Which drug acts mainly by preventing the release of norepinephrine at nerve endings? A) Metyrosine B) Guanethidine C) Bretylium D) Reserpine

Understand the Problem

The question is asking to identify a drug that primarily functions by inhibiting the release of norepinephrine at nerve endings. To solve this, we would need to understand the mechanisms of action of the listed drugs.

Answer

Guanethidine

The drug that acts mainly by preventing the release of norepinephrine at nerve endings is Guanethidine.

Answer for screen readers

The drug that acts mainly by preventing the release of norepinephrine at nerve endings is Guanethidine.

More Information

Guanethidine works by inhibiting the release and/or distribution of norepinephrine from sympathetic nerve endings, which makes it effective in reducing blood pressure.

Tips

A common mistake is confusing the mechanisms of guanethidine and reserpine. Reserpine depletes norepinephrine by binding vesicular monoamine transporters.

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