Homeostatic Regulation of the Kidney PDF
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Uploaded by MesmerizedMoldavite7389
ANTH/LING
2021
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Summary
This document discusses the homeostatic regulation of the kidney, focusing on the interplay of nervous and hormonal inputs. It explains how these inputs contribute to maintaining blood pressure and volume homeostasis. The document also examines the role of Antidiuretic Hormone (ADH) and the renin-angiotensin-aldosterone system (RAAS) in kidney function.
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Homeostatic Regulation of the Kidney (신장의 항상성 조절기능) • A combination of nervous and hormonal inputs regulates the osmoregulatory function of the kidney (신경 및 호르몬 입력의 조합은 신장의 산도 조절 기능을 조절함) • These inputs contribute to homeostasis for blood pressure and volume (이러...
Homeostatic Regulation of the Kidney (신장의 항상성 조절기능) • A combination of nervous and hormonal inputs regulates the osmoregulatory function of the kidney (신경 및 호르몬 입력의 조합은 신장의 산도 조절 기능을 조절함) • These inputs contribute to homeostasis for blood pressure and volume (이러한 입력은 혈압과 체내 수분양 항상성에 기여함) Copyright © 2021 Pearson Education Ltd. All Rights Reserved Antidiuretic Hormone (항이뇨호르몬) • Antidiuretic hormone (ADH, 항이뇨호르몬) makes the collecting duct epithelium temporarily more permeable to water (항이뇨호르몬은 집합관 상피의 수분 투과성을 일시적으로 높여준다 – 소변양 감소, 체액 보존) • An increase in blood osmolarity above a set point triggers the release of ADH, which helps to conserve water (혈중 삼투압이 설정점 이상으로 증가하면 수분 보존에 도움이 되는 ADH가 방출됨) • Decreased osmolarity causes a drop in ADH secretion and a corresponding decrease in permeability of collecting ducts (삼투압이 감소하면 ADH 분비량이 감소하고 이에 따라 집합관의 투과성이 감소함) Copyright © 2021 Pearson Education Ltd. All Rights Reserved Animation: Effect of ADH Copyright © 2021 Pearson Education Ltd. All Rights Reserved 시상하부의 삼투수용기가 뇌하수체의 ADH 분비 촉발 정상 혈액 삼투농도 Figure 32.24 Regulation of Fluid Retention in the Kidney by Antidiuretic Hormone (ADH) (항이뇨호르몬에 의한 신장의 수분조절 Copyright © 2021 Pearson Education Ltd. All Rights Reserved Coordination of Kidney Regulation (신장조절의 조율) • The renin-angiotensin-aldosterone system (RAAS) also regulates kidney function (레닌-안지오텐신-알도스테론 시스템(RAAS)은 신장 기능도 조절한다) • A peptide called angiotensin II (안지오텐신 II) is a product of the RAAS • Angiotensin II raises blood pressure and decreases blood flow to capillaries in the kidney (안지오텐신 II는 혈압을 높이고 신장의 모세혈관으로 가는 혈류를 감소시킴) • Drugs that block angiotensin II production are used to treat hypertension (chronic high blood pressure) (안지오텐신 II 생성을 차단하는 약물은 고혈압을 치료하는 데 사용됨) Copyright © 2021 Pearson Education Ltd. All Rights Reserved