Genes 3: Key Examples of Inherited Conditions - 2.3 PDF
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Uploaded by InnocuousSilver3002
University of Plymouth
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Summary
This document provides an overview of various inherited conditions, including genomics, human genome, genome sequencing, monogenic disorders, cystic fibrosis, sickle cell disease, Duchenne muscular dystrophy, polygenic and multifactorial diseases, pharmacogenomics, and testing for genetic diseases. It discusses different types of inherited conditions and their causes.
Full Transcript
**[Genes 3: key examples of inherited conditions - 2.3]** **Genomics** - - - **Human genome** - - **Genome sequencing** Genome is 0.1% different from another person but 3 million differences **[Monogenic disorders ]** - - **Cystic fibrosis** - - - - - - -...
**[Genes 3: key examples of inherited conditions - 2.3]** **Genomics** - - - **Human genome** - - **Genome sequencing** Genome is 0.1% different from another person but 3 million differences **[Monogenic disorders ]** - - **Cystic fibrosis** - - - - - - - Treatment - - - - - - - **Sickle cell disease** - - - Causes - - **Duchenne muscular dystrophy** - - - - Causes - - Treatment - **[Polygenic and multifactorial diseases]** - - Eg: - - - - Heredity = proportion of variability due to genetic rather than lifestyle High heredity = high genetic component - - - **Pharmacogenomics** How genetic differences in patients determines how their bodies process drugs Eg: - - - **Testing for genetics of disease** Eg: - - - - - - Mitochondrial disease - -
