Which method is considered the best for estimating bias in an analytical method? A) Blank determinations. B) Variation in sample size. C) Independent analysis using a different met... Which method is considered the best for estimating bias in an analytical method? A) Blank determinations. B) Variation in sample size. C) Independent analysis using a different method. D) Using standard reference materials.
Understand the Problem
The question is asking for the best method to estimate bias in an analytical method. It provides multiple choice options and requires an understanding of analytical techniques to determine which option is the most appropriate for estimating bias.
Answer
Using standard reference materials.
The best method for estimating bias in an analytical method is using standard reference materials.
Answer for screen readers
The best method for estimating bias in an analytical method is using standard reference materials.
More Information
Using standard reference materials allows an analyst to compare the results with a known value, thus directly estimating the bias of the method.
Tips
A common mistake is confusing the measurement of bias with measuring accuracy or precision. Bias specifically refers to the systematic error component.
Sources
- Chapter 5: Errors in Chemical Analyses - web.iyte.edu.tr
- Chapter 6, Selection and Application of an Analytical Method - epa.gov
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