflarynx I. IF acia! contractions B. Involuntary contraction of skeletal muscles that is regulated by the brai.tl II. !Regulate voice C. Contraction of skeletal muscles in the legs III. Shivering D. Pull of skeletal muscles on attachments to skin of face IV !Assists return of blood to the heart V. ~auses facial expressions Choose the correct answer from the options given below: 1. (A)-{II); (B)-(ill): (C)- (IV): (D)-(I) R 2. (A)-{III): (B)-(IV): (C)-(I); (D)-(V) TE 3. (A)-{II); (B)-(III): (C)-(IV): (D)-(V) 4. (A)- (III); (B)-(IV); (C)-(V); (D)-(I) EN 0 1 {Chosen option) 0 2 0 3 0 4 C Marks: Question No.7 (Question ld - 22793) 4.00 N IO Most common type of megaloblastic anemia caused by malabsorption of vitamin B 12 and characterized by decreased production of hydrochloric acid in the stomach and a deficiency of intrinsic factor is SS 1. Iron deficiency anemia 2. Sideroblastic anemia U 3. Pemicious anemia C 4. Aplastic anemia IS 0 1 0 2 0 3 {Chosen option) D 0 4 Question No.8 (Question ld - 22799) Marks: 4.00 T PA ·w hich of the following is not an ACE inhibitor? 1. Captopril G 2. Taranclopril 3. Verapamil 4. Lisi.nopril 0 1 0 2 {Chosen option) 0 3 0 4 Question No.9 (Question ld - 22809) Marks: 4.00 6/1/23, 8:00 PM View Question Paper \Vhich of the following combination is con-ect? 1. Nucleoside reverse transcriptase inhibitors (NRTis)- Ritonavir 2. Protease inhibitors - Indinavir 3. lntegrase inhibitors - Saquinavir 4. Non-nucleoside reverse transcriptase inhibitors (NNRTis) -Tenofovir 0 1 0 2 {Chosen option} R 0 3 0 4 TE Question No.1 0 (Question ld - 22805) Marks: 4.00 EN Choose the most appropriate answer : A. Enterobius vermicularis-pin worm B. Strongyloids stercoralis-Thread worm C. Wuchereria bancrofti-Filarial worm D. Dracunculus rnedinensis-Guinea worm C 1. Only B and C are corTect 2. Only A and B are con-ect N IO 3. A, B. C and D are con·ect 4. Only B, C and Dare conect SS 0 1 0 2 0 3 U 0 4 C Question No.11 (Question ld - 22789) Marks: 4.00 IS _ _ actiYates G-protein gated potassimn channel resulting in membrane hyperpolarization. 1. a.1 adrenergic receptor D 2. ~ adrenergic receptor T 3. P1 adrenergic receptor PA 4. p2 adrenergic receptor 0 1 0 2 G 0 3 0 4 {Chosen option} Question No.12 (Question ld - 22811) Marks: 4.00 6/1/23, 8:00 PM View Question Paper \Vhich among the following statement is con·ect with respect to their mechanism of antidiabetic action? 1. Dapagliflozi.n/Canagliflozin-Sodimn glucose cotranspoti-2 inhibitors 2. Glipizide/Giiclazide-Dipeptidyl peptidase-4 inhibitors 3. Linaglitin/Alogliptin-AMPK activators 4. AcarboseNoglibose-K-ATP channel blockers 0 1 0 2 R 0 3 0 4 (Chosen option) TE Question No.13 (Question ld - 22792) Marks: 4.00 EN Prominent biochemical features of Gran 's disease are 1. Decreased ionized calcimn in body fluids 2. Decreased T 4 and T3 in circulation C 3. Increased ionized calcimn in body fluids 4. Increased T4 and T3 in circulation N IO 0 1 0 2 0 3 SS 0 4 (Chosen option) Marks: Question No.14 (Question ld - 22802) 4.00 U Laborat01y findings of which one of the following disease include markedly elevated serum amylase levels C during the fu·st 24 hours followed by rising senun lipase levels \Vithin 72-96 hours? IS 1. Acute pancreatitis 2. Cinhosis of liver D 3. Jaundice T 4. Cystic fibrosis of lungs PA 0 1 0 2 0 3 0 4 G Question No.15 (Question ld - 22790) Marks: 4.00 Exeuatide is a 1. Glucagon like peptide 1 (GLP 1) receptor agonist 2. Diphenyl Peptidase-4 (DPP4) inhibitors 3. Facilitator of glucose transport across the cell 4. Inhibitor of glucose absorption in the GIT 0 1 (Chosen option) 6/1123, 8:00PM View Question Paper 0 2 0 3 I 0 4 I Question No.16 (Question ld - 2281 0) Marks: 4.00 Which of the following is a third generation cephalosporin? 1. Cefazoline 2. Cefuroxime R 3. Cefotaxime 4. Cefepime TE 0 1 0 2 0 3 (Chosen option) EN 0 4 Question No.17 (Question ld ·22814) Marks: 4.00 C D eficiency of _ _ enzyme is found in Hers' disease. 1. muscle glycogen phospho1ylase N IO 2. Ii...-er glycogen phosph01ylase 3. phosphofi11ctokinase SS 4. glucose-6-phosphatase 0 1 0 2 U 0 3 0 4 C Marks: IS Question No.18 (Question ld - 22807) 4.00 D One of the following is correct match or mechanisms. Select it. 1. Methotrexate-Inhibition of microtubules,Vinca alkaloids -Inhibition of Purine.!>ynthesis, Bleomycin- T Inhibition of RNA, 5-Fluoro Uracil-DNA damage PA 2. Methotrexate-Inhibition of Purine synthesis,Vinca alkaloids -Inhibition of Micro tubules, Bleomycin- DNA damage, 5-Piuoro Uracil-inhibition of 2-deo:ll:ythymidylate 3. Methotrexate-D)\)A damage, Vinca alkaloids-Inhibition of micro tubules, Bleomycin-Inhibition of 2- G deoxythymidylate. 5-Fluoro Urac il-RNA damage 4. Methotrexate-DNA damage, Vinca alkaloids-RNA damage, Bleomycin-Inhibition ofPurine synthesis, 5- Fluoro Uracil-Inhibition of 2-deoxythymidylate 0 1 0 2 0 3 (Chosen option) 0 4 Question No.19 (Question ld - 22800) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Para aminohippuric acid (PAH) clearance test is employed t o measure 1. Renal blood flow 2. Liver blood flow 3. Cerebral blood flow 4. Venous blood flo·w 0 1 {Chosen option) R 0 2 0 3 TE 0 4 Question No.20 (Question ld - 22787) Marks: 4.00 EN The !3- adrenergic antagonist propranol ol (20-120 mglkg) is prescribed to around 50% of maniac patients receiYing Lithium is to mitigate the side effect 1. Anxiety C 2. Tremor 3. Hypertension N IO 4. Bradycardia 0 1 0 2 SS 0 3 0 4 U Question No.21 (Question ld - 22794) Marks: 4.00 C Which class of antibody opsonizes antigens for phagocytosis through hvo different pathways? IS 1. Inununoglobulin G (IgG) 2. Immunoglobulin M (IgM) D 3. Immunoglobulin A (IgA) T 4. Inununoglobuli.n E (IgE) PA 0 1 0 2 0 3 0 4 G Question No.22 (Question ld - 22791) Marks: 4.00 Anti-rheumatoid drug which is contm indicated in p atients with renal and hepa6c impainnent 1. Sulfasalazine 2. Methotrexate 3. Cotticosteroids 4. Azathoprine 0 1 0 2 6/1/23, 8:00 PM View Question Paper 0 3 {Chosen option} 0 4 Marks: Question No.23 (Question ld - 22812) 4.00 Which among the following is an amino-alcohol analogue that has weak visceral anticholinergic activ ity but is a strong nicotinolytic drug? l. Biperiden 2. Orphenadrine R 3. Poldine TE 4. Propantheline 0 1 0 2 EN 0 3 0 4 {Chosen option} Marks: C Question No.24 (Question ld - 22803) 4.00 N \V'hich one of the follo\ving interferes with the release of cholinergic neurotransmitter. acetylcholine by the neurons of autonomic nervous system'? IO l. Reserpine 2. Guanethidine SS 3. Hemicholinium 4. Botulinum toxin U 0 1 0 C 2 0 3 {Chosen option} IS 0 4 Marks: Question No.25 (Question ld - 22801) D 4.00 Which one of the following types of hepatitis can lead to fulminant hepatitis causing massive hepatic cell T death more fi·equently among infected pregnant women. showing third trimester mottality as high as 30%? PA 1. Hepatitis A 2. Hepatitis B G 3. Hepatitis C 4. Hepatitis E 0 1 0 2 0 3 0 4 Question No.26 (Question ld - 22806) Marks: 4.00 6/1/23, 8:00 PM View Question Paper Phocomelia is caused by 1. Glibenclamide 2. Indapamide 3. X ipamide 4. Thalidomide 0 1 0 2 R 0 3 0 4 {Chosen option) TE Marks: Question No.27 (Question ld 22808) 4.00 EN Valproate and Carbamazepin e can be used as first line drugs for the management of following type of seizure. 1. Both partial seizme and Tonic-clonic seizure C 2. Both Tonic-clonic seizure and Status epilepticus 3. Only Febrile seizmes 4. Both Febrile seizmes and Status epilepticus N IO 0 1 0 2 {Chosen option) 0 3 SS 0 4 Question No.28 (Question ld - 22813) Marks: 4.00 U Which phase of cell cycle is the shortest phase in tenus of time? C IS 2. S D 3.M T 0 1 PA 0 2 0 3 0 4 {Chosen option) G other Subjects Marks: Question No.1 (Question ld 22819) 4.00 Identify the schedule for which the following cautionaty labelling is mandatory as per Drugs and Cosmetics Act. 1. Use within one month of opening 2. Name and concentration of preservative DROPPED 3. Not for injection 4. If irritation persists or increases, discontinue use and consult physician. Keep container tightly closed. 6/1/23, 8:00 PM View Question Paper 0 1 0 2 0 3 0 4 {Chosen option) Question No.2 (Question ld - 22823) Marks: 4.00 The more appropriate purpose of spiral scrapper in Swenson-Walker ctystalliser is 1. agitation of sample (solution) 2. conveying the ctystals R 3. preYent an accmnulation of ctystals on the cooling sur face TE 4. provides desired temperature to the sample (solution) 0 1 0 2 EN 0 3 0 4 C Question No.3 (Question ld - 22821) Marks: 4.00 If u is velocity of fluid, P is density of fluid, L is length of the pipe, D is diameter of the pipe, f is friction factor and b.P 1 is pressure drop, then the equation N /1~ = ( 2fu 2Lp) -;- D represents. IO 1. Hagen Poiseuille equation SS 2. Bemoulli equation 3. F annings equation 4. Reynolds equation U 0 1 C 0 2 {Chosen option) 0 3 IS 0 4 D Question No.4 (Question ld - 22824) Marks: 4.00 Match List I with List II T LIST I LIST II PA A Penicillin I. Single cell protein B. Pruteen II. Ion exchange chromatography for recoYery C. Streptomycin III. !Primary metabolite D. Amino acids IV. !Phenyl acetic acid as precursor G Choose the con·ect artswer from the options given below: 1. (A)-{II); (B)-{I); (C)-(IV): (D)-(III) 2. (A)-{IV); (B)-(I): (C}-(II) ; (D)-(III) 3. (A)-(III): (B)-(II): (C)-(I): (D)-(IV) 4. (A)--{II): (B)-(III): (C)-(IV); (D)-(I) 0 1 0 2 0 3 0 4 6/1/23, 8:00 PM View Question Paper Question No.5 (Question ld 22815) Marks: 4.00 \Vho is the primaty source of infonnation for doctors' prescribing behaviour? 1. Competitor 2. \~Vhole sa ler 3. Fellow doctor 4. Retailer 0 1 R 0 2 0 3 TE 0 4 Question No.6 (Question ld 22820) Marks: 4.00 EN Schedule ' 0 ' governs the standards for 1. Disinfectant fluids C 2. List of equipment to run a phannacy N 3. Life period (expi1y) of dmgs 4. Manufacturing and analytical records of dmgs IO 0 1 {Chosen option) 0 2 SS 0 3 0 4 U Marks: Question No.7 (Question ld 22818) 4.00 C The number of persons elected as the member of the Phannacy C otmcil of India from the teaching profession IS IS: D 2. Si.x 3. Seven T 4. Eight PA 0 1 0 2 {Chosen option) 0 3 G 0 4 Question No.8 (Question ld 22822) Marks: 4.00 The fluid flows through the filter medium by virtue of 1. pressure difference across the filter 2. temperature difference across the filter 3. \'olume difference across the filter 4. p otential difference across the filter 6/1/23, 8:00 PM View Question Paper 0 1 {Chosen option} 0 2 0 3 0 4 Question No.9 (Question ld - 22825) Marks: 4.00 Match the photophannaceutical with the plant species from which they are produced : LIST I LISTTI (Compound) (Plant species) A. Cardinolides I. jRuJa graveolens R B. Rutin II. Catharanthus roseus C. A.jamalicine IlL !Papaver somnifera D. Codeine IV !Digitalis lanata TE Choose the correct answer fi-om the options given below: L (A)-(IV): (B)-(I): (C)- (II): (D)-(III) EN 2. (A)--(I); (B)-(III): (C)-(II): (D)-(IV) 3. (A)--(III); (B)-(I); (C)-(III): (D)-(IV) C 4. (A)--(II): (B)-(IV); (C)- (I): (D)-(III) 0 1 {Chosen option) 0 2 0 3