What is the relationship between the POMC pathway and the NPY system?
Understand the Problem
The question is asking about the biological relationship between the POMC (Proopiomelanocortin) pathway and the NPY (Neuropeptide Y) system in the context of food intake regulation. It provides multiple-choice answers that suggest different types of interactions between these two pathways, requiring knowledge of neurobiology to answer correctly.
Answer
NPY increases food intake; POMC decreases it. NPY controls POMC activity.
The POMC pathway and the NPY system have opposing roles in the regulation of energy balance. NPY neurons increase food intake and decrease energy expenditure, while POMC neurons decrease food intake and increase energy expenditure. NPY neurons also control the activity of POMC neurons.
Answer for screen readers
The POMC pathway and the NPY system have opposing roles in the regulation of energy balance. NPY neurons increase food intake and decrease energy expenditure, while POMC neurons decrease food intake and increase energy expenditure. NPY neurons also control the activity of POMC neurons.
More Information
The arcuate nucleus of the hypothalamus houses both NPY and POMC neurons, which play critical roles in hunger and satiety signaling.
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Sources
- Neuropeptide Y and Metabolism Syndrome: An Update on ... - NCBI - ncbi.nlm.nih.gov
- AgRP/NPY and POMC neurons in the arcuate nucleus and their ... - sciencedirect.com
- The web page with info on - Example Source - ncbi.nlm.nih.gov
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