Which of the following genetic polymorphisms is responsible for Huntington's Disease?
Understand the Problem
The question is asking which genetic polymorphism is responsible for Huntington's Disease, presenting several options related to genetic and neurobiological mechanisms.
Answer
CAG trinucleotide repeats.
The genetic polymorphism responsible for Huntington's Disease is the CAG trinucleotide repeats.
Answer for screen readers
The genetic polymorphism responsible for Huntington's Disease is the CAG trinucleotide repeats.
More Information
Huntington's Disease is caused by an expanded CAG repeat in the HTT gene. This genetic mutation leads to neurodegeneration.
Tips
A common mistake is confusing Huntington's with diseases caused by other types of genetic mutations, such as Alzheimer's.
Sources
- Huntington Disease - GeneReviews® - NCBI Bookshelf - ncbi.nlm.nih.gov
- Huntington's disease: MedlinePlus Genetics - medlineplus.gov
- Huntington's Disease: The Discovery of the Huntingtin Gene - Nature - nature.com
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