What is the role of lentivirus retroviruses in gene modification?
Understand the Problem
The question is asking about the role of lentivirus retroviruses in the process of gene modification, specifically regarding their efficiency in gene integration and expression. It presents four options that describe various effects of lentivirus retroviruses on this process.
Answer
Lentivirus retroviruses enable gene modification by integrating genes into host genomes, aiding stable gene therapy.
Lentivirus retroviruses are used in gene modification because they can insert, modify, or delete genes in organisms by integrating DNA into host cell genomes. This makes them useful for stable gene therapy.
Answer for screen readers
Lentivirus retroviruses are used in gene modification because they can insert, modify, or delete genes in organisms by integrating DNA into host cell genomes. This makes them useful for stable gene therapy.
More Information
Lentivirus-based vectors are especially valuable because they can deliver genetic material into both dividing and nondividing cells, a significant advantage over some other viral vectors. This allows for more versatile applications in gene therapy.
Tips
A common mistake is confusing lentiviruses with other retroviruses that might not work as efficiently in nondividing cells. Lentiviruses have this unique capability making them suitable for a broader range of gene therapy applications.
Sources
- Lentiviral and Retroviral Vectors in Gene Therapy - ncbi.nlm.nih.gov
- Clinical use of lentiviral vectors | Leukemia - Nature - nature.com
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