Which of the following is the most appropriate action to be done? A. No further testing B. Perform liver ultrasound C. Repeat HCV antibody testing D. Perform serial alanine aminotr... Which of the following is the most appropriate action to be done? A. No further testing B. Perform liver ultrasound C. Repeat HCV antibody testing D. Perform serial alanine aminotransferase monitoring
Understand the Problem
The question presents a clinical scenario involving a 35-year-old nurse who tested positive for hepatitis C antibodies but has a negative HCV RNA test. The task is to determine the most appropriate clinical action based on the provided lab results.
Answer
Perform serial alanine aminotransferase monitoring.
The most appropriate action is to perform serial alanine aminotransferase monitoring.
Answer for screen readers
The most appropriate action is to perform serial alanine aminotransferase monitoring.
More Information
Since the HCV RNA test is negative, hepatic injury concerns can be monitored by observing alanine aminotransferase levels over time, as this will help detect any evolving hepatic issues.
Tips
A common mistake is assuming a negative RNA test requires no further action. However, monitoring liver enzymes like ALT ensures any subclinical infection is observed.
Sources
- HCV Testing and Linkage to Care - hcvguidelines.org
- Clinical Screening and Diagnosis for Hepatitis C - CDC - cdc.gov
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