Which of the following is NOT an example of a natural ligand that binds to GPCRs? A) Neurotransmitters B) Chemoattractants C) Hormones D) Enzymes
Understand the Problem
The question is asking to identify which option is not a natural ligand that binds to G protein-coupled receptors (GPCRs). This involves understanding what natural ligands are in the context of GPCRs and which option among the provided ones does not fit this definition.
Answer
Enzymes
The final answer is D) Enzymes
Answer for screen readers
The final answer is D) Enzymes
More Information
Enzymes are not ligands that bind to G protein-coupled receptors (GPCRs). GPCRs typically bind ligands such as neurotransmitters, chemoattractants, and hormones to mediate cellular responses.
Tips
A common mistake might be assuming that because enzymes are involved in many biological processes, they might also bind to GPCRs directly. However, enzymes often act internally in cells rather than as ligands binding to surface receptors.
Sources
- G protein-coupled receptor - Wikipedia - en.wikipedia.org
- G Protein-Coupled Receptors (GPCRs)-Mediated Calcium Signaling ... - pmc.ncbi.nlm.nih.gov
- G protein-coupled receptors (GPCRs): advances in structures ... - nature.com
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