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## FIGURE 6.2 Gastrointestinal hormones, paracrines, and neurocrines. ### a. Actions of gastrin 1. increases H⁺ secretion by the gastric parietal cells. 2. stimulates growth of gastric mucosa by stimulating the synthesis of RNA and new protein. Patients with gastrin-secreting tumors have hypertroph...

## FIGURE 6.2 Gastrointestinal hormones, paracrines, and neurocrines. ### a. Actions of gastrin 1. increases H⁺ secretion by the gastric parietal cells. 2. stimulates growth of gastric mucosa by stimulating the synthesis of RNA and new protein. Patients with gastrin-secreting tumors have hypertrophy and hyperplasia of the gastric mucosa. ### b. Stimuli for secretion of gastrin * Gastrin is secreted from the G cells of the gastric antrum in response to a meal. * Gastrin is secreted in response to the following: 1. small peptides and amino acids in the lumen of the stomach. * The most potent stimuli for gastrin secretion are phenylalanine and tryptophan.