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# Effect of Various Factors on DLCO **Fick's Law of Diffusion:** $V_m = \frac{Surface \ area \times Solubility \times \Delta P}{Sq. \ root \ molecular \ weight \times thickness}$ **Factors that decrease DLCO:** * Anemia * Carboxyhemoglobin * Pulmonary embolism * Diffuse pulmonary fibrosis * Pulm...

# Effect of Various Factors on DLCO **Fick's Law of Diffusion:** $V_m = \frac{Surface \ area \times Solubility \times \Delta P}{Sq. \ root \ molecular \ weight \times thickness}$ **Factors that decrease DLCO:** * Anemia * Carboxyhemoglobin * Pulmonary embolism * Diffuse pulmonary fibrosis * Pulmonary emphysema **Factors that increase DLCO:** * Polycythemia * Exercise * Congestive heart failure