Which of the following correctly describes the activity or regulation of E. coli ribonucleotide reductase?
Understand the Problem
The question is asking which statement accurately describes the activity or regulation of E. coli ribonucleotide reductase among the provided options.
Answer
A: The overall activity of the enzyme is controlled by ATP and dATP.
The final answer is A: The overall activity of the enzyme is controlled by ATP and dATP.
Answer for screen readers
The final answer is A: The overall activity of the enzyme is controlled by ATP and dATP.
More Information
E. coli ribonucleotide reductase's activity is regulated allosterically by ATP and dATP, which are crucial for maintaining the proper balance of deoxyribonucleotides required for DNA synthesis.
Tips
A common mistake is assuming that specificity is controlled by all four dNTPs; however, it is specifically regulated by ATP and dATP.
Sources
- How ATP and dATP Act as Molecular Switches to Regulate - pubs.acs.org
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