What is the treatment of angina pectoris and how do beta-adrenoceptor blocking drugs work in this context?
Understand the Problem
The question is focused on the treatment of angina pectoris with a particular emphasis on beta-adrenoceptor blocking drugs, their effects, and guidelines for their use. It discusses selectivity, agonistic activity, lipid solubility, and the appropriate heart rate for their effective application.
Answer
Beta blockers reduce heart rate and contractility, decreasing heart's oxygen demand.
Beta-adrenoceptor blocking drugs, or beta blockers, are used to treat angina pectoris by reducing myocardial contractility and heart rate, thus decreasing oxygen demand of the heart. They improve both objective and subjective symptoms in patients with stable angina.
Answer for screen readers
Beta-adrenoceptor blocking drugs, or beta blockers, are used to treat angina pectoris by reducing myocardial contractility and heart rate, thus decreasing oxygen demand of the heart. They improve both objective and subjective symptoms in patients with stable angina.
More Information
Beta blockers mitigate angina symptoms by slowing the heart rate and reducing myocardial contractility. Selective beta-1 blockers target heart-associated receptors more selectively, minimizing side effects in comparison to non-selective blockers.
Tips
Common mistakes include confusing beta blockers with other heart medications or miscalculating safe dosing levels. It's important to monitor heart rate closely.
Sources
- British Heart Foundation - Beta Blockers - bhf.org.uk
- Angina Pectoris Treatment & Management - Medscape Reference - emedicine.medscape.com
- Beta‐blockers for unstable angina - PubMed Central - pmc.ncbi.nlm.nih.gov
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