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### Non-Bronchodilators - what we prevent - **Leukotriene receptor antagonist** - black-leukotriene (promotes inflammation) - slow onset - dilation and permeability - adverse effect - liver dysfunction - bronchoconstriction worsen at night sometimes - montelukast ###...

### Non-Bronchodilators - what we prevent - **Leukotriene receptor antagonist** - black-leukotriene (promotes inflammation) - slow onset - dilation and permeability - adverse effect - liver dysfunction - bronchoconstriction worsen at night sometimes - montelukast ### Corticosteroids (aka Glucocorticoids) - Dual effect- role in acute exacerbation - Alone won't enhance activity of beta-energetics - need LABA - Salbutamol + corticosteroid - adjuvant - also: px release of harmful substances - histamine ### Primary tx - IV adm: only x acute exacerbation / severe asthma - immunosuppressive - 1 glucose - Inskx hypokalemia/w/concurrent we =* depletion - Budesonide (Pulmicort Turbhaler) - Fluticasone propionate (Flovent Diskus)