Which first generation antihistamines are likely to cause the most sedation?

Understand the Problem

The question is asking for a specific classification of first generation antihistamines based on their sedative effects. It seeks to identify which among the listed options is most likely to cause sedation.

More Information

First-generation antihistamines can cross the blood-brain barrier, which leads to sedation by affecting the central nervous system.

Tips

Confusing first-generation antihistamines with second-generation ones, which have a lower incidence of sedation.

Sources

• Antihistamines and allergy - PMC - pmc.ncbi.nlm.nih.gov
• First-generation antihistamines - winter warning - tga.gov.au