Which one is more stable in SN2 reaction: benzyl or methyl?
Understand the Problem
The question is asking for a comparison of the stability of benzyl and methyl groups in the context of an SN2 reaction. The SN2 reaction is a type of nucleophilic substitution reaction, and the stability of the leaving group can influence the reaction pathway. This requires knowledge of organic chemistry concepts.
Answer
Methyl is more stable in SN2 reaction than benzyl.
Methyl is more stable in an SN2 reaction than benzyl.
Answer for screen readers
Methyl is more stable in an SN2 reaction than benzyl.
More Information
In SN2 reactions, the transition state stability depends largely on sterics, where less steric hindrance allows for a faster reaction. Methyl, having less steric bulk than benzyl, provides a cleaner pathway for nucleophilic attack.
Tips
A common mistake is confusing SN1 and SN2 preferences because benzyl is more reactive towards SN1 due to carbocation stability, but SN2 is about steric hindrance where methyl is superior.
Sources
- The SN2 Reaction Mechanism - Master Organic Chemistry - masterorganicchemistry.com
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