Which of the following describes the autocatalytic reaction involving glycogenin? A) Addition of glucose residues to debranch glycogen chains B) Formation of α1→6 bonds using CDP-g... Which of the following describes the autocatalytic reaction involving glycogenin? A) Addition of glucose residues to debranch glycogen chains B) Formation of α1→6 bonds using CDP-glucose C) Formation of a glycosidic bond between UDP-glucose and Tyr194 of glycogenin D) Transfer of glucose from the liver to the muscle
Understand the Problem
The question is asking for the correct description of the autocatalytic reaction involving glycogenin. The options provided refer to various biochemical processes related to glycogen metabolism, and the task is to identify the accurate one.
Answer
Formation of a glycosidic bond between UDP-glucose and Tyr194 of glycogenin.
The final answer is Formation of a glycosidic bond between UDP-glucose and Tyr194 of glycogenin.
Answer for screen readers
The final answer is Formation of a glycosidic bond between UDP-glucose and Tyr194 of glycogenin.
More Information
Glycogenin initiates glycogen synthesis by attaching the first glucose unit to itself, specifically to the Tyr194 residue. This autocatalytic step facilitates further chain elongation.
Tips
A common mistake is confusing the role of glycogenin with that of glycogen synthase, which adds more glucose units to forming glycogen chains.
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