Write a short note on (any four): protein structure, super secondary structure of protein, the mechanism of protein folding and its significance, strategies for large-scale sequenc... Write a short note on (any four): protein structure, super secondary structure of protein, the mechanism of protein folding and its significance, strategies for large-scale sequencing projects, bioinformatics tools for the analysis of sequence data. Which of the following amino acids are known as a helix breaker?
Understand the Problem
The question is asking for short notes on specific topics related to biotechnology, protein structure, and bioinformatics. It also includes a multiple-choice question regarding amino acids and their properties.
Answer
Proline
The final answer is Proline. It is known as a helix breaker due to its unique structure that disrupts the regular helical backbone conformation.
Answer for screen readers
The final answer is Proline. It is known as a helix breaker due to its unique structure that disrupts the regular helical backbone conformation.
More Information
Proline is often found at the ends of helices where its rigid structure introduces bends or kinks, which disrupt regular alpha-helix formation.
Tips
Be careful not to confuse helix-breaking amino acids with those that stabilize helices.
Sources
- Protein structure: Primary, secondary, tertiary & quatrenary (article) - khanacademy.org
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