Anxiolytic and Hypnotic Drugs Part 5.docx

1\. \*\*Which antihistamine is frequently used for treating insomnia?\*\* \- A) Hydroxyzine \- B) Cetirizine \- C) Loratadine \- D) Fexofenadine \*\*Answer\*\*: A) Hydroxyzine 2\. \*\*What is a common adverse effect associated with using first-generation antihistamines like diphenhydramine for...

1\. \*\*Which antihistamine is frequently used for treating insomnia?\*\* \- A) Hydroxyzine \- B) Cetirizine \- C) Loratadine \- D) Fexofenadine \*\*Answer\*\*: A) Hydroxyzine 2\. \*\*What is a common adverse effect associated with using first-generation antihistamines like diphenhydramine for insomnia?\*\* \- A) Hypertension \- B) Daytime sedation \- C) Insomnia rebound \- D) Seizures \*\*Answer\*\*: B) Daytime sedation 3\. \*\*Which population is generally advised to avoid first-generation antihistamines like diphenhydramine?\*\* \- A) Pregnant women \- B) Children \- C) Elderly patients \- D) Patients with anxiety \*\*Answer\*\*: C) Elderly patients 4\. \*\*What is the primary mechanism of action of buspirone?\*\* \- A) GABA agonist \- B) Full agonist at 5-HT1a receptors \- C) Antagonist at serotonin receptors \- D) Blocker of norepinephrine reuptake \*\*Answer\*\*: B) Full agonist at 5-HT1a receptors 5\. \*\*How long does it typically take for buspirone to achieve full therapeutic effects?\*\* \- A) 1-2 days \- B) 3-4 weeks \- C) 1 week \- D) 24 hours \*\*Answer\*\*: B) 3-4 weeks 6\. \*\*Why is buspirone considered advantageous over benzodiazepines for chronic anxiety treatment?\*\* \- A) It has a faster onset of action \- B) It carries no risk of dependence or withdrawal \- C) It is stronger in sedation \- D) It works immediately to relieve anxiety \*\*Answer\*\*: B) It carries no risk of dependence or withdrawal \#\#\# Slide 45 - Melatonin and Related Drugs 7\. \*\*What is the primary function of melatonin in sleep regulation?\*\* \- A) It decreases sleep latency and enhances REM sleep \- B) It induces wakefulness \- C) It regulates the circadian rhythm and induces sleep \- D) It increases daytime alertness \*\*Answer\*\*: C) It regulates the circadian rhythm and induces sleep 8\. \*\*Which melatonin receptor agonist is used specifically for sleep onset insomnia?\*\* \- A) Zolpidem \- B) Ramelteon \- C) Zaleplon \- D) Eszopiclone \*\*Answer\*\*: B) Ramelteon 9\. \*\*What is a contraindication for using ramelteon?\*\* \- A) Pregnancy \- B) Severe renal impairment \- C) Concurrent use with fluvoxamine \- D) Alcohol use \*\*Answer\*\*: C) Concurrent use with fluvoxamine 10\. \*\*What is the mechanism of action of suvorexant, an orexin antagonist?\*\* \- A) It blocks GABA receptors \- B) It inhibits the action of orexins A and B \- C) It enhances melatonin production \- D) It increases serotonin levels \*\*Answer\*\*: B) It inhibits the action of orexins A and B 11\. \*\*What is a common adverse effect of orexin antagonists like suvorexant?\*\* \- A) Sleep paralysis \- B) Weight loss \- C) Insomnia \- D) Increased daytime alertness \*\*Answer\*\*: A) Sleep paralysis 12\. \*\*Which sleep condition is suvorexant primarily used to treat?\*\* \- A) Anxiety \- B) Narcolepsy \- C) Sleep onset and maintenance insomnia \- D) Seizures \*\*Answer\*\*: C) Sleep onset and maintenance insomnia