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## **Mometrix** ### **Von Willebrand Disease** A glycoprotein that is synthesized, stored and secreted by vascular endothelial cells. This protein interacts with thrombocytes to create a clot and prevent hemorrhage; however, with von Willebrand disease, this clotting mechanism is impaired. There a...

## **Mometrix** ### **Von Willebrand Disease** A glycoprotein that is synthesized, stored and secreted by vascular endothelial cells. This protein interacts with thrombocytes to create a clot and prevent hemorrhage; however, with von Willebrand disease, this clotting mechanism is impaired. There are 3 types: - **Type I:** Low levels of vWF and sometimes factor VIII. (Dominant inheritance) - **Type II:** Abnormal of and sometimes factors or decrease clotting. (Dominant inheritance) - **Type III:** Absence of vWF and