What role does insulin play in the regulation of ACC1?
Understand the Problem
The question is inquiring about the specific role of insulin in the regulation of ACC1 (Acetyl-CoA Carboxylase 1), particularly focusing on how insulin affects its activity, either through phosphorylation/dephosphorylation or other metabolic pathways.
Answer
Insulin stimulates ACC1 transcription, promoting lipogenesis.
Insulin stimulates the transcriptional activity of ACC1, which is involved in promoting lipogenesis.
Answer for screen readers
Insulin stimulates the transcriptional activity of ACC1, which is involved in promoting lipogenesis.
More Information
Insulin regulates ACC1 by up-regulating its promoter activity, leading to an increase in the transcription of genes involved in lipogenesis.
Sources
- Insulin and AC1 Transcription - Endocrinology Journal - jstage.jst.go.jp
- Fatty acid metabolism - ScienceDirect - sciencedirect.com
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