الاختبار النهائي: توليف الاسبرين PDF

**1. What are the primary uses of salicylic acid in topical treatments?**\ a. As a thickening agent\ b. Treatment of corns and athlete\'s feet\ c. To enhance flavor in foods\ d. As a coloring agent **2. Which property of salicylic acid makes it suitable as a preservative?**\ a. Its ability to chang...

**1. What are the primary uses of salicylic acid in topical treatments?**\ a. As a thickening agent\ b. Treatment of corns and athlete\'s feet\ c. To enhance flavor in foods\ d. As a coloring agent **2. Which property of salicylic acid makes it suitable as a preservative?**\ a. Its ability to change color\ b. Its strong antiseptic and germicidal properties\ c. Its sweet taste\ d. Its high melting point **3. What is a common internal use of salicylic acid derivatives?**\ a. As a laxative\ b. As an antipyretic and analgesic\ c. As a sleep aid\ d. As an antibiotic **4. Why is salicylic acid not typically used internally in its pure form?**\ a. It is too expensive\ b. It lacks any medicinal properties\ c. It can be irritating to the stomach\ d. It has no taste **5. Which of the following is NOT a use of salicylic acid?**\ a. Preserving pharmaceuticals\ b. Flavoring foods\ c. Treating warts\ d. Enhancing texture in cosmetics **6. What is a significant advantage of using derivatives in pharmaceuticals?**\ a. To increase production costs\ b. To increase the effects and decrease side effects\ c. To prolong shelf life\ d. To enhance color and flavor **7. In the synthesis of ASA, what is the role of H2SO4H2​SO4​?**\ a. It acts as a solvent.\ b. It is used as a reducing agent.\ c. It acts as a catalyst in the reaction.\ d. It is the main reactant. **8. Which compound is known as aspirin?**\ a. Salicylic acid\ b. Sulfuric acid\ c. Acetyl salicylic acid\ d. Acetic acid **9. What role does acetic anhydride play in the synthesis of acetyl salicylic acid (ASA) from salicylic acid (SA)?**\ a. It acts as a catalyst.\ b. It provides the acetyl group needed for the reaction.\ c. It neutralizes the acidity of SA.\ d. It is used to dissolve SA. **10. Why is Acetylsalicylic Acid (ASA) less irritating to the stomach compared to Salicylic Acid (SA)?**\ a. ASA is more soluble in water\ b. ASA has a different melting point\ c. ASA is less acidic due to acetylation\ d. ASA is stabilized by intramolecular hydrogen bonding **11.Which statement is true about the melting points of SA and ASA?**\ a. SA and ASA have the same melting point\ b. SA has a higher melting point than ASA\ c. ASA has a higher melting point than SA\ d. Melting point is not applicable to either **12. During recrystallization, what is the desired characteristic of the solvent used?**\ a. High boiling point.\ b. Soluble at room temperature.\ c. The solid should be soluble at high temperatures and insoluble at low temperatures.\ d. High viscosity. **13.Which characteristic is essential for a solvent to be considered chemically inert?**\ a. It reacts readily with the solute\ b. It is non-reactive with the solute\ c. It dissolves all impurities\ d. It has a high boiling point **14.** **What is the chemical name for aspirin?** A\) Benzoic acid B\) Ethanolamine C\) Salicylic acid D\) Acetylsalicylic acid **15. What is the molecular formula of aspirin?** A) C9H8O4 B) C9H10O3 C) C7H6O3 D) C8H10O4 **16. In which solvent is aspirin most soluble?** A) Water B) Chloroform C) Hexane D) none of them **17. What happens to aspirin when it comes in contact with moisture?** A) It forms a new compound. B) It decomposes by hydrolysis. C) It changes color. D) It becomes more potent. **18. Why is the melting point of aspirin not a reliable indicator of its purity?** A) It decomposes upon heating. B) It is highly reactive. C) It melts at a very low temperature. D) It absorbs moisture from the air. **19. Which method of synthesizing aspirin is preferred due to the safety and simplicity of the reagents used?** Choices A) Using pyridine B) Using acetic anhydride C) Using acetyl chloride D) Using acetic acid **20. What is the role of pyridine in the second method of aspirin synthesis?** A) Neutralize HCl produced in the reaction B) Act as an acetylating agent C) Increase the yield of aspirin D) Act as a phenolic group donor **21. What does a negative result in the ferric chloride test indicate about aspirin?** A) Aspirin is more stable than salicylic acid B) Aspirin does not contain a phenolic group C) Aspirin contains a phenolic group D) Aspirin is a weaker acid than salicylic acid **22. Compared to acetic anhydride, what is a major disadvantage of using acetyl chloride in the synthesis of aspirin?** A) It is more expensive B) It reacts less vigorously C) It forms non-corrosive gases D) It produces corrosive HCl gas **23. What is the primary reason that acetyl chloride is avoided in aspirin synthesis despite being more reactive?** A) The resulting product is less stable B) It produces a solid byproduct that complicates purification C) It releases corrosive gases harmful to health D) It is too expensive compared to acetic anhydride **24. Which compound gives a positive result in the ferric chloride test due to the presence of a phenolic group?** A) Salicylic acid B) Acetic anhydride C) Acetyl chloride D) Aspirin **25. What is the order of effectiveness for the acetylation agents mentioned in the synthesis of aspirin?** A) Acetic anhydride \> acetic acid \> acetyl chloride B) Acetyl chloride \> acetic anhydride \> acetic acid C) Acetic acid \> acetyl chloride \> acetic anhydride D) Acetyl chloride \> acetic acid \> acetic anhydride **26. Which compounds are produced when aspirin degrades through hydrolysis?**\ a. Ethanol and acetic acid\ b. Salicylic acid and acetic acid\ c. Acetic anhydride and water\ d. Phenol and carbonic acid **27. What is the role of concentrated H₂SO₄ in the synthesis procedure?**\ a. Solvent\ b. Catalyst\ c. Reactant\ d. Neutralizing agent **28.What happens when water is added after cooling in the synthesis procedure?**\ a. It crystallizes the product\ b. It destroys excess acetic anhydride\ c. It purifies the aspirin\ d. It speeds up the reaction **29. What physical appearance does pure aspirin have?**\ a. Yellow crystals\ b. White powder or colorless crystals\ c. Pink crystalline powder\ d. Brown crystals **30. Which compounds are produced when aspirin degrades through hydrolysis?**\ a. Ethanol and acetic acid\ b. Salicylic acid and acetic acid\ c. Acetic anhydride and water\ d. Phenol and carbonic acid