Which of the following is the most appropriate treatment for a 10-year-old boy presenting with jaundice, Kayser-Fleischer rings, elevated bilirubin and liver enzymes, and low cerul... Which of the following is the most appropriate treatment for a 10-year-old boy presenting with jaundice, Kayser-Fleischer rings, elevated bilirubin and liver enzymes, and low ceruloplasmin?
Understand the Problem
The question describes a 10-year-old boy with symptoms and lab results indicative of a specific condition. The task is to identify the most appropriate treatment option from the list provided based on the given information. The key is to recognize the condition based on the symptoms (jaundice, Kayser-Fleischer ring, abdominal distention) and lab results (elevated bilirubin and liver enzymes, low ceruloplasmin) to choose the correct treatment.
Answer
The most appropriate treatment is copper-chelating agents, possibly a liver transplant in advanced stages, as the boy likely has Wilson's disease.
Based on the symptoms (jaundice, Kayser-Fleischer rings, elevated bilirubin and liver enzymes, and low ceruloplasmin), the boy likely has Wilson's disease. The most appropriate treatment would be copper-chelating agents. In advanced stages, a liver transplant might be required.
Answer for screen readers
Based on the symptoms (jaundice, Kayser-Fleischer rings, elevated bilirubin and liver enzymes, and low ceruloplasmin), the boy likely has Wilson's disease. The most appropriate treatment would be copper-chelating agents. In advanced stages, a liver transplant might be required.
More Information
Wilson's disease is a rare autosomal recessive inherited disorder of copper metabolism that is characterized by excessive deposition of copper in the liver.
Tips
It is important to consider Wilson's disease in patients presenting with liver issues, especially when Kayser-Fleischer rings are present along with low ceruloplasmin levels. Copper chelating agents are typically the first line of treatment.
Sources
- Wilson disease: Clinical manifestations, diagnosis, and natural history - uptodate.com
- EASL Clinical Practice Guidelines: Wilson's disease - ScienceDirect - sciencedirect.com
- Wilson Disease: Practice Essentials, Background, Etiology - emedicine.medscape.com
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