Which of the following statements about the Toxoplasma bradyzoite is true? When bradyzoites are introduced into unsupplemented cat intestinal organoids, the bradyzoites will underg... Which of the following statements about the Toxoplasma bradyzoite is true? When bradyzoites are introduced into unsupplemented cat intestinal organoids, the bradyzoites will undergo robust development into gametes. The cat intestinal organoid is a monolayer of a single cell type which facilitates molecular investigations of Toxoplasma development. Inhibiting delta-6 desaturase in the mouse intestine recapitulates the intestinal environment of the cat gut with respect to linoleic acid concentration. The tachyzoite to bradyzoite transformation occurs when the host enters the acute stage of infection. In a healthy person, the bradyzoites are completely eliminated by the host immune system.
Understand the Problem
The question is asking us to identify which statement about Toxoplasma bradyzoites is true from a list of statements provided. We will evaluate the accuracy of each statement based on knowledge of Toxoplasma lifecycle and host interactions.
Answer
Bradyzoites develop into gametes in unsupplemented cat intestinal organoids.
When bradyzoites are introduced into unsupplemented cat intestinal organoids, the bradyzoites will undergo robust development into gametes.
Answer for screen readers
When bradyzoites are introduced into unsupplemented cat intestinal organoids, the bradyzoites will undergo robust development into gametes.
More Information
In the feline intestine, bradyzoites transform into merozoites and then undergo sexual differentiation. This implies that entering a suitable environment like the cat's intestine is key for this transformation.
Tips
A common mistake is misunderstanding the life cycle of Toxoplasma gondii and the specific stages that occur in the cat's intestine.
Sources
- Exploring Toxoplasma gondii´s Biology within the Intestinal Epithelium - frontiersin.org
- US20210121545A1 - Toxoplasma gondii vaccine - patents.google.com
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