Glycolysis Regulation, Cori's Cycle, TCA Cycle, Gluconeogenesis and Hemoglobinopathies PDF
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Uploaded by GiftedJudgment2074
Manipal Academy of Higher Education
2024
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This document contains a biochemistry exam with questions related to glycolysis regulation, Cori's cycle, TCA cycle, gluconeogenesis and hemoglobinopathies. The questions are multiple choice, and the exam was taken on December 16, 2024.
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Glycolysis Regulation, Cori's Cycle, TCA Cycle, Gluconeogenesis and Hemoglobinopathies Biochemistry SDL - 16-12-2024 Points: 90% Correct 1. The product of Glycolysis in erythrocyte:- NADPH Lactate Pyruvate CO2 Correct 2. There is no net synthesis of glucose fro...
Glycolysis Regulation, Cori's Cycle, TCA Cycle, Gluconeogenesis and Hemoglobinopathies Biochemistry SDL - 16-12-2024 Points: 90% Correct 1. The product of Glycolysis in erythrocyte:- NADPH Lactate Pyruvate CO2 Correct 2. There is no net synthesis of glucose from fatty acid, because of the irreversible nature of the reaction : Pyruvate to Oxaloacetate Pyruvate to Acetyl COA Phosphoenol pyruvate to Pyruvate Oxaloacetate to Acetyl COA Correct 3. In Cori's Cycle, lactate is converted to glucose in which organ? Muscle Liver Kidney Heart Correct 4. Which of the following statements regarding Cori's cycle is FLASE: It occurs in the Liver Involves conversion of lactate to glucose Requires ATP in the form of energy It is a catabolic pathway Correct 5. What is the primary function of Cori's cycle in human body ? To generate energy from muscle car contraction To regulate blood glucose levels To conserve energy during periods of low glucose availability To detoxify lactate products during exercise Correct 6. All are inhibitors of phosphofructokinase , EXCEPT Fructose-2,6-bisphosphate ATP Cyclic AMP Citrate Correct 7. What is the fate of glucose produced during Gluconeogenesis: It is stored as glycogen It is released into bloodstream It is used for energy production It is converted to fat Correct 8. Gluconeogenesis is inhibited by: Glucagon Growth hormone Insulin Glucocorticoides Correct 9. All the following are substrate for Gluconeogenesis, EXCEPT Palmitic acid Lactic acid Alanine Glycerol Correct 10. Which of the following regarding Gluconeogenesis is CORRECT: It is an exergonic process It is important in maintaining blood glucose in 2 day fast It occurs in cytosol of the muscle cells It uses carbon skeletons provided by fatty acid degradation Correct 11. Which of the following enzymes is NOT a part of TCA Cycle : Citrate synthase Aconitase Phosphofructokinase Isocitrate dehydrogenase Correct 12. Which compound is NOT a direct product of TCA Cycle: ATP NADH FADH2 Glucose Incorrect 13. Which of the following is an allosteric activator of ISOCITRATE DEHYDROGENASE: ATP NADH Ca+2 ADP Correct 14. Which of the following statements is true about Glycolysis : Total 3 ATPs are used in the pathway Occures in mitochondria End with complete breakdown of glucose Conversion of glucose to 3C units Correct 15. Common enzyme for Gluconeogenesis and Glycolysis is: Glycogen synthase Pyruvate kinase Glyceraldehyde 3 PO4 dehydrogenase Pyruvate carboxylase Correct 16. Lactate is a product of Glycolysis in RBCs because ? RBCs can convert lactate to glucose Formation of lactate produces more energy NAD+ is regenrated in the cytoplasm One of the end products of Glycolysis Correct 17. Which of the following cannot be converted back to glucose? Acetyl COA Lactate Alanine Propionyl - COA Incorrect 18. Which of the following is NOT a substrate for Gluconeogenesis : Lactate Glycerol Propionyl - CoA Pyruvate Correct 19. In HbA, the 6th amino acid is glutamic acid and in HbS, this is replaced by valine. The mobility of HbA and HbS during electrophoresis will be : Both have same mobility HbS moves faster than HbA to anode HbS moves faster than HbA to cathode HbS moves slower than HbA to anode Correct 20. B- thalassemia can result from , EXCEPT Terminator codon mutation Abnormal splicing of mRNA Defect in Post translational processing Mutation in suppressor genes Keep the information with you by saving your response. Save my response This content is created by the owner of the form. The data you submit will be sent to the form owner. Microsoft is not responsible for the privacy or security practices of its customers, including those of this form owner. Never give out your password. Microsoft Forms | AI-Powered surveys, quizzes and polls Create my own form Privacy and cookies | Terms of use