What is the net result of excitatory post-synaptic potentials (EPSPs)?
Understand the Problem
The question is asking about the effect of excitatory post-synaptic potentials (EPSPs) on neuronal membrane potential. EPSPs typically lead to depolarization of the neuron, which means the inside of the neuron becomes less negative compared to the outside, thus making it more likely to fire an action potential.
Answer
Membrane depolarization due to Na+ influx.
The net result of excitatory post-synaptic potentials (EPSPs) is the entry of positive charge carried by Na+ ions leading to membrane depolarization.
Answer for screen readers
The net result of excitatory post-synaptic potentials (EPSPs) is the entry of positive charge carried by Na+ ions leading to membrane depolarization.
More Information
EPSPs contribute to the generation of action potentials in neurons by depolarizing the postsynaptic membrane.
Tips
A common mistake is confusing EPSPs with inhibitory postsynaptic potentials (IPSPs), which hyperpolarize the membrane.
Sources
- Excitatory postsynaptic potential - ScienceDirect - sciencedirect.com
- Excitatory and Inhibitory Postsynaptic Potentials - Neuroscience - ncbi.nlm.nih.gov
- Excitatory postsynaptic potential - Wikipedia - en.wikipedia.org
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